| Protein: | ITT1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 464 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ITT1.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-98 | [1..464] | [1..464] |
|
|
2.0E-63 | [7..459] | [10..462] |
|
|
1.0E-62 | [7..459] | [10..461] |
|
|
5.0E-60 | [8..460] | [16..425] |
|
|
1.0E-57 | [41..453] | [3..329] |
|
Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MALTQFENDL EILRDMYPEL EMKSVKVEEE GEFPQRINGK LLFKISLLAD VNIEFGEQHM 60
61 LLSNLSNECV EFTIYSC
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.729 | 0.057 | regulation of translational termination | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.772 | 0.040 | regulation of translational termination | a.8.3 | Families 57/38 glycoside transferase middle domain |
| View | Download | 0.753 | 0.039 | regulation of translational termination | a.24.4 | Hemerythrin |
| View | Download | 0.581 | 0.008 | regulation of translational termination | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.617 | N/A | N/A | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.563 | N/A | N/A | a.28.1 | ACP-like |
| View | Download | 0.552 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.544 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.462 | N/A | N/A | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.421 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.412 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.385 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.372 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.359 | N/A | N/A | a.153.1 | Nuclear receptor coactivator interlocking domain |
| View | Download | 0.337 | N/A | N/A | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.335 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.333 | N/A | N/A | a.8.2 | Plasmid maintenance system epsilon/zeta, antidote epsilon subunit |
| View | Download | 0.327 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.325 | N/A | N/A | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.324 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.318 | N/A | N/A | a.7.7 | BAG domain |
| View | Download | 0.316 | N/A | N/A | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.309 | N/A | N/A | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.303 | N/A | N/A | a.126.1 | Serum albumin-like |
| View | Download | 0.302 | N/A | N/A | d.50.3 | PI-Pfui intein middle domain |
| View | Download | 0.297 | N/A | N/A | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.296 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.295 | N/A | N/A | a.5.6 | Hypothetical protein MTH1615 |
| View | Download | 0.282 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.279 | N/A | N/A | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.277 | N/A | N/A | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.275 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.273 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.270 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.268 | N/A | N/A | a.60.6 | DNA polymerase beta, N-terminal domain-like |
| View | Download | 0.262 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.261 | N/A | N/A | a.64.2 | Bacteriocin AS-48 |
| View | Download | 0.250 | N/A | N/A | a.2.7 | tRNA-binding arm |
| View | Download | 0.247 | N/A | N/A | a.130.1 | Chorismate mutase II |
| View | Download | 0.245 | N/A | N/A | a.39.1 | EF-hand |
| View | Download | 0.245 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.243 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.241 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.240 | N/A | N/A | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.239 | N/A | N/A | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.233 | N/A | N/A | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.232 | N/A | N/A | i.1.1 | Ribosome and ribosomal fragments |
| View | Download | 0.230 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.227 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.223 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.222 | N/A | N/A | a.7.5 | Tubulin chaperone cofactor A |
| View | Download | 0.217 | N/A | N/A | a.135.1 | Tetraspanin |
| View | Download | 0.203 | N/A | N/A | a.7.2 | Enzyme IIa from lactose specific PTS, IIa-lac |
| View | Download | 0.202 | N/A | N/A | a.47.2 | t-snare proteins |
|
Region A: Residues: [78-153] |
1 11 21 31 41 51
| | | | | |
1 HYPDIRRCVV MDIKSLWIST DEKKMLIDKA LRLVEETVDM SIEFADSFTS ILILIFGFLI 60
61 DDTAILLFPN GIRKCL
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [154-251] |
1 11 21 31 41 51
| | | | | |
1 TQDQYDLFKQ ISEEATLQKV SRSNYHCCIC MEMEKGVRMI KLPCENANVE HYLCRGCAKS 60
61 YFTAMIQENR ISSVRCPQCE YKELKLEDFK SYKKMLKA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.656 | 0.175 | regulation of translational termination | a.77.1 | DEATH domain |
| View | Download | 0.541 | 0.135 | regulation of translational termination | a.118.8 | TPR-like |
| View | Download | 0.575 | 0.092 | regulation of translational termination | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.520 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.469 | N/A | N/A | c.53.1 | Resolvase-like |
| View | Download | 0.452 | N/A | N/A | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.443 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.419 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.419 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.395 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.390 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.376 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.371 | N/A | N/A | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.368 | N/A | N/A | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.368 | N/A | N/A | a.3.1 | Cytochrome c |
| View | Download | 0.363 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.363 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.362 | N/A | N/A | a.40.1 | Calponin-homology domain, CH-domain |
| View | Download | 0.347 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.347 | N/A | N/A | c.10.1 | RNI-like |
| View | Download | 0.314 | N/A | N/A | d.237.1 | Hypothetical protein YjiA, C-terminal domain |
| View | Download | 0.312 | N/A | N/A | d.68.3 | SirA-like |
| View | Download | 0.312 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.310 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.302 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.299 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.298 | N/A | N/A | d.52.4 | YhbC-like, N-terminal domain |
| View | Download | 0.298 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.296 | N/A | N/A | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.295 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.294 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.292 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.291 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.289 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.288 | N/A | N/A | d.68.3 | SirA-like |
| View | Download | 0.278 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.277 | N/A | N/A | d.68.3 | SirA-like |
| View | Download | 0.272 | N/A | N/A | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.271 | N/A | N/A | c.55.5 | MTH1175-like |
| View | Download | 0.269 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.264 | N/A | N/A | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.257 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.254 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.250 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.248 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.246 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.238 | N/A | N/A | d.79.3 | L30e-like |
| View | Download | 0.237 | N/A | N/A | c.32.1 | Tubulin/Dihydroxyacetone kinase nucleotide-binding domain |
| View | Download | 0.230 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.228 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.225 | N/A | N/A | a.11.1 | Acyl-CoA binding protein |
| View | Download | 0.225 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.223 | N/A | N/A | a.92.1 | Carbamoyl phosphate synthetase, large subunit connection domain |
| View | Download | 0.220 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.215 | N/A | N/A | c.2.1 | NAD(P)-binding Rossmann-fold domains |
| View | Download | 0.213 | N/A | N/A | d.169.1 | C-type lectin-like |
| View | Download | 0.211 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.205 | N/A | N/A | c.58.1 | Aminoacid dehydrogenase-like, N-terminal domain |
| View | Download | 0.203 | N/A | N/A | a.64.1 | Saposin |
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [252-338] |
1 11 21 31 41 51
| | | | | |
1 LFTPLIPVSF LKEVIDTELC ERYEKMFYNQ AATRLSKYCP YACVTCRRCD SWCTKEDLDD 60
61 AMIQCQKCHF VFCFDCLHAW HGYNNKC
|
| Detection Method: | |
| Confidence: | 18.920819 |
| Match: | PF01485 |
| Description: | IBR domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [339-464] |
1 11 21 31 41 51
| | | | | |
1 GKKVSLSTDI IEEYLDDTVT SYERKRKLEA KYGRRVLELE VNDYLAEKML DLAIKKEGSN 60
61 LQRCPKCKVV VERSEGCNKM KCEVCGTLFC FICGVLLYPE DPYEHFREAY SGCYGRLFEG 120
121 MPGTET
|
| Detection Method: | |
| Confidence: | 2.075721 |
| Match: | PF01485 |
| Description: | IBR domain |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
