YRC Public Data Repository - Protein Structure Prediction

Protein:	pof9
Organism:	Schizosaccharomyces pombe
Length:	467 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pof9.

Description	E-value	Query Range	Subject Range
gi\|55250203 - gb\|AAH86223.1\| Unknown (protein for MGC:98711) [Xenopus laevis] gi\|74188723, gi\|... - gi\|74188723\|dbj\|BAE28095.1\| unnamed protein product [Mus musculus], gi\|32451488\|ref\|NP_080377.2\| hec...	299.0	[0..82]	[448..3]
HERC4_RAT - Probable E3 ubiquitin-protein ligase HERC4 OS=Rattus norvegicus GN=Herc4 PE=2 SV=1	298.0	[0..82]	[448..3]
gi\|114630756, gi... - gi\|114630758\|ref\|XP_001167783.1\| PREDICTED: hect domain and RLD 4 isoform 9 [Pan troglodytes], gi\|11...	297.0	[0..82]	[448..3]
gi\|91092286 - gi\|91092286\|ref\|XP_968558.1\| PREDICTED: similar to hect (homologous to the E6-AP (UBE3A) carboxyl te...	297.0	[0..75]	[431..2826]
gi\|73952751 - gi\|73952751\|ref\|XP_860006.1\| PREDICTED: similar to hect domain and RLD 4 isoform a isoform 9 [Canis ...	297.0	[0..82]	[421..3]
gi\|55957427, gi\|... - gi\|55957427\|emb\|CAI16032.1\| hect domain and RLD 4 [Homo sapiens], gi\|55663742\|emb\|CAH74148.1\| hect d...	296.0	[0..82]	[448..3]
gi\|110764378 - gi\|110764378\|ref\|XP_395007.3\| PREDICTED: similar to hect (homologous to the E6-AP (UBE3A) carboxyl t...	296.0	[0..80]	[424..2897]

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Predicted Domain #1

Region A:
Residues: [1-467]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKSPFLELS YDILLEISTY LDYKDIVHLS ETCKSLSYVF DDKTIWHRFC ARVQGLTNVV  60
   61 PVVDDNYKRP YAVWKDRGYA YSWGQQIRNY LGRVVNTNQY PRDRPGALTG KDVRSTIQVQ 120
  121 VGGYGMYLLN ENGNLYVTGV PNNVGPELMR DLEPIVKIHA GREFCLALGE TGHLYQVSLK 180
  181 TRICLTDEQN MLSAYRGRIA NFKSGWDSHS AYVPGIGFLV WHTGRESEAQ LFQPEASMKE 240
  241 FVLNDYVHCA GFLVYTVASP QKKGAVFRLD LDQATQHTLG RELKRFASHD PHQGWHLAGS 300
  301 FETFTCLSDD GNTVYMGHAN TKQVDDDPVI HDFLQNRGIK QLAHGDHHHL YLTSDHSIWS 360
  361 WGVELRYCGC LGLGSLHLQE QTSDPSIVSD PRTARNIVSI PHQIHFSGTC YSVAAGGWQS 420
  421 AALAISESVL PEVNVPPITT FSIIRPSRVP ALRFLAAPAT RTLERDG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	61.69897
Match:	1a12A
Description:	Regulator of chromosome condensation RCC1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ubiquitin-protein ligase activity	0.970497409952391	bayes_pls_golite062009
small conjugating protein ligase activity	0.968973276416404	bayes_pls_golite062009
acid-amino acid ligase activity	0.79389712729474	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.659968164974572	bayes_pls_golite062009
ligase activity	0.600903970798223	bayes_pls_golite062009
binding	0.569157611496849	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: