YRC Public Data Repository - Protein Structure Prediction

Protein:	ARP7
Organism:	Saccharomyces cerevisiae
Length:	477 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARP7.

Description	E-value	Query Range	Subject Range
ACTB_PONAB - Actin, cytoplasmic 1 OS=Pongo abelii GN=ACTB PE=2 SV=1 ACTB_CANLF - Actin, cytoplasmic 1 OS=Canis lupus familiaris GN=ACTB PE=2 SV=3 ACTB_BOVIN - Actin, cytoplasmic 1 OS=Bos taurus GN=ACTB PE=1 SV=1 gi\|54695168 - gi\|54695168\|dbj\|BAD67166.1\| beta-actin [Meriones unguiculatus] gi\|149409094 - gi\|149409094\|ref\|XP_001512727.1\| PREDICTED: similar to tripartite motif-containing 37 protein [Ornit... ACTB_PONPY - Actin, cytoplasmic 1 - Pongo pygmaeus (Orangutan) gi\|55250205, gi\|... - gb\|AAH86153.1\| Unknown (protein for MGC:98584) [Xenopus laevis], gb\|AAH86219.1\| Unknown (protein fo... gi\|60686894 - gi\|60686894\|gb\|AAX35537.1\| beta-actin [Meleagris gallopavo] ACTB_MOUSE - Actin, cytoplasmic 1 OS=Mus musculus GN=Actb PE=1 SV=1 ACTB_MESAU - Actin, cytoplasmic 1 OS=Mesocricetus auratus GN=ACTB PE=1 SV=1 gi\|123980114, gi... - gi\|60655869\|gb\|AAX32498.1\| actin beta [synthetic construct], gi\|168277960\|dbj\|BAG10958.1\| actin, cyt... ACTB_SPECI - Actin, cytoplasmic 1 OS=Spermophilus citellus GN=ACTB PE=2 SV=1 ACTB_MACFA - Actin, cytoplasmic 1 OS=Macaca fascicularis GN=ACTB PE=2 SV=1 gi\|74316002 - gi\|74316002\|ref\|NP_001028256.1\| beta-actin [Macaca mulatta] ACTB_SHEEP - Actin, cytoplasmic 1 OS=Ovis aries GN=ACTB PE=2 SV=1 ACTB_CHICK - Actin, cytoplasmic 1 OS=Gallus gallus GN=ACTB PE=1 SV=1 ACTB_CHLAE - Actin, cytoplasmic 1 OS=Chlorocebus aethiops GN=ACTB PE=2 SV=1 ACTB_RAT - Actin, cytoplasmic 1 OS=Rattus norvegicus GN=Actb PE=1 SV=1 ACTB_CAVPO - Actin, cytoplasmic 1 OS=Cavia porcellus GN=ACTB PE=2 SV=1 ENSCJAT00000000010 - null ACTB_HORSE - Actin, cytoplasmic 1 OS=Equus caballus GN=ACTB PE=2 SV=1 gi\|56342330\|dbj\|... - beta-actin [Pan troglodytes] tr\|G3GVD0\|G3GVD0... - Actin, cytoplasmic 1 OS=Cricetulus griseus GN=I79_001666 PE=3 SV=1 ACTB_TRIVU - Actin, cytoplasmic 1 OS=Trichosurus vulpecula GN=ACTB PE=2 SV=1 ACTB_PANTR - Actin, cytoplasmic 1 OS=Pan troglodytes GN=ACTB PE=2 SV=1 ACTB - actin, beta ACTB_PIG - Actin, cytoplasmic 1 OS=Sus scrofa GN=ACTB PE=1 SV=2 gi\|126338082, gi... - gi\|126338082\|ref\|XP_001362898.1\| PREDICTED: similar to beta actin isoform 1 [Monodelphis domestica],... gi\|542157396\|ref... - PREDICTED: actin, cytoplasmic 1 [Zonotrichia albicollis]	0.0	[1..469]	[1..374]
gi\|189099631 - gi\|189099631\|gb\|ACD76987.1\| beta actin [Leucoraja erinacea] ACTG_TRISC - Actin, cytoplasmic 2 OS=Triakis scyllium GN=actg1 PE=2 SV=1	0.0	[1..469]	[1..374]
ACTB_XENLA - Actin, cytoplasmic 1 OS=Xenopus laevis GN=actb PE=2 SV=1	0.0	[1..469]	[1..374]
gi\|7546744 - gi\|7546744\|gb\|AAF63665.1\| beta-actin [Platichthys flesus] gi\|33089964 - gi\|33089964\|gb\|AAP93862.1\| beta-actin [Perca flavescens] gi\|56554009 - gi\|56554009\|gb\|AAV97945.1\| beta actin 2 [Rivulus marmoratus]	0.0	[1..469]	[1..374]
gi\|194130965, gi... - gi\|195340496\|ref\|XP_002036849.1\| GM12447 [Drosophila sechellia], gi\|194130965\|gb\|EDW53008.1\| GM12447... gi\|195401955, gi... - gi\|195401955\|ref\|XP_002059576.1\| GJ14747 [Drosophila virilis], gi\|194147283\|gb\|EDW62998.1\| GJ14747 [... gi\|195432731, gi... - gi\|195432731\|ref\|XP_002064370.1\| GK20124 [Drosophila willistoni], gi\|194160455\|gb\|EDW75356.1\| GK2012... gi\|195480603, gi... - gi\|195480603\|ref\|XP_002101323.1\| Act57B [Drosophila yakuba], gi\|194188847\|gb\|EDX02431.1\| Act57B [Dro... gi\|89473786, gi\|... - gi\|89473786\|gb\|ABD72705.1\| putative actin [Acyrthosiphon pisum], gi\|187109134\|ref\|NP_001119672.1\| ac... gi\|195565315, gi... - gi\|195565315\|ref\|XP_002106247.1\| GD16764 [Drosophila simulans], gi\|194203621\|gb\|EDX17197.1\| GD16764 ... ACT4_BOMMO - Actin, cytoplasmic A4 OS=Bombyx mori GN=A4 PE=2 SV=1 gi\|91088365, gi\|... - gi\|91088369\|ref\|XP_976070.1\| PREDICTED: similar to Actin-5C isoform 3 [Tribolium castaneum], gi\|9108... gi\|220947776, gi... - gi\|220957086\|gb\|ACL91086.1\| Act5C-PA [synthetic construct], gi\|220947776\|gb\|ACL86431.1\| Act5C-PA [sy... gi\|170048737, gi... - gi\|170048737\|ref\|XP_001870756.1\| conserved hypothetical protein [Culex quinquefasciatus], gi\|1678707... gi\|190648678, gi... - gi\|194889160\|ref\|XP_001977029.1\| GG18797 [Drosophila erecta], gi\|190648678\|gb\|EDV45956.1\| GG18797 [D... gi\|193892986, gi... - gi\|195046398\|ref\|XP_001992145.1\| GH24372 [Drosophila grimshawi], gi\|193892986\|gb\|EDV91852.1\| GH24372... gi\|125981707\|ref... - GA17886-PA [Drosophila pseudoobscura], GA17886 [Drosophila pseudoobscura pseudoobscura] gi\|193907820, gi... - gi\|195129856\|ref\|XP_002009370.1\| GI15312 [Drosophila mojavensis], gi\|193907820\|gb\|EDW06687.1\| GI1531... gi\|195166956, gi... - gi\|195166956\|ref\|XP_002024300.1\| GL14888 [Drosophila persimilis], gi\|194107673\|gb\|EDW29716.1\| GL1488... FBpp0311818, Act... - The gene Actin 5C is referred to in FlyBase by the symbol Dmel\Act5C (CG4027, FBgn0000042). It is a ... ACT5C_ANOGA - Actin-5C OS=Anopheles gambiae GN=Act5C PE=2 SV=1 gi\|54643168, gi\|... - gi\|54643168\|gb\|EAL31912.1\| GA17886 [Drosophila pseudoobscura pseudoobscura], gi\|125981707\|ref\|XP_001... gi\|157128681, gi... - gi\|157128681\|ref\|XP_001655176.1\| actin [Aedes aegypti], gi\|157128679\|ref\|XP_001655175.1\| actin [Aede... gi\|52630919 - gi\|52630919\|gb\|AAU84923.1\| putative actin [Toxoptera citricida] ACT3B_HELAM - Actin-A3b, cytoplasmic OS=Helicoverpa armigera GN=actA3b PE=2 SV=1 gi\|118780938, gi... - gi\|58381342\|ref\|XP_311177.2\| ENSANGP00000019055 [Anopheles gambiae str. PEST], gi\|55242984\|gb\|EAA068...	0.0	[2..469]	[3..375]
gi\|63018 - gi\|63018\|emb\|CAA25004.1\| beta-actin [Gallus gallus]	0.0	[1..469]	[1..374]
ACTB_SIGHI - Actin, cytoplasmic 1 OS=Sigmodon hispidus GN=ACTB PE=2 SV=1	0.0	[1..469]	[1..374]
ACTB_CRIGR - Actin, cytoplasmic 1 OS=Cricetulus griseus GN=ACTB PE=3 SV=1	0.0	[1..469]	[1..374]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[2..469]	[1..373]

Back

Predicted Domain #1

Region A:
Residues: [1-141]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLNRKCVVI HNGSHRTVAG FSNVELPQCI IPSSYIKRTD EGGEAEFIFG TYNMIDAAAE  60
   61 KRNGDEVYTL VDSQGLPYNW DALEMQWRYL YDTQLKVSPE ELPLVITMPA TNGKPDMAIL 120
  121 ERYYELAFDK LNVPVFQIVI E

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [436-477]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GWLGALTMAN LPSWSLGKWY SKEDYETLKR DRKQSQATNA TN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1153.9794
Match:	1yagA_
Description:	Actin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
histone acetyltransferase activity	6.00435371802752	bayes_pls_golite062009
lysine N-acetyltransferase activity	6.00435371802752	bayes_pls_golite062009
N-acetyltransferase activity	4.4623239863508	bayes_pls_golite062009
N-acyltransferase activity	4.17753709537507	bayes_pls_golite062009
acetyltransferase activity	3.85999832240402	bayes_pls_golite062009
DNA helicase activity	3.48040623488385	bayes_pls_golite062009
acyltransferase activity	3.31611368687679	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.27955167799398	bayes_pls_golite062009
structural constituent of cytoskeleton	3.14961582364442	bayes_pls_golite062009
ATP-dependent 5'-3' DNA helicase activity	3.13915061980648	bayes_pls_golite062009
5'-3' DNA helicase activity	3.13915061980648	bayes_pls_golite062009
cytoskeletal protein binding	3.11425505645918	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.10494259200141	bayes_pls_golite062009
actin binding	2.955791490673	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	2.77568295763272	bayes_pls_golite062009
kinase activity	2.39470546929151	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	2.28750451001371	bayes_pls_golite062009
binding	2.11855816699924	bayes_pls_golite062009
transcription regulator activity	2.09111975841662	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.06985477154666	bayes_pls_golite062009
protein binding	2.00711904074672	bayes_pls_golite062009
nucleic acid binding	1.84294882554466	bayes_pls_golite062009
DNA binding	1.70014394990425	bayes_pls_golite062009
actin filament binding	1.46443668299938	bayes_pls_golite062009
myosin binding	1.42865156375885	bayes_pls_golite062009
transcription activator activity	1.35676801272576	bayes_pls_golite062009
transferase activity	1.25544026047211	bayes_pls_golite062009
structural molecule activity	1.15845050752717	bayes_pls_golite062009
transcription factor activity	1.06678984888387	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.881722720970167	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.879451540876829	bayes_pls_golite062009
DNA-dependent ATPase activity	0.866917783590327	bayes_pls_golite062009
pyrophosphatase activity	0.856477452112878	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.7632451328636	bayes_pls_golite062009
transporter activity	0.723965474347776	bayes_pls_golite062009
ATPase activity	0.659547529412626	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.574998559133169	bayes_pls_golite062009
protein kinase activity	0.344796257628435	bayes_pls_golite062009
nucleosome binding	0.329990231856661	bayes_pls_golite062009
catalytic activity	0.296484721581333	bayes_pls_golite062009
ATP-dependent DNA helicase activity	0.166787445046116	bayes_pls_golite062009
adenyl nucleotide binding	0.162883291947849	bayes_pls_golite062009
substrate-specific transporter activity	0.151784261278389	bayes_pls_golite062009
ATP binding	0.13613543261671	bayes_pls_golite062009
carbohydrate kinase activity	0.123282448317819	bayes_pls_golite062009
adenyl ribonucleotide binding	0.0977998908064818	bayes_pls_golite062009
chromatin binding	0.0489277194984092	bayes_pls_golite062009
unfolded protein binding	0.0304569608189402	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [142-435]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PLAIALSMGK SSAFVIDIGA SGCNVTPIID GIVVKNAVVR SKFGGDFLDF QVHERLAPLI  60
   61 KEENDMENMA DEQKRSTDVW YEASTWIQQF KSTMLQVSEK DLFELERYYK EQADIYAKQQ 120
  121 EQLKQMDQQL QYTALTGSPN NPLVQKKNFL FKPLNKTLTL DLKECYQFAE YLFKPQLISD 180
  181 KFSPEDGLGP LMAKSVKKAG ASINSMKANT STNPNGLGTS HINTNVGDNN STASSSNISP 240
  241 EQVYSLLLTN VIITGSTSLI EGMEQRIIKE LSIRFPQYKL TTFANQVMMD RKIQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1153.9794
Match:	1yagA_
Description:	Actin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: