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View Structure Prediction Details

Protein: CUL2_ARATH
Organism: Arabidopsis thaliana
Length: 742 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CUL2_ARATH.

Description E-value Query
Range
Subject
Range
gi|40788303 - gi|40788303|dbj|BAA31592.2| KIAA0617 protein [Homo sapiens]
689.0 [0..1] [742..41]

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Predicted Domain #1
Region A:
Residues: [1-742]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKKDSVLEA GWSVMEAGVA KLQKILEEVP DEPPFDPVQR MQLYTTVHNL CTQKPPNDYS  60
   61 QQIYDRYGGV YVDYNKQTVL PAIREKHGEY MLRELVKRWA NQKILVRWLS HFFEYLDRFY 120
  121 TRRGSHPTLS AVGFISFRDL VYQELQSKAK DAVLALIHKE REGEQIDRAL LKNVIDVYCG 180
  181 NGMGELVKYE EDFESFLLED SASYYSRNAS RWNQENSCPD YMIKAEESLR LEKERVTNYL 240
  241 HSTTEPKLVA KVQNELLVVV AKQLIENEHS GCRALLRDDK MDDLARMYRL YHPIPQGLDP 300
  301 VADLFKQHIT VEGSALIKQA TEAATDKAAS TSGLKVQDQV LIRQLIDLHD KFMVYVDECF 360
  361 QKHSLFHKAL KEAFEVFCNK TVAGVSSAEI LATYCDNILK TGGGIEKLEN EDLELTLEKV 420
  421 VKLLVYISDK DLFAEFFRKK QARRLLFDRN GNDYHERSLL TKFKELLGAQ FTSKMEGMLT 480
  481 DMTLAKEHQT NFVEFLSVNK TKKLGMDFTV TVLTTGFWPS YKTTDLNLPI EMVNCVEAFK 540
  541 AYYGTKTNSR RLSWIYSLGT CQLAGKFDKK TIEIVVTTYQ AAVLLLFNNT ERLSYTEILE 600
  601 QLNLGHEDLA RLLHSLSCLK YKILIKEPMS RNISNTDTFE FNSKFTDKMR RIRVPLPPMD 660
  661 ERKKIVEDVD KDRRYAIDAA LVRIMKSRKV LGHQQLVSEC VEHLSKMFKP DIKMIKKRIE 720
  721 DLISRDYLER DTDNPNTFKY LA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2hyeC
Description: No description for 2hyeC was found.

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 9.47178230940453 bayes_pls_golite062009
small conjugating protein ligase activity 9.15192834197166 bayes_pls_golite062009
acid-amino acid ligase activity 8.12051073361876 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 6.87003086224111 bayes_pls_golite062009
transcription regulator activity 4.76121492612224 bayes_pls_golite062009
transcription factor activity 3.7855017556511 bayes_pls_golite062009
ligase activity 3.66453881539688 bayes_pls_golite062009
transcription repressor activity 2.39237599101586 bayes_pls_golite062009
binding 2.3219000606044 bayes_pls_golite062009
protein binding 2.20237620151495 bayes_pls_golite062009
vasopressin activated calcium mobilizing receptor activity 2.15618962838168 bayes_pls_golite062009
transcription activator activity 2.05043065144612 bayes_pls_golite062009
nucleic acid binding 1.54797684894025 bayes_pls_golite062009
DNA binding 1.42215436462553 bayes_pls_golite062009
RNA polymerase II transcription factor activity 1.23862224095769 bayes_pls_golite062009
transporter activity 0.891050405674973 bayes_pls_golite062009
transmembrane transporter activity 0.648150681919233 bayes_pls_golite062009
transcription factor binding 0.612315945412079 bayes_pls_golite062009
substrate-specific transporter activity 0.368917395770011 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.249771970501337 bayes_pls_golite062009
catalytic activity 0.201606344181603 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.146182977030285 bayes_pls_golite062009
hydrolase activity 0.140191206949582 bayes_pls_golite062009
structure-specific DNA binding 0.117670813298683 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.107671044044222 bayes_pls_golite062009
transferase activity 0.064832527337659 bayes_pls_golite062009
specific transcriptional repressor activity 0.0565989703351002 bayes_pls_golite062009
sequence-specific DNA binding 0.0102780098866235 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle