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View Structure Prediction Details

Protein: RAN_PLAFA
Organism: Plasmodium falciparum
Length: 214 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAN_PLAFA.

Description E-value Query
Range		 Subject
Range
gi|1616614 - gi|1616614|emb|CAA69701.1| small GTP-binding protein [Nicotiana plumbaginifolia]
 234.0 [0..3] [207..2]
gi|37360618 - gi|37360618|dbj|BAC98287.1| mKIAA3012 protein [Mus musculus]
 234.0 [0..1] [205..49]
gi|61365844, gi|... - gi|61365844|gb|AAX42772.1| RAB1A member RAS oncogene family [synthetic construct], gi|54695924|gb|AA...
 234.0 [0..1] [207..1]
rab-1 - RAS-related protein status:Confirmed UniProt:Q9UAQ6 protein_id:AAC69218.1
 232.0 [0..1] [205..1]
CRE16067, FL81_1... - RP15185 WBGene00061078 locus:Cre-rab-1 status:Confirmed, null
gi|157761211 - gi|157761211|ref|XP_001672948.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae AF16]
gi|39588485, gi|... - gi|39588485|emb|CAE58008.1| Hypothetical protein CBG01077 [Caenorhabditis briggsae], gi|187038224|em...
 232.0 [0..1] [205..1]
gi|50738954 - gi|50738954|ref|XP_419342.1| PREDICTED: similar to ras-related protein [Gallus gallus]
 232.0 [0..7] [205..197]
gi|53733986 - gb|AAH83951.1| Unknown (protein for MGC:97957) [Xenopus laevis]
gi|55741705 - ref|NP_001003153.1| RAB1A, member RAS oncogene family [Canis familiaris]
gi|120419448, gi... - gi|76629653|ref|XP_869337.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 2 [Bos t...
gi|109103156 - gi|109103156|ref|XP_001090072.1| PREDICTED: similar to RAB1, member RAS oncogene family isoform 4 [M...
gi|61355917, gi|... - gi|61355926|gb|AAX41191.1| RAB1A member RAS oncogene family [synthetic construct], gi|61355917|gb|AA...
tr|G1TCS8|G1TCS8... - pep:novel chromosome:oryCun2:2:121177308:121212010:1 gene:ENSOCUG00000017003 transcript:ENSOCUT00000...
RAB1A - RAB1A, member RAS oncogene family
RAB1A_RAT - Ras-related protein Rab-1A OS=Rattus norvegicus GN=Rab1A PE=1 SV=3
RAB1A_CANLF - Ras-related protein Rab-1A OS=Canis lupus familiaris GN=RAB1A PE=1 SV=3
gi|159906367 - gi|159906367|gb|ABX10872.1| RAB1A [Capra hircus]
RAB1A_MOUSE - Ras-related protein Rab-1A OS=Mus musculus GN=Rab1A PE=1 SV=3
tr|M3VYP9|M3VYP9... - RAB1A, member RAS oncogene family OS=Felis catus GN=RAB1A PE=4 SV=1
gi|149727528 - gi|149727528|ref|XP_001493347.1| PREDICTED: similar to RAB1A, member RAS oncogene family [Equus caba...
 231.0 [0..1] [205..1]
gi|7643790 - gi|7643790|gb|AAF65510.1| small GTP-binding protein [Capsicum annuum]
 231.0 [0..3] [205..2]
ARA5_ARATH - Ras-related protein ARA-5 - Arabidopsis thaliana (Mouse-ear cress)
 231.0 [0..3] [205..57]
gi|1053067 - gi|1053067|gb|AAA80680.1| small GTP-binding protein
 230.0 [0..3] [205..2]

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Predicted Domain #1
Region A:
Residues: [1-214] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSQEYIPQY KLILVGDGGV GKTTFVKRHL TGEFEKKYIP TLGVEVHPLK FQTNFGKTQF  60
   61 NVWDTAGQEK FGGLRDGYYI KSDCAIIMFD VSSRITYKNV PNWYRDITRV CETIPMVLVG 120
  121 NKVDVKDRQV KSRQIQFHRK RNLQYYDLSA RSNYNFEKPF LWLARRLSNQ PNLVFVGEHA 180
  181 KAPEFQIDLN IVREAEKELE QAAAVAIDEE DIEN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 51.045757
Match: 1byuA
Description: Ran
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 4.51968578934603 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
DNA-dependent ATPase activity 2.72462789867829 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
hydrolase activity 2.65461298232951 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
microfilament motor activity 2.51786963027655 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
G-protein coupled receptor activity 2.3505608190884 bayes_pls_golite062009
protein-DNA loading ATPase activity 2.29933364503114 bayes_pls_golite062009
actin binding 2.2973522188675 bayes_pls_golite062009
DNA helicase activity 2.2817164193758 bayes_pls_golite062009
DNA clamp loader activity 2.25735202908071 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
ATP-dependent DNA helicase activity 1.88455339138556 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
purine ribonucleotide binding 1.85943679361938 bayes_pls_golite062009
ribonucleotide binding 1.85937484083653 bayes_pls_golite062009
purine nucleotide binding 1.8521191028835 bayes_pls_golite062009
nucleotide binding 1.84603132945448 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.81972511638668 bayes_pls_golite062009
kinase activity 1.80889641165674 bayes_pls_golite062009
protein transporter activity 1.71214667007262 bayes_pls_golite062009
helicase activity 1.70242731830224 bayes_pls_golite062009
GTPase activity 1.6309422514633 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.60386625568858 bayes_pls_golite062009
ATP binding 1.5859264197035 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
adenyl ribonucleotide binding 1.55520429131224 bayes_pls_golite062009
adenyl nucleotide binding 1.53158018507951 bayes_pls_golite062009
apolipoprotein receptor activity 1.52496551152043 bayes_pls_golite062009
syntaxin-13 binding 1.52496551152043 bayes_pls_golite062009
apolipoprotein A-I binding 1.52496551152043 bayes_pls_golite062009
apolipoprotein A-I receptor activity 1.52496551152043 bayes_pls_golite062009
signal recognition particle binding 1.46975774710831 bayes_pls_golite062009
RNA helicase activity 1.42791449104435 bayes_pls_golite062009
RNA-dependent ATPase activity 1.39335733374328 bayes_pls_golite062009
plus-end-directed microtubule motor activity 1.38366133153678 bayes_pls_golite062009
ATP-dependent RNA helicase activity 1.36724390116598 bayes_pls_golite062009
actin filament binding 1.28204719195916 bayes_pls_golite062009
transmembrane receptor activity 1.26314334516725 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
receptor activity 1.20313362488821 bayes_pls_golite062009
ATP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
purine NTP-dependent helicase activity 1.19311444180077 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 1.14475274823167 bayes_pls_golite062009
signal transducer activity 1.13474466330485 bayes_pls_golite062009
molecular transducer activity 1.13474466330485 bayes_pls_golite062009
protein kinase activity 1.12864835254143 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.11794390756322 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
DNA-directed DNA polymerase activity 0.971476020912368 bayes_pls_golite062009
DNA polymerase activity 0.928091843881235 bayes_pls_golite062009
actin-dependent ATPase activity 0.92105578610354 bayes_pls_golite062009
transcription activator activity 0.889929694023098 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 0.889480122725603 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
transferase activity 0.871779313294914 bayes_pls_golite062009
structure-specific DNA binding 0.782430219754236 bayes_pls_golite062009
microtubule plus-end binding 0.673980113049624 bayes_pls_golite062009
steroid hormone receptor binding 0.647625526012423 bayes_pls_golite062009
double-stranded DNA binding 0.6071273686445 bayes_pls_golite062009
telomeric DNA binding 0.60010060632866 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
sequence-specific DNA binding 0.543891899378373 bayes_pls_golite062009
ribonucleoprotein binding 0.53788302029845 bayes_pls_golite062009
kinetochore binding 0.505370954958131 bayes_pls_golite062009
protein transmembrane transporter activity 0.46552249844591 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.444874730945263 bayes_pls_golite062009
0.442119153778711 bayes_pls_golite062009
hormone receptor binding 0.351501100511918 bayes_pls_golite062009
protein serine/threonine kinase activity 0.345873656782869 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 0.325013574811283 bayes_pls_golite062009
peptide binding 0.304703625340488 bayes_pls_golite062009
DNA strand annealing activity 0.270268254152179 bayes_pls_golite062009
nuclear hormone receptor binding 0.246160342138071 bayes_pls_golite062009
structural constituent of ribosome 0.208665086324262 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 0.12351419478929 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
structural constituent of muscle 0.0436357112276422 bayes_pls_golite062009
histone acetyltransferase activity 0.0320943071400439 bayes_pls_golite062009
lysine N-acetyltransferase activity 0.0320943071400439 bayes_pls_golite062009
RNA binding 0.0261282189186349 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009
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Created and Maintained by: Michael Riffle