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View Structure Prediction Details

Protein: CG7609-PB
Organism: Drosophila melanogaster
Length: 776 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG7609-PB.

Description E-value Query
Range
Subject
Range
gi|148658115, gi... - gi|148658115|ref|YP_001278320.1| NB-ARC domain-containing protein [Roseiflexus sp. RS-1], gi|1485702...
675.0 [0..2] [718..760]

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Predicted Domain #1
Region A:
Residues: [1-580]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDSVEDTST ISLRICLEGH ANALALNKDN NQIALAGRSL LKVYSINSNG FTESCNMRGK  60
   61 NQNLSYSAND VAWSTLDSNL LATAATNGVV SVWDLSKFGR QKQLLVYNEH ERTAHTVTFH 120
  121 SSEPNILISG SQDGTIKCFD IRSDKSINTY FCNSESVRDV KFSPHTQNIF SAVSENGTVQ 180
  181 LWDMRKWDKC MVQFTAHYGP VYTCDWHPTR NWLATGSRDK QIKVWNMDGR PGLEHTIHTI 240
  241 AVVGRVKWRP ERTYHIASCA LVVDYSVHVW DIRRPYIPFA SFNEHTNVTT GIAWQGSDSH 300
  301 CLLSISKDST IYKHAFKDAT RPALKANAQG ASLGRFGDIS FANKIKEYEP KTSGASNTKS 360
  361 SSFIRRKTNV AGSIQFHLDH SKMYKFMVND TFSGYPLSES VSRPTQEHES FIGCARELVI 420
  421 SGKKLSELCE HNAEVSKKYG KHNATTLWNF IKLFYGSNHF EPPFEHRSSF SNQKNPMNSR 480
  481 RATQVASDWP QQRTELGQDL NGNTPETAHE IDVANVDDDT LGSSGVEHPP TSSVILSETQ 540
  541 IISEITFDNF ELLRNGFIYV GPTECPKALA FPALHHDVQA 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 55.39794
Match: 1nr0A
Description: Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
histone methyltransferase activity (H3-K4 specific) 4.71992275913384 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.25521258308263 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
transcription regulator activity 2.10348788067437 bayes_pls_golite062009
nucleic acid binding 2.00420268007946 bayes_pls_golite062009
histone methyltransferase activity 1.85632145559025 bayes_pls_golite062009
peroxisome targeting sequence binding 1.73465159850484 bayes_pls_golite062009
myosin heavy chain kinase activity 1.67241027239254 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.53722103498827 bayes_pls_golite062009
DNA binding 1.53482914288832 bayes_pls_golite062009
protein methyltransferase activity 1.35170368882651 bayes_pls_golite062009
cytoskeletal protein binding 1.26395898062853 bayes_pls_golite062009
lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
histone-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
protein-lysine N-methyltransferase activity 1.15313682561559 bayes_pls_golite062009
actin binding 1.08902852052152 bayes_pls_golite062009
myosin II binding 0.990046481880222 bayes_pls_golite062009
transcription factor activity 0.897833210520351 bayes_pls_golite062009
transcription activator activity 0.724420384084538 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
histone binding 0.685319917508843 bayes_pls_golite062009
transcription repressor activity 0.624053529462119 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
transcription factor binding 0.469377587704245 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.350063170588591 bayes_pls_golite062009
snoRNA binding 0.347797037104681 bayes_pls_golite062009
kinase activity 0.338000962379752 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.310954405547192 bayes_pls_golite062009
0.309947462700731 bayes_pls_golite062009
transcription cofactor activity 0.245000508226811 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
transcription corepressor activity 0.0676565515282608 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009
N-methyltransferase activity 0.00335766408304172 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [581-673]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARPQLDLKAS DHEKSPPPHV PTVLKVSHVP PIPMWEPHKF VSDALMLMND VGDVQTALTV  60
   61 LIALGEARKL LPIDDALVEH WFYTYVDQLH RYE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [674-776]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LWNEACEVIN RSWLRSVQQL NQHSTAMHTN CGECGRPMGG KVGWYCDKCK SMQSAKCCVC  60
   61 GLIVRGVYAW CQGCSHGGHI EHLQKYFAKH SKCPKCGHLC AYS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.11
Match: 1u6gB
Description: Crystal Structure of The Cand1-Cul1-Roc1 Complex
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.70912934275371 bayes_pls_golite062009
protein binding 2.53639372327734 bayes_pls_golite062009
transcription regulator activity 2.43550037810204 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 2.34249142154884 bayes_pls_golite062009
small conjugating protein ligase activity 2.19099740571398 bayes_pls_golite062009
ubiquitin-protein ligase activity 2.07850206021921 bayes_pls_golite062009
nucleic acid binding 2.00995305333938 bayes_pls_golite062009
DNA binding 1.83065139740537 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.71590168075775 bayes_pls_golite062009
acid-amino acid ligase activity 1.21656984446301 bayes_pls_golite062009
transcription factor activity 1.04235253972776 bayes_pls_golite062009
transcription factor binding 0.967386953279331 bayes_pls_golite062009
transcription activator activity 0.925421178530707 bayes_pls_golite062009
ligase activity 0.424146907469434 bayes_pls_golite062009
transcription repressor activity 0.249123241769561 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
transcription cofactor activity 0.0747635659870247 bayes_pls_golite062009
transcription coactivator activity 0.0710429693374812 bayes_pls_golite062009
enzyme binding 0.0252200602272163 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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