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View Structure Prediction Details

Protein: gi|7299843, gi|2...
Organism: Drosophila melanogaster
Length: 728 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7299843, gi|2....

Description E-value Query
Range
Subject
Range
Kif19A-PB - The gene Kif19A is referred to in FlyBase by the symbol Dmel\Kif19A (CG9913, FBgn0038205). It is a p...
350.0 [0..1] [728..1]

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Predicted Domain #1
Region A:
Residues: [1-369]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSAGASSW SGSSGGSNSS QGRSIATAQP AQEERLVVAV RVRPSMEATE RCIEVISGGS  60
   61 LLYDDGGKSR PRQYSYDHVF RENDSQEQVY KTTTAPLTHT MLGPVPRKKP QTSDRAPPTA 120
  121 SCDSTDVSSQ DIGLMVRAIE DIFSHIESAE AYSCRVSISY LEIYNELIRD LLNPGGPLEL 180
  181 REDHRGQRIT VAGLSEITTS SRKEVVSLLL KGNKARTMEP TAANQTSSRS HALLSIMVQA 240
  241 RTPLGTKQGR LFLTDLAGSE RAKKTKNRGK RLQEGAHINR SLLALGNVIN GLSGGARYVN 300
  301 YRDSKLTRLL KEALSGRCKT VMIAHVAPES KHRDETKNTL VYADRANSIT TKLQNSVYID 360
  361 EFKDFPTKH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 87.522879
Match: 1gojA
Description: Kinesin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
microtubule motor activity 7.68336791348661 bayes_pls_golite062009
plus-end-directed microtubule motor activity 4.97507344344589 bayes_pls_golite062009
microfilament motor activity 4.176620576177 bayes_pls_golite062009
motor activity 4.04927796049806 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
actin-dependent ATPase activity 2.77140616759165 bayes_pls_golite062009
tubulin binding 2.67743463093593 bayes_pls_golite062009
microtubule binding 2.59155206524122 bayes_pls_golite062009
transporter activity 2.58140740499725 bayes_pls_golite062009
binding 2.44689197844883 bayes_pls_golite062009
cytoskeletal protein binding 2.4101693596493 bayes_pls_golite062009
transmembrane transporter activity 2.39695871109024 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
ATPase activity, coupled 2.18396165590908 bayes_pls_golite062009
actin binding 1.75397031486306 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
microtubule plus-end binding 1.36713729043205 bayes_pls_golite062009
substrate-specific transporter activity 1.29730375126024 bayes_pls_golite062009
DNA-dependent ATPase activity 1.07479235523606 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.906554174337376 bayes_pls_golite062009
helicase activity 0.79055709374547 bayes_pls_golite062009
actin filament binding 0.728264616959762 bayes_pls_golite062009
nucleic acid binding 0.574285918029279 bayes_pls_golite062009
GTPase activity 0.437665353870877 bayes_pls_golite062009
active transmembrane transporter activity 0.434775387083003 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
guanyl nucleotide binding 0.399434758448606 bayes_pls_golite062009
GTP binding 0.398333597279278 bayes_pls_golite062009
guanyl ribonucleotide binding 0.39332178627529 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
ion transmembrane transporter activity 0.355466224802969 bayes_pls_golite062009
primary active transmembrane transporter activity 0.294474570607914 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.282352478532746 bayes_pls_golite062009
DNA binding 0.259361683038035 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.220608508617331 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.219533217661421 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.219157471322311 bayes_pls_golite062009
protein transporter activity 0.178442534411253 bayes_pls_golite062009
DNA helicase activity 0.17029946873911 bayes_pls_golite062009
protein binding 0.071010918255742 bayes_pls_golite062009
minus-end-directed microtubule motor activity 0.068779631341469 bayes_pls_golite062009
transcription regulator activity 0.050107780790998 bayes_pls_golite062009
structure-specific DNA binding 0.0463883764000663 bayes_pls_golite062009
cation transmembrane transporter activity 0.0254369227200564 bayes_pls_golite062009
structural constituent of cytoskeleton 0.0111338193708552 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [370-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YQSLVSELRD EVSRLRTKML TERPRSGAAA AAAAAAASGS AGTAGSGAGS EAVQEQDEQR  60
   61 KTELRYLREQ IVLTFKQQMK LRRKLLEAES HLLGLELDAE RQHMIISHWQ GRIGKLYDAM 120
  121 GDDDIESEGS VALKNAWGEL AAIEKETRRY KEIRERTEHE LEQCRQKGVK LEDELPERIS 180
  181 SDEERELLAL LCRVHELEAD KVSLQAERLA RQAELRRRDL QLLRAERQRR LCEDIISSQR 240
  241 RLIEEGNVDL PDELRELYGL YQQEIHAGVV TPSTSNYERK LPPIYTAGSD SPGSSSSSEW 300
  301 SPASPLPQID NQMDPVDRVM GPPVNPRLPR LSAATSANVP AGGSRRPSLR VARNPHPHP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.045757
Match: 2i1jA
Description: No description for 2i1jA was found.

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Created and Maintained by: Michael Riffle