YRC Public Data Repository - Protein Structure Prediction

Protein:	YFIQ_ECOLI
Organism:	Escherichia coli
Length:	886 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YFIQ_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|197361461, gi... - gi\|197361461\|ref\|YP_002141097.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica s... gi\|56412526, gi\|... - gi\|56412526\|ref\|YP_149601.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica serov... gi\|194401286, gi... - gi\|194442623\|ref\|YP_002041918.1\| CoA binding domain/acetyltransferase domain protein [Salmonella ent...	599.0	[0..1]	[886..1]
gi\|194408092, gi... - gi\|194449788\|ref\|YP_002046660.1\| CoA binding domain/acetyltransferase domain protein [Salmonella ent... gi\|168245085, gi... - gi\|205336131\|gb\|EDZ22895.1\| CoA binding domain/acetyltransferase domain protein [Salmonella enterica... lcl\|NC_016856.1_... - [gene=yfiQ] [protein=putative acetyl-CoA synthetase] [protein_id=YP_005238773.1] [location=2843714..... gi\|195628872, gi... - gi\|195628872\|gb\|EDX48286.1\| CoA binding domain/acetyltransferase domain protein [Salmonella enterica... gi\|161612629, gi... - gi\|161612629\|ref\|YP_001586594.1\| hypothetical protein SPAB_00324 [Salmonella enterica subsp. enteric... LYSAC_SALTY - Protein lysine acetyltransferase Pat OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)...	596.0	[0..1]	[886..1]
gi\|62128859, gi\|... - gi\|62181226\|ref\|YP_217643.1\| putative acetyl-CoA synthetase [Salmonella enterica subsp. enterica ser...	596.0	[0..1]	[886..1]
gi\|214000649 - gi\|214000649\|ref\|ZP_03411384.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica se... gi\|16761509 - gi\|16761509\|ref\|NP_457126.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica serov... gi\|213425260 - gi\|213425260\|ref\|ZP_03358010.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica se... gi\|25512315, gi\|... - gi\|25512315\|pir\|\|AD0831 probable acyl-CoA synthetase STY2844 [imported] - Salmonella enterica subsp.... gi\|29140794, gi\|... - gi\|29140794\|ref\|NP_804136.1\| putative acyl-CoA synthetase [Salmonella enterica subsp. enterica serov...	596.0	[0..1]	[886..1]
gi\|110616076, gi... - gi\|110806528\|ref\|YP_690048.1\| hypothetical protein SFV_2647 [Shigella flexneri 5 str. 8401], gi\|1106...	594.0	[0..1]	[886..1]
gi\|168773486, gi... - gi\|187770740\|gb\|EDU34584.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|189003230, gi... - gi\|189003230\|gb\|EDU72216.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|188013994, gi... - gi\|188013994\|gb\|EDU52116.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|168768690, gi... - gi\|189362335\|gb\|EDU80754.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|209400567, gi... - gi\|209400567\|ref\|YP_002272059.1\| acetyltransferase, GNAT family protein [Escherichia coli O157:H7 st... gi\|217327406, gi... - gi\|217327406\|ref\|ZP_03443489.1\| acetyltransferase, GNAT family protein [Escherichia coli O157:H7 str... gi\|12517006, gi\|... - gi\|15803112\|ref\|NP_289143.1\| hypothetical protein Z3869 [Escherichia coli O157:H7 EDL933], gi\|125170... gi\|208812815, gi... - gi\|208812815\|ref\|ZP_03254144.1\| acetyltransferase, GNAT family protein [Escherichia coli O157:H7 str... gi\|25495659 - pir\|\|A85905 hypothetical protein yfiQ [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|208819903, gi... - gi\|208819903\|ref\|ZP_03260223.1\| acetyltransferase, GNAT family protein [Escherichia coli O157:H7 str... gi\|195936732 - gi\|195936732\|ref\|ZP_03082114.1\| hypothetical protein EscherichcoliO157_09760 [Escherichia coli O157:... gi\|208728116, gi... - gi\|208808315\|ref\|ZP_03250652.1\| acetyltransferase, GNAT family protein [Escherichia coli O157:H7 str... gi\|189370148, gi... - gi\|189370148\|gb\|EDU88564.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|189376180, gi... - gi\|189376180\|gb\|EDU94596.1\| CoA binding domain/acetyltransferase domain protein [Escherichia coli O1... gi\|254593936, gi... - gi\|254794536\|ref\|YP_003079373.1\| predicted acyl-CoA synthetase: NAD(P)-binding subunit and ATP-bindi...	594.0	[0..1]	[886..1]
gi\|75178184, gi\|... - gi\|75178184\|ref\|ZP_00698243.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Shigella boydii BS512], g... gi\|81246450, gi\|... - gi\|82545039\|ref\|YP_408986.1\| hypothetical protein SBO_2616 [Shigella boydii Sb227], gi\|81246450\|gb\|A...	594.0	[0..1]	[886..1]
gi\|24053028, gi\|... - gi\|24113925\|ref\|NP_708435.1\| hypothetical protein SF2646 [Shigella flexneri 2a str. 301], gi\|2405302... gi\|30042241, gi\|... - gi\|30063985\|ref\|NP_838156.1\| hypothetical protein S2819 [Shigella flexneri 2a str. 2457T], gi\|300422...	594.0	[0..1]	[886..1]
gi\|193068407, gi... - gi\|75237670\|ref\|ZP_00721686.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Escherichia coli E110019]... gi\|191167989, gi... - gi\|75228841\|ref\|ZP_00715442.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Escherichia coli B7A], gi... gi\|194429281, gi... - gi\|75209517\|ref\|ZP_00709742.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Escherichia coli B171], g... gi\|157079284, gi... - gi\|75187337\|ref\|ZP_00700604.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Escherichia coli E24377A]...	594.0	[0..1]	[886..1]
gi\|75258009, gi\|... - gi\|75258009\|ref\|ZP_00729483.1\| COG1042: Acyl-CoA synthetase (NDP forming) [Escherichia coli E22], gi...	592.0	[0..1]	[886..1]

Back

Predicted Domain #1

Region A:
Residues: [1-60]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQRGLEALL RPKSIAVIGA SMKPNRAGYL MMRNLLAGGF NGPVLPVTPA WKAVLGVLAW  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	96.522879
Match:	2csuA
Description:	No description for 2csuA was found.

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.03099072397093	bayes_pls_golite062009
oxidoreductase activity	0.442294542097958	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [61-343]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDIASLPFTP DLAVLCTNAS RNLALLEELG EKGCKTCIIL SAPASQHEDL RACALRHNMR  60
   61 LLGPNSLGLL APWQGLNASF SPVPIKRGKL AFISQSAAVS NTILDWAQQR KMGFSYFIAL 120
  121 GDSLDIDVDE LLDYLARDSK TSAILLYLEQ LSDARRFVSA ARSASRNKPI LVIKSGRSPA 180
  181 AQRLLNTTAG MDPAWDAAIQ RAGLLRVQDT HELFSAVETL SHMRPLRGDR LMIISNGAAP 240
  241 AALALDALWS RNGKLATLSE ETCQKLRDAL PEHVAISNPL DLR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	38.69897
Match:	1jkjB
Description:	Succinyl-CoA synthetase, beta-chain, C-terminal domain; Succinyl-CoA synthetase, beta-chain, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ligase activity	2.65834437588388	bayes_pls_golite062009
catalytic activity	2.5009559386228	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	2.03020006934407	bayes_pls_golite062009
CoA carboxylase activity	1.97356692026797	bayes_pls_golite062009
succinate-CoA ligase activity	1.97320026759321	bayes_pls_golite062009
CoA-ligase activity	1.70650205723619	bayes_pls_golite062009
acid-thiol ligase activity	1.65304911485061	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	1.55053478055591	bayes_pls_golite062009
acetyl-CoA carboxylase activity	1.47371551641074	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	1.34583813987229	bayes_pls_golite062009
biotin carboxylase activity	0.434630727705062	bayes_pls_golite062009
acid-amino acid ligase activity	0.311469287876404	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.239594107637156	bayes_pls_golite062009
glutathione synthase activity	0.158287661667506	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [344-446]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDASSEHYIK TLDILLHSQD FDALMVIHSP SAAAPATESA QVLIEAVKHH PRSKYVSLLT  60
   61 NWCGEHSSQE ARRLFSEAGL PTYRTPEGTI TAFMHMVEYR RNQ

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	3.18
Match:	2csuA
Description:	No description for 2csuA was found.

Predicted functions:

Term	Confidence	Notes
succinate-CoA ligase activity	3.52802052141868	bayes_pls_golite062009
CoA-ligase activity	3.32683490551571	bayes_pls_golite062009
acid-thiol ligase activity	3.31605458365624	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	3.04561299684894	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	2.98693702730095	bayes_pls_golite062009
catalytic activity	1.7583229741529	bayes_pls_golite062009
ligase activity	1.3838037949679	bayes_pls_golite062009
ATP citrate synthase activity	1.05845534244237	bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	0.16119750312318	bayes_pls_golite062009

Predicted Domain #4

Region A:
Residues: [447-699]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KQLRETPALP SNLTSNTAEA HLLLQQAIAE GATSLDTHEV QPILQAYGMN TLPTWIASDS  60
   61 TEAVHIAEQI GYPVALKLRS PDIPHKSEVQ GVMLYLRTAN EVQQAANAIF DRVKMAWPQA 120
  121 RVHGLLVQSM ANRAGAQELR VVVEHDPVFG PLIMLGEGGV EWRPEDQAVV ALPPLNMNLA 180
  181 RYLVIQGIKS KKIRARSALR PLDVAGLSQL LVQVSNLIVD CPEIQRLDIH PLLASGSEFT 240
  241 ALDVTLDISP FEG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.69897
Match:	1wr2A
Description:	Crystal structure of PH1788 from Pyrococcus horikoshii Ot3
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [700-886]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DNESRLAVRP YPHQLEEWVE LKNGERCLFR PILPEDEPQL QQFISRVTKE DLYYRYFSEI  60
   61 NEFTHEDLAN MTQIDYDREM AFVAVRRIDQ TEEILGVTRA ISDPDNIDAE FAVLVRSDLK 120
  121 GLGLGRRLME KLITYTRDHG LQRLNGITMP NNRGMVALAR KLGFNVDIQL EEGIVGLTLN 180
  181 LAQREES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.0
Match:	2fe7A
Description:	The crystal structure of a probable N-acetyltransferase from Pseudomonas aeruginosa
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetyltransferase activity	3.80196053262573	bayes_pls_golite062009
acyltransferase activity	3.60905247184823	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.57844985672878	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.17094374417123	bayes_pls_golite062009
catalytic activity	1.97933499002461	bayes_pls_golite062009
transferase activity	1.72447231774431	bayes_pls_golite062009
N-acyltransferase activity	0.890897647236405	bayes_pls_golite062009
N-acetyltransferase activity	0.498634717186713	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions:

Predicted functions:

Predicted functions: