| Protein: | RAS1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 309 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RAS1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..309] | [1..309] |
|
|
2.0E-91 | [1..211] | [1..213] |
|
|
4.0E-91 | [3..212] | [7..217] |
|
|
6.0E-91 | [3..212] | [6..217] |
|
|
1.0E-89 | [3..211] | [7..216] |
|
|
1.0E-89 | [4..211] | [2..201] |
|
Region A: Residues: [1-185] |
1 11 21 31 41 51
| | | | | |
1 MQGNKSTIRE YKIVVVGGGG VGKSALTIQF IQSYFVDEYD PTIEDSYRKQ VVIDDKVSIL 60
61 DILDTAGQEE YSAMREQYMR TGEGFLLVYS VTSRNSFDEL LSYYQQIQRV KDSDYIPVVV 120
121 VGNKLDLENE RQVSYEDGLR LAKQLNAPFL ETSAKQAINV DEAFYSLIRL VRDDGGKYNS 180
181 MNRQL
|
| Detection Method: |  |
| Confidence: | 594.68867 |
| Match: | 821p__ |
| Description: | cH-p21 Ras protein |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| structural constituent of ribosome | 4.14187056198902 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 3.57926427233638 | bayes_pls_golite062009 |
| structural molecule activity | 3.22453402481353 | bayes_pls_golite062009 |
| transporter activity | 3.10463051760206 | bayes_pls_golite062009 |
| transmembrane transporter activity | 2.95886887664984 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 2.95079405147356 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.87427509025394 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 2.85499564954033 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 2.85178667290149 | bayes_pls_golite062009 |
| motor activity | 2.79327761685782 | bayes_pls_golite062009 |
| microtubule motor activity | 2.74365461017633 | bayes_pls_golite062009 |
| organic acid transmembrane transporter activity | 2.67957846350199 | bayes_pls_golite062009 |
| carboxylic acid transmembrane transporter activity | 2.67815672695824 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 2.61775212528604 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 2.61467977505707 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 2.61311581579476 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 2.57552435627908 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 2.57107347424517 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 2.57054427875021 | bayes_pls_golite062009 |
| hydrolase activity | 2.55157966585974 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 2.50934147358924 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 2.50494515048649 | bayes_pls_golite062009 |
| ATPase activity, coupled | 2.43862163407966 | bayes_pls_golite062009 |
| ATPase activity | 2.39535714892224 | bayes_pls_golite062009 |
| G-protein coupled receptor activity | 2.3505608190884 | bayes_pls_golite062009 |
| amine transmembrane transporter activity | 2.29486577878686 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| RNA helicase activity | 2.05761688027604 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 1.91091452720653 | bayes_pls_golite062009 |
| guanyl nucleotide binding | 1.89320355239381 | bayes_pls_golite062009 |
| guanyl ribonucleotide binding | 1.88721318481223 | bayes_pls_golite062009 |
| GTP binding | 1.87900088157196 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.85943679361938 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.85937484083653 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.8521191028835 | bayes_pls_golite062009 |
| nucleotide binding | 1.84603132945448 | bayes_pls_golite062009 |
| kinase activity | 1.80889641165674 | bayes_pls_golite062009 |
| protein transporter activity | 1.71214667007262 | bayes_pls_golite062009 |
| GTPase activity | 1.6309422514633 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.60386625568858 | bayes_pls_golite062009 |
| amino acid transmembrane transporter activity | 1.59627719545436 | bayes_pls_golite062009 |
| ATP binding | 1.5859264197035 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.56325751172863 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.55520429131224 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.53158018507951 | bayes_pls_golite062009 |
| signal recognition particle binding | 1.46975774710831 | bayes_pls_golite062009 |
| actin binding | 1.42666717383185 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.40488517180956 | bayes_pls_golite062009 |
| microfilament motor activity | 1.33993901826495 | bayes_pls_golite062009 |
| transmembrane receptor activity | 1.26314334516725 | bayes_pls_golite062009 |
| protein binding | 1.22129154759482 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 1.2155186842031 | bayes_pls_golite062009 |
| receptor activity | 1.20313362488821 | bayes_pls_golite062009 |
| helicase activity | 1.16085745407703 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.14475274823167 | bayes_pls_golite062009 |
| signal transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| molecular transducer activity | 1.13474466330485 | bayes_pls_golite062009 |
| protein kinase activity | 1.12864835254143 | bayes_pls_golite062009 |
| apolipoprotein receptor activity | 1.02132483910092 | bayes_pls_golite062009 |
| syntaxin-13 binding | 1.02132483910092 | bayes_pls_golite062009 |
| apolipoprotein A-I binding | 1.02132483910092 | bayes_pls_golite062009 |
| apolipoprotein A-I receptor activity | 1.02132483910092 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| tubulin binding | 0.979946830272106 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.977237423302079 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 0.95986988363392 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 0.94128341275411 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| microtubule binding | 0.907162506177187 | bayes_pls_golite062009 |
| transcription activator activity | 0.889929694023098 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| protein methyltransferase activity | 0.876296121718575 | bayes_pls_golite062009 |
| transferase activity | 0.871779313294914 | bayes_pls_golite062009 |
| DNA helicase activity | 0.72881469450553 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 0.650964453464311 | bayes_pls_golite062009 |
| histone methyltransferase activity | 0.63002958837536 | bayes_pls_golite062009 |
| cell surface binding | 0.618263399939881 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 0.59513742813869 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.557919489256916 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.543891899378373 | bayes_pls_golite062009 |
| DNA clamp loader activity | 0.543512707823441 | bayes_pls_golite062009 |
| ribonucleoprotein binding | 0.53788302029845 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 0.46552249844591 | bayes_pls_golite062009 |
| branched-chain aliphatic amino acid transmembrane transporter activity | 0.442220326523999 | bayes_pls_golite062009 |
| actin filament binding | 0.437646833557392 | bayes_pls_golite062009 |
| signal sequence binding | 0.42240724331108 | bayes_pls_golite062009 |
| drug transmembrane transporter activity | 0.38711726712063 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.345873656782869 | bayes_pls_golite062009 |
| peptide binding | 0.304703625340488 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.249173645231486 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.22150712609541 | bayes_pls_golite062009 |
| amino acid-transporting ATPase activity | 0.147644650870465 | bayes_pls_golite062009 |
| amine-transporting ATPase activity | 0.135455889967401 | bayes_pls_golite062009 |
| nucleobase, nucleoside, nucleotide kinase activity | 0.12351419478929 | bayes_pls_golite062009 |
| inorganic cation transmembrane transporter activity | 0.123304946374679 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.0781650226500197 | bayes_pls_golite062009 |
| metal ion transmembrane transporter activity | 0.0775601177068852 | bayes_pls_golite062009 |
| RNA binding | 0.0693163519626152 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven protein transmembrane transporter activity | 0.00571427458217011 | bayes_pls_golite062009 |
| macromolecule transmembrane transporter activity | 0.00571427458217011 | bayes_pls_golite062009 |
|
Region A: Residues: [186-244] |
1 11 21 31 41 51
| | | | | |
1 DNTNEIRDSE LTSSATADRE KKNNGSYVLD NSLTNAGTGS SSKSAVNHNG ETTKRTDEK
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.352 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.521 | a.156.1 | S13-like H2TH domain |
| View | Download | 0.419 | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.372 | g.44.1 | RING/U-box |
| View | Download | 0.365 | d.17.3 | Disulfide bond isomerase, DsbC, N-terminal domain |
| View | Download | 0.350 | d.9.2 | Description not found. |
| View | Download | 0.346 | a.144.1 | PABC (PABP) domain |
| View | Download | 0.338 | b.38.1 | Sm-like ribonucleoproteins |
| View | Download | 0.325 | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.309 | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.296 | d.58.5 | GlnB-like |
| View | Download | 0.280 | d.42.1 | POZ domain |
| View | Download | 0.256 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.253 | d.58.17 | Metal-binding domain |
| View | Download | 0.244 | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.234 | g.3.11 | EGF/Laminin |
| View | Download | 0.228 | g.3.11 | EGF/Laminin |
| View | Download | 0.219 | a.4.2 | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| View | Download | 0.215 | d.58.17 | Metal-binding domain |
| View | Download | 0.205 | b.84.2 | Rudiment single hybrid motif |
|
Region A: Residues: [245-309] |
1 11 21 31 41 51
| | | | | |
1 NYVNQNNNNE GNTKYSSNGN GNRSDISRGN QNNALNSRSK QSAEPQKNSS ANARKESSGG 60
61 CCIIC
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.521 | 0.119 | activation of adenylate cyclase activity by G-protein signaling pathway | a.156.1 | S13-like H2TH domain |
| View | Download | 0.280 | 0.112 | activation of adenylate cyclase activity by G-protein signaling pathway | d.42.1 | POZ domain |
| View | Download | 0.346 | 0.050 | activation of adenylate cyclase activity by G-protein signaling pathway | a.144.1 | PABC (PABP) domain |
| View | Download | 0.219 | 0.019 | activation of adenylate cyclase activity by G-protein signaling pathway | a.4.2 | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
