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Protein Overview: gi|7470855

General Information:
Name(s) found: gi|7470855 [NCBI NR]
Description(s) found:
Found 2 descriptions.
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  • pir||S75130 sensory transduction histidine kinase slr2098 - Synechocystis sp. (strain PCC 6803) [NCBI NR]
    • Organism: Synechocystis sp.
    Length: 1261 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFWQPVSPLN ADQLNYQGSY DPKLVLLSVA IAIFTAYMAF LMASSALSLP GRWSRKIALA  60
   61 LSGTVMGLGI WAMHFIGMLG FELPCPISYD PLITFISVIP AIAASIYALN FLSFQAPTAK 120
  121 NLMVGAIWFG LGIGTMHYSG MAALELHGNI YYELPLFVLS LVIAVMLAFV ALLFRFHSAK 180
  181 IFHTTHGPAL GSSALVMGLS TSGMHYTAMT ATHFICRPWG EFFIQGIDIQ EVAIAVTISI 240
  241 TLLTGGVMLF VLREISIQNQ QQKILVATES WYRQIIEYAP EGIMVLDAQG NIILANTSIE 300
  301 KLFGYSQTEL IGQSIALLGL AELLQQSLHL LQEGEDVGPT CPLDQEEFEI LGTRYDGSEF 360
  361 PIEVSLTSLP SLSQREMNIF ASVRDISARQ EAQQQILRQR EHLQSVLDSA PVGVAITVNG 420
  421 ITQFANPHIG ELVDLKVGDS PQKIYVDLGD RQQMLEELTQ FGRSQSRVYK MYNPRGEIRD 480
  481 ILATFLATDY EGQKGILGWL ADITPIKAAE AEMKRAKELA EEASRIKADF LANMSHEIRT 540
  541 PMNAVIGMTH LALKTDLTPR QREYLHKIRF SGQHLLGVIN DILDFSKIEA GKLPMESIDF 600
  601 DLDKVLDNVA TLISEKATNK GLELLFDIDR NLPRHFIGDP LRLGQILINY ANNAVKFTEQ 660
  661 GDITIVVRLQ EYRDQDVVLY LAVKDTGIGI KPEHIANLFN SFQQADSSTT RNFGGTGLGL 720
  721 AICKRIAELM GGEVGVESEY GQGSTFWAKV CLQKSNVIPH RLVLSKDLEG KRVLVVDDND 780
  781 HARLVMKDLL EQMKFVVETV ESGPEALNFL AEADRENHPH SIVFIDWQMP NMDGLEVARR 840
  841 LKAMGLNHQP SIFIVTAYGR EELFVKAKSL GIDDVLVKPI SPSVLFDSLA RVLGDPTALA 900
  901 QEMRQSSGIG AEDLALEKLR RIRGARILLV EDNEINQEVA AELLRDVGFN VDVAANGLIA 960
  961 LERLNNNAYA LVLMDMQMPE MDGIEATIAI RQNPRYAQLP IVAMTANVMQ GDRERCLQAG1020
 1021 MNDHLGKPIE PEELWNKLLH WIPVDSPLAP ETIEESAINT SDPEISIPHI PGLNSDDGLR1080
 1081 RVLGKKSLYL KMLHKFVASQ SSFLPEITQA LGEKDYGFAE RLAHTLKGVA GNIGAQELQQ1140
 1141 EAAELEKAIK EQWPQPEVEN LLTNLGDRLD NLIAQLTSNL PPEPATVAIT LDQGQLEEIC1200
 1201 DHLAQLLGED DAEAADLLQN HGDLLRQAFP DHYSAIAAGI NNFDFEAALA ALTTARQFSQ1260
 1261 P

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] Pfam 24.055517 No description for PF03707.7 was found. No confident structure predictions are available.
    2 View Details [141..242] Pfam 22.251812 No description for PF03707.7 was found. No confident structure predictions are available.
    3 View Details [243..434] FFAS03 4.88 Crystal Structure of the heme PAS sensor domain of Ec DOS (ferric form)
    4 View Details [435..511] deduced N/A No confident structure predictions are available.
    5 View Details [512..757] PSI-BLAST 44.0 Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
    6 View Details [758..909] PSI-BLAST 27.522879 Response regulator PleD in complex with c-diGMP
    7 View Details [910..1261] PSI-BLAST 59.522879 Crystal structure of sigm54 activator (AAA+ ATPase) in the inactive state

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • ion transmembrane transporter activity
    		•  1.81312487233411 bayes_pls_golite062009
  • binding
    		•  1.67984576110273 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.60314341650446 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.41577088905201 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.40823491489039 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  1.10325694432704 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.931375605669218 bayes_pls_golite062009
  • protein binding
    		•  0.888256242702267 bayes_pls_golite062009
  • voltage-gated ion channel activity
    		•  0.563198063703829 bayes_pls_golite062009
  • potassium channel activity
    		•  0.563028071397075 bayes_pls_golite062009
  • voltage-gated channel activity
    		•  0.552480950289765 bayes_pls_golite062009
  • voltage-gated cation channel activity
    		•  0.551619757281389 bayes_pls_golite062009
  • DNA binding
    		•  0.533187513797767 bayes_pls_golite062009
  • voltage-gated potassium channel activity
    		•  0.532581714382914 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.510719075994398 bayes_pls_golite062009
  • ion channel activity
    		•  0.483348490364346 bayes_pls_golite062009
  • two-component sensor activity
    		•  0.466388018187262 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  0.452475261443277 bayes_pls_golite062009
  • cation channel activity
    		•  0.445728116294453 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  0.409938237891918 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.391671932145714 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.388177774524707 bayes_pls_golite062009
  • channel activity
    		•  0.388177774524707 bayes_pls_golite062009
  • gated channel activity
    		•  0.383085563903689 bayes_pls_golite062009
  • signal transducer activity
    		•  0.341738261779128 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.341738261779128 bayes_pls_golite062009
  • catalytic activity
    		•  0.335650048048265 bayes_pls_golite062009
  • transporter activity
    		•  0.308330515689802 bayes_pls_golite062009
  • transcription factor activity
    		•  0.15709070306709 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.154730712374367 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • two-component response regulator activity
    		•  7.02872640261738 bayes_pls_golite062009
  • signal transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.51666042720644 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.44888100104099 bayes_pls_golite062009
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • binding
    		•  1.22427537074115 bayes_pls_golite062009
  • DNA binding
    		•  1.11037597107903 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05519146337499 bayes_pls_golite062009
  • protein kinase activity
    		•  1.00737355751913 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.811771244977462 bayes_pls_golite062009
  • kinase activity
    		•  0.725824770559857 bayes_pls_golite062009
  • transcription factor activity
    		•  0.62886970109503 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.476057209677045 bayes_pls_golite062009
    7
    Term Confidence Notes
  • protein histidine kinase activity
    		•  2.35011582062573 bayes_pls_golite062009
  • two-component sensor activity
    		•  2.32303301074957 bayes_pls_golite062009
  • phosphotransferase activity, nitrogenous group as acceptor
    		•  2.28838869071567 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.95073642969863 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.91141407779641 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.9017593265179 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.90014393273511 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  1.84572377553607 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  1.608578860823 bayes_pls_golite062009
  • transporter activity
    		•  1.55572428045529 bayes_pls_golite062009
  • anion transmembrane-transporting ATPase activity
    		•  1.49339466967388 bayes_pls_golite062009
  • ATPase activity
    		•  1.48474288797022 bayes_pls_golite062009
  • two-component response regulator activity
    		•  1.45919623810582 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.38483976298883 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  1.37457738689583 bayes_pls_golite062009
  • catalytic activity
    		•  1.37148167194523 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  1.3654237778347 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.32358677895008 bayes_pls_golite062009
  • binding
    		•  1.30574971150356 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.24278046928678 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.22440281711103 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  1.2014318795788 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  1.19670408144267 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  1.17063957238561 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  1.16918853509059 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  1.16885789920943 bayes_pls_golite062009
  • hydrolase activity
    		•  1.09839981963412 bayes_pls_golite062009
  • phosphate transmembrane-transporting ATPase activity
    		•  1.05293225786874 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.92950870381166 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.9275205656455 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.91280662021456 bayes_pls_golite062009
  • nucleotide binding
    		•  0.90809801369052 bayes_pls_golite062009
  • ATP binding
    		•  0.59269193555886 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.575892074401446 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.57504013359401 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.54853610492983 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  0.139527952740579 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.0838665746103899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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