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Protein Overview: FRDA_ECOLI

General Information:
Name(s) found: FRDA_ECOLI [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • Fumarate reductase flavoprotein subunit (EC 1.3.99.1) - Escherichia coli [Swiss-Prot]
    • Organism: Escherichia coli
    Length: 602 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTFQADLAI VGAGGAGLRA AIAAAQANPN AKIALISKVY PMRSHTVAAE GGSAAVAQDH  60
   61 DSFEYHFHDT VAGGDWLCEQ DVVDYFVHHC PTEMTQLELW GCPWSRRPDG SVNVRRFGGM 120
  121 KIERTWFAAD KTGFHMLHTL FQTSLQFPQI QRFDEHFVLD ILVDDGHVRG LVAMNMMEGT 180
  181 LVQIRANAVV MATGGAGRVY RYNTNGGIVT GDGMGMALSH GVPLRDMEFV QYHPTGLPGS 240
  241 GILMTEGCRG EGGILVNKNG YRYLQDYGMG PETPLGEPKN KYMELGPRDK VSQAFWHEWR 300
  301 KGNTISTPRG DVVYLDLRHL GEKKLHERLP FICELAKAYV GVDPVKEPIP VRPTAHYTMG 360
  361 GIETDQNCET RIKGLFAVGE CSSVGLHGAN RLGSNSLAEL VVFGRLAGEQ ATERAATAGN 420
  421 GNEAAIEAQA AGVEQRLKDL VNQDGGENWA KIRDEMGLAM EEGCGIYRTP ELMQKTIDKL 480
  481 AELQERFKRV RITDTSSVFN TDLLYTIELG HGLNVAECMA HSAMARKESR GAHQRLDEGC 540
  541 TERDDVNFLK HTLAFRDADG TTRLEYSDVK ITTLPPAKRV YGGEADAADK AEAANKKEKA 600
  601 NG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..602] PSI-BLAST 135.0 E. coli Quinol fumarate reductase FrdA E49Q mutation

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • succinate dehydrogenase activity
    		•  10.1697547809338 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor
    		•  8.87698547678677 bayes_pls_golite062009
  • succinate dehydrogenase (ubiquinone) activity
    		•  8.87698547678677 bayes_pls_golite062009
  • L-aspartate oxidase activity
    		•  7.97437641217089 bayes_pls_golite062009
  • aspartate oxidase activity
    		•  7.32727957948448 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-CH group of donors
    		•  6.81299528298802 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  5.74880353813045 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
    		•  5.00880700655468 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.62076392207627 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  3.86336671540719 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.57282017498189 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.50603438449246 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.28982462439281 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  2.26549080531565 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  2.16428165652808 bayes_pls_golite062009
  • electron carrier activity
    		•  1.96249176032145 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  1.91979117253135 bayes_pls_golite062009
  • binding
    		•  1.343461862937 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  1.18990628739838 bayes_pls_golite062009
  • antioxidant activity
    		•  1.12347155061135 bayes_pls_golite062009
  • catalytic activity
    		•  1.02941336036162 bayes_pls_golite062009
  • transporter activity
    		•  0.890824576391732 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  0.798505263716232 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.706117386114413 bayes_pls_golite062009
  • ferredoxin reductase activity
    		•  0.61713057030514 bayes_pls_golite062009
  • oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor
    		•  0.61713057030514 bayes_pls_golite062009
  • ferredoxin-NADP+ reductase activity
    		•  0.61713057030514 bayes_pls_golite062009
  • FAD binding
    		•  0.525342258522943 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.491481205015383 bayes_pls_golite062009
  • coenzyme binding
    		•  0.48211536331404 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  0.468246082354334 bayes_pls_golite062009
  • protein binding
    		•  0.404450175883241 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.26114823844682 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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