| Protein: | PEP5 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 1029 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PEP5.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..1029] | [1..1030] |
|
|
0.0 | [5..1023] | [6..908] |
|
|
0.0 | [5..1023] | [6..908] |
|
|
0.0 | [5..1027] | [4..1015] |
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|
0.0 | [5..1027] | [4..993] |
|
|
0.0 | [3..1023] | [1..925] |
|
Region A: Residues: [1-377] |
1 11 21 31 41 51
| | | | | |
1 MSLSSWRQFQ LFENIPIRDP NFGGDSLLYS DPTLCAATIV DPQTLIIAVN SNIIKVVKLN 60
61 QSQVIHEFQS FPHDFQITFL KVINGEFLVA LAESIGKPSL IRVYKLEKLP NREQLYHSQV 120
121 ELKNGNNTYP ISVVSISNDL SCIVVGFING KIILIRGDIS RDRGSQQRII YEDPSKEPIT 180
181 ALFLNNDATA CFAATTSRIL LFNTTGRNRG RPSLVLNSKN GLDLNCGSFN PATNEFICCL 240
241 SNFIEFFSSS GKKHQFAFDL SLRKRIFCVD KDHILIVTEE TGVPTTSISV NELSPTIINR 300
301 IFIIDAKNKI ISLNFVVSSA IIDIFSTSQS GKNITYLLTS EGVMHRITPK SLENQINIII 360
361 QKELYPFALQ LAKQHSL
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 3.27972671455235 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 3.00024678477589 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 2.09205299847945 | bayes_pls_golite062009 |
| binding | 1.75605065075676 | bayes_pls_golite062009 |
| transporter activity | 1.23232041140488 | bayes_pls_golite062009 |
| protein binding | 1.04520986427713 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.750051725890322 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.450377149626952 | bayes_pls_golite062009 |
| kinase activity | 0.41337453952205 | bayes_pls_golite062009 |
| hydrolase activity | 0.346903609858078 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.271959658140432 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.260136536525518 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 0.190416660410399 | bayes_pls_golite062009 |
| nucleic acid binding | 0.103339839445939 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0245411309982146 | bayes_pls_golite062009 |
|
Region A: Residues: [378-635] |
1 11 21 31 41 51
| | | | | |
1 SPLDVQEIHK KYGDYLFKKG LRKEATDQYI QCLDVVETSE IISKFGVKEV PDPESMRNLA 60
61 DYLWSLIKNS ISQRDHVTLL LIVLIKLKDV EGIDTFIQHF DRKGIWNEGV VMDDMDDVTF 120
121 FYSDNDFFDL DLILELMKES DFKRLSYRLA KKYSKDSLII VDILLNLLHN PVKAIKYIKS 180
181 LPIDETLRCL VTYSKKLLEE SPNETNALLI EVFTGKFKPS TFEVDLDRRD TTGDFSENIR 240
241 TVFYSYKTFF NYMNSNGT
|
| Detection Method: | |
| Confidence: | 21.136677 |
| Match: | PF00637 |
| Description: | Region in Clathrin and VPS |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| protein transporter activity | 2.99345877012947 | bayes_pls_golite062009 |
| transporter activity | 2.3766833486706 | bayes_pls_golite062009 |
| binding | 2.33303322187387 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 2.12926593993985 | bayes_pls_golite062009 |
| protein binding | 1.5114863464349 | bayes_pls_golite062009 |
| transmembrane transporter activity | 1.2724388835449 | bayes_pls_golite062009 |
| protein transmembrane transporter activity | 1.12112006227201 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 1.04982314606251 | bayes_pls_golite062009 |
| hydrolase activity | 0.566325388018401 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 0.535131417738445 | bayes_pls_golite062009 |
| kinase activity | 0.507502362811171 | bayes_pls_golite062009 |
| nucleic acid binding | 0.497783403092344 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.416234300339629 | bayes_pls_golite062009 |
| signal sequence binding | 0.279693431859311 | bayes_pls_golite062009 |
| active transmembrane transporter activity | 0.260663498540354 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.256036243669218 | bayes_pls_golite062009 |
| transferase activity | 0.249515205994519 | bayes_pls_golite062009 |
| primary active transmembrane transporter activity | 0.234271600707329 | bayes_pls_golite062009 |
| P-P-bond-hydrolysis-driven transmembrane transporter activity | 0.225395946682209 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances | 0.186601655036333 | bayes_pls_golite062009 |
| ATPase activity, coupled to movement of substances | 0.183072614802483 | bayes_pls_golite062009 |
| ATPase activity, coupled to transmembrane movement of substances | 0.182751938544977 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.109435859778099 | bayes_pls_golite062009 |
| clathrin binding | 0.0923079381755934 | bayes_pls_golite062009 |
| pyrophosphatase activity | 0.0728493557966827 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.0641324729536009 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.0615190129942244 | bayes_pls_golite062009 |
| cation transmembrane transporter activity | 0.0475280280823402 | bayes_pls_golite062009 |
| protein kinase activity | 0.0308998889737299 | bayes_pls_golite062009 |
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Region A: Residues: [636-865] |
1 11 21 31 41 51
| | | | | |
1 SDAMSESSEA SHEHEEPTYH PPKPSIVFSS FVTKPFEFVV FLEACLACYQ QYEGFDEDRQ 60
61 VILTTLYDLY LNLAQNDVPE RIDDWRSRAT GVLRESNKLV YSAASNNTSK RVDNSIMLLI 120
121 SHMDQSSASA KDKTKIDIAS FANDNPEMDL LSTFRAMTLN EEPSTCLKFL EKYGTEEPKL 180
181 LQVALSYFVS NKLIFKEMGG NEVLKEKVLR PIIEGERMPL LDIIKALSRT
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.97121728620188 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.78935175140238 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.75377804653841 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 2.57382484274962 | bayes_pls_golite062009 |
| binding | 2.15929427993458 | bayes_pls_golite062009 |
| protein binding | 1.49775478023418 | bayes_pls_golite062009 |
| SUMO polymer binding | 0.805553743681771 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 0.786612602432575 | bayes_pls_golite062009 |
| ligase activity | 0.63517530468004 | bayes_pls_golite062009 |
| hydrolase activity | 0.626901453756812 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 0.549461161056205 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.159023519781458 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| nucleic acid binding | 0.125491277540945 | bayes_pls_golite062009 |
| transcription regulator activity | 0.0833655277418337 | bayes_pls_golite062009 |
|
Region A: Residues: [866-1029] |
1 11 21 31 41 51
| | | | | |
1 NVAHFGLIQD IIIDHVKTED TEIKRNEKLI ESYDKELKEK NKKLKNTINS DQPLHVPLKN 60
61 QTCFMCRLTL DIPVVFFKCG HIYHQHCLNE EEDTLESERK LFKCPKCLVD LETSNKLFEA 120
121 QHEVVEKNDL LNFALNSEEG SRDRFKVITE FLGRGAISYS DITI
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| Detection Method: | |
| Confidence: | 2.69897 |
| Match: | 1jm7B_ |
| Description: | bard1 RING domain |
Matching Structure (courtesy of the PDB): |
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