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View Structure Prediction Details

Protein: rpa-2
Organism: Caenorhabditis elegans
Length: 288 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rpa-2.

Description E-value Query
Range
Subject
Range
gi|114555089 - gi|114555089|ref|XP_513251.2| PREDICTED: similar to Replication protein A 32 kDa subunit (RP-A) (RF-...
280.0 [0..1] [287..129]

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Predicted Domain #1
Region A:
Residues: [1-288]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNETVEHEN AGNGWAAGES SFMTDRKPDS KATTLGERLP VPVTISNLIE HFSAQDDKYV  60
   61 VGTFRFATVL TVGIVKDISQ DGTTYTYDLC DPNNTEMEYR TLKYDNEGST FDHSSIVEGT 120
  121 RVRAIGKLKG FDGNNTIMLF NITPVEDDKD FTIFELEAEA ARLFFQKNVS EKLKSVDSDG 180
  181 FQGMLAPPKS RMSQTSHQSS QGSDTKERLY AQPQKVMTGA NQGDVLRERI TAVLMAVPEG 240
  241 SRDEGRHVSW IAEQIQETNI SIVRKCVGEM VENGLVYTTV DEETVSAI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.69897
Match: 2pi2A
Description: No description for 2pi2A was found.

Predicted functions:

Term Confidence Notes
single-stranded DNA binding 3.59212997362902 bayes_pls_golite062009
structure-specific DNA binding 3.53214384646348 bayes_pls_golite062009
nucleic acid binding 3.27576062206528 bayes_pls_golite062009
binding 2.63617204791771 bayes_pls_golite062009
DNA binding 2.56243510083541 bayes_pls_golite062009
ribonuclease activity 2.19009583193838 bayes_pls_golite062009
structural constituent of ribosome 2.13063800565247 bayes_pls_golite062009
structural molecule activity 1.9177190829469 bayes_pls_golite062009
telomeric DNA binding 1.7847835613194 bayes_pls_golite062009
single-stranded telomeric DNA binding 1.48033977789232 bayes_pls_golite062009
telomerase inhibitor activity 1.25988289474883 bayes_pls_golite062009
DNA helicase activity 1.12203697857261 bayes_pls_golite062009
exoribonuclease activity 1.07725510169091 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.05277881555112 bayes_pls_golite062009
DNA-directed RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
RNA polymerase activity 0.79554655100991 bayes_pls_golite062009
transcription regulator activity 0.756094573447167 bayes_pls_golite062009
hydrolase activity 0.724860465280978 bayes_pls_golite062009
DNA-dependent ATPase activity 0.638831894247026 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.592562824942671 bayes_pls_golite062009
nuclease activity 0.57381531077345 bayes_pls_golite062009
translation regulator activity 0.515576958825022 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.468402630523277 bayes_pls_golite062009
double-stranded DNA binding 0.378383789953688 bayes_pls_golite062009
nucleotidyltransferase activity 0.325774164899685 bayes_pls_golite062009
exonuclease activity 0.28313884527829 bayes_pls_golite062009
sequence-specific DNA binding 0.21650406007586 bayes_pls_golite062009
translation initiation factor activity 0.2080607201312 bayes_pls_golite062009
exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.0954216620147701 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 0.0909806857084046 bayes_pls_golite062009
transcription factor activity 0.0591886273075271 bayes_pls_golite062009
protein binding 0.0528188351789111 bayes_pls_golite062009
ATP-dependent DNA helicase activity 0.0179535526984695 bayes_pls_golite062009
helicase activity 0.0121541775159524 bayes_pls_golite062009

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