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View Structure Prediction Details

Protein: chn-1
Organism: Caenorhabditis elegans
Length: 266 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for chn-1.

Description E-value Query
Range
Subject
Range
gi|48892684, gi|... - gi|71675161|ref|ZP_00672907.1| Peptidase S1, chymotrypsin:TPR repeat [Trichodesmium erythraeum IMS10...
217.0 [0..2] [265..321]

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Predicted Domain #1
Region A:
Residues: [1-266]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGAEQHNT NGKKCYMNKR YDDAVDHYSK AIKVNPLPKY YQNRAMCYFQ LNNLKMTEED  60
   61 CKRALELSPN EVKPLYFLGN VFLQSKKYSE AISCLSKALY HNAVITNAPD IENALKRARH 120
  121 QKYEEEESKR IVQDVEFHTY LESLIEKDRQ ENSENPEELQ RADMAKKRLT ELTLATQEKR 180
  181 QNREVPEMLC GKITLELMKE PVIVPSGITY DREEIVQHLR RIGHFDPVTR KPLTENEIIP 240
  241 NYALKEVIEK FLDDNPWAKY EPGGMV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 2c2lA
Description: Crystal structure of the CHIP U-box E3 ubiquitin ligase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 5.97121728620188 bayes_pls_golite062009
small conjugating protein ligase activity 5.78935175140238 bayes_pls_golite062009
acid-amino acid ligase activity 4.75377804653841 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 3.82459130917693 bayes_pls_golite062009
protein binding 2.64803540957326 bayes_pls_golite062009
binding 2.14721962003828 bayes_pls_golite062009
SMAD binding 1.93335489484338 bayes_pls_golite062009
ubiquitin-ubiquitin ligase activity 1.37401357060257 bayes_pls_golite062009
heat shock protein binding 1.23450221149054 bayes_pls_golite062009
transcription regulator activity 1.15544062259083 bayes_pls_golite062009
unfolded protein binding 1.03065657981002 bayes_pls_golite062009
nucleic acid binding 0.952465452241625 bayes_pls_golite062009
small conjugating protein-specific protease activity 0.637551805535732 bayes_pls_golite062009
ligase activity 0.63517530468004 bayes_pls_golite062009
DNA binding 0.618808911370101 bayes_pls_golite062009
ubiquitin-specific protease activity 0.549461161056205 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides 0.212156557156054 bayes_pls_golite062009
peptidase activity 0.184055035984234 bayes_pls_golite062009
cysteine-type peptidase activity 0.159023519781458 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
transcription factor binding 0.12026866735209 bayes_pls_golite062009
transcription activator activity 0.031505858565037 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle