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Protein Overview: XPB2_ARATH

General Information:
Name(s) found: XPB2_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • DNA repair helicase XPB2 OS=Arabidopsis thaliana GN=XPB2 PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 766 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to UV-B [IEP]
    Molecular Function: nucleic acid binding [IEA]
    DNA binding [IEA]
    ATP binding [IEA]
    ATP-dependent helicase activity [ISS]
    helicase activity [IEA]
    ATP-dependent DNA helicase activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNDERKRPT KKMKYGGKDD QKMKNIQNVE DYYDDADEDS RDGEGEEKRR DFTDLELKPD  60
   61 HGNRPLWACA DGKIFLETFS PLYKQAYDFL IAIAEPVCRP ESMHEYNLTP HSLYAAVSVG 120
  121 LETETIISVL NKLSKTKLPG EIIDFIHAST ANYGKVKLVL KKNRYFIESP FPEVLKRLLS 180
  181 DDVINRARFT SEPYYGGDGF TIGKTSGELE AGPGELLNEA ELAAAAEEKE THSFEIDPAL 240
  241 VENVKQRCLP NALNYPMLEE YDFRNDNVNP DLDMELKPHA QPRPYQEKSL SKMFGNGRAR 300
  301 SGIIVLPCGA GKSLVGVSAA ARIKKSCLCL ATNAVSVDQW AYQFKLWSTI KDDQICRFTS 360
  361 DSKERFRGNA GVVVTTYNMI AFGGKRSEEA EKIIEEMRNR EWGLLLMDEV HVVPAHMFRK 420
  421 VISITKSHCK LGLTATLVRE DEKITDLNFL IGPKLYEANW LDLVKGGFIA NVQCAEVWCP 480
  481 MTKEFFAEYL KKENSKKKQA LYVMNPNKFR ACEFLIRFHE QQRGDKIIVF ADNLFALTEY 540
  541 AMKLRKPMIY GATSHIERTK ILEAFKTSKT VNTVFLSKVG DNSIDIPEAN VIIQISSHAG 600
  601 SRRQEAQRLG RILRAKGKLE DRMAGGKEEY NAFFYSLVST DTQEMYYSTK RQQFLIDQGY 660
  661 SFKVITSLPP PDAGSSLGYH SQEEQLSLLG KVLNAGDDMV GLEQLEEDTD GKALKTRRSM 720
  721 GSMSAMSGAN GRVYMEYNSG RQKSGNQSKK PKDPTKRHNI FKKRYV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..138] deduced N/A No confident structure predictions are available.
    2 View Details [139..766] PSI-BLAST 56.522879 Crystal structure of Escherichia coli transcription-repair coupling factor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • general RNA polymerase II transcription factor activity
    		•  5.47805400577115 bayes_pls_golite062009
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
    		•  4.24230705019135 bayes_pls_golite062009
  • dATP binding
    		•  3.90236137621968 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.27883517727923 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.1445172484282 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.99059500119562 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • adenyl deoxyribonucleotide binding
    		•  2.90098016780049 bayes_pls_golite062009
  • purine deoxyribonucleotide binding
    		•  2.90098016780049 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  2.72222787956584 bayes_pls_golite062009
  • binding
    		•  2.64537357529343 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  2.60873257753475 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • hydrolase activity
    		•  2.55157966585974 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.51683451033161 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • DNA binding
    		•  2.12258000781149 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.09345198747025 bayes_pls_golite062009
  • endonuclease activity
    		•  1.96689197136388 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.85943679361938 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.85937484083653 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.8521191028835 bayes_pls_golite062009
  • nucleotide binding
    		•  1.84603132945448 bayes_pls_golite062009
  • helicase activity
    		•  1.70242731830224 bayes_pls_golite062009
  • ATP binding
    		•  1.5859264197035 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.55520429131224 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.53158018507951 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.2539059700735 bayes_pls_golite062009
  • protein binding
    		•  1.22129154759482 bayes_pls_golite062009
  • kinase activity
    		•  1.21578538537164 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.2155186842031 bayes_pls_golite062009
  • purine NTP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent helicase activity
    		•  1.19311444180077 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  1.18669029764243 bayes_pls_golite062009
  • protein kinase activity
    		•  1.12864835254143 bayes_pls_golite062009
  • double-stranded DNA binding
    		•  1.117585097627 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.11383295816593 bayes_pls_golite062009
  • catalytic activity
    		•  1.00104173493322 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • transcription activator activity
    		•  0.889929694023098 bayes_pls_golite062009
  • transcription factor activity
    		•  0.887108427603557 bayes_pls_golite062009
  • motor activity
    		•  0.87979065815418 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.72881469450553 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.579884353047732 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  0.568457189190858 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.543891899378373 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • microtubule motor activity
    		•  0.35554075339843 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.345873656782869 bayes_pls_golite062009
  • mismatched DNA binding
    		•  0.31144582840038 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • DNA strand annealing activity
    		•  0.283577486331079 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.243902356228423 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • RNA helicase activity
    		•  0.18426050934025 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.181509771587324 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • transferase activity
    		•  0.168270793917772 bayes_pls_golite062009
  • RNA-dependent ATPase activity
    		•  0.14606996093053 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.132012746266431 bayes_pls_golite062009
  • ATP-dependent RNA helicase activity
    		•  0.13050483816765 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.121792392568515 bayes_pls_golite062009
  • GTP binding
    		•  0.119757493758508 bayes_pls_golite062009
  • GTPase activity
    		•  0.105546189348878 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.0263010404932493 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle