| Protein: | HSE1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 452 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HSE1.
| Description | E-value | Query Range |
Subject Range |
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9.0E-89 | [1..452] | [1..452] |
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1.0E-72 | [4..440] | [5..460] |
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3.0E-70 | [4..440] | [5..460] |
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2.0E-69 | [4..439] | [5..457] |
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3.0E-64 | [2..420] | [3..424] |
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4.0E-56 | [5..374] | [6..367] |
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2.0E-51 | [5..440] | [7..499] |
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Region A: Residues: [1-78] |
1 11 21 31 41 51
| | | | | |
1 MSSSAIKIRN ALLKATDPKL RSDNWQYILD VCDLVKEDPE DNGQEVMSLI EKRLEQQDAN 60
61 VILRTLSLTV SLAENCGS
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| Detection Method: |  |
| Confidence: | 132.594777 |
| Match: | 1elkA_ |
| Description: | Tom1 protein |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [79-146] |
1 11 21 31 41 51
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1 RLRQEISSKN FTSLLYALIE SHSVHITLKK AVTDVVKQLS DSFKDDPSLR AMGDLYDKIK 60
61 RKAPYLVQ
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| Detection Method: | |
| Confidence: | 132.594777 |
| Match: | 1elkA_ |
| Description: | Tom1 protein |
| Matching Structure (courtesy of the PDB): |
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Region A: Residues: [147-207] |
1 11 21 31 41 51
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1 PNVPEKHNMS TQADNSDDEE LQKALKMSLF EYEKQKKLQE QEKESAEVLP QQQQQHQQQN 60
61 Q
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.608 | a.4.1 | Homeodomain-like |
| View | Download | 0.724 | a.108.1 | Ribosomal protein L7/12, oligomerisation (N-terminal) domain |
| View | Download | 0.600 | a.30.1 | ROP protein |
| View | Download | 0.739 | a.164.1 | C-terminal domain of DFF45/ICAD (DFF-C domain) |
| View | Download | 0.659 | a.2.2 | Ribosomal protein L29 (L29p) |
| View | Download | 0.551 | a.2.3 | Chaperone J-domain |
| View | Download | 0.536 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.524 | a.2.9 | C-terminal UvrC-binding domain of UvrB |
| View | Download | 0.510 | a.64.1 | Saposin |
| View | Download | 0.480 | a.30.2 | Homodimeric domain of signal transducing histidine kinase |
| View | Download | 0.480 | a.3.1 | Cytochrome c |
| View | Download | 0.466 | a.2.7 | tRNA-binding arm |
| View | Download | 0.455 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.450 | a.64.1 | Saposin |
| View | Download | 0.443 | a.17.1 | p8-MTCP1 |
| View | Download | 0.433 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.432 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.413 | a.46.1 | Methionine synthase domain |
| View | Download | 0.404 | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.389 | a.4.13 | Sigma3 and sigma4 domains of RNA polymerase sigma factors |
| View | Download | 0.386 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.375 | a.37.1 | A DNA-binding domain in eukaryotic transcription factors |
| View | Download | 0.372 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.362 | a.2.8 | Eukaryotic DNA topoisomerase I, dispensable insert domain |
| View | Download | 0.357 | a.23.5 | Hemolysin expression modulating protein HHA |
| View | Download | 0.356 | a.4.8 | Ribosomal protein S18 |
| View | Download | 0.355 | a.47.2 | t-snare proteins |
| View | Download | 0.340 | a.64.1 | Saposin |
| View | Download | 0.339 | a.7.7 | BAG domain |
| View | Download | 0.304 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.293 | a.2.10 | Epsilon subunit of F1F0-ATP synthase C-terminal domain |
| View | Download | 0.291 | a.16.1 | S15/NS1 RNA-binding domain |
| View | Download | 0.285 | g.57.1 | Serine proteinase inhibitor lekti |
| View | Download | 0.280 | a.32.1 | Transcription factor IIA (TFIIA), alpha-helical domain |
| View | Download | 0.272 | a.3.1 | Cytochrome c |
| View | Download | 0.271 | a.4.1 | Homeodomain-like |
| View | Download | 0.257 | a.3.1 | Cytochrome c |
| View | Download | 0.252 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.242 | a.64.1 | Saposin |
| View | Download | 0.237 | a.2.6 | Effector domain of the protein kinase pkn/prk1 |
| View | Download | 0.230 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.228 | a.60.2 | RuvA domain 2-like |
| View | Download | 0.221 | a.13.1 | alpha-2-Macroglobulin receptor associated protein (RAP) domain 1 |
| View | Download | 0.220 | a.140.2 | SAP domain |
| View | Download | 0.208 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.201 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.200 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| Term | Confidence | Notes |
| binding | 2.47621789723131 | bayes_pls_golite062009 |
| protein binding | 2.10925438883926 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.29637592432055 | bayes_pls_golite062009 |
| ubiquitin-protein ligase activity | 1.02097165614658 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.938262449967509 | bayes_pls_golite062009 |
| transporter activity | 0.781252315942763 | bayes_pls_golite062009 |
| hydrolase activity | 0.539213162060111 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.523669943250984 | bayes_pls_golite062009 |
| actin binding | 0.4786890657602 | bayes_pls_golite062009 |
| nucleic acid binding | 0.476094076158571 | bayes_pls_golite062009 |
| structural molecule activity | 0.236653863910566 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.207376833349132 | bayes_pls_golite062009 |
| transcription regulator activity | 0.151103447043301 | bayes_pls_golite062009 |
| DNA binding | 0.143439914163001 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 0.125965304296204 | bayes_pls_golite062009 |
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Region A: Residues: [208-303] |
1 11 21 31 41 51
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1 APAHKIPAQT VVRRVRALYD LTTNEPDELS FRKGDVITVL EQVYRDWWKG ALRGNMGIFP 60
61 LNYVTPIVEP SKEEIEKEKN KEAIVFSQKT TIDQLH
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| Detection Method: | |
| Confidence: | 137.94696 |
| Match: | 1griA_ |
| Description: | Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2) |
Matching Structure (courtesy of the PDB): |
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Region A: Residues: [304-452] |
1 11 21 31 41 51
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1 NSLNAASKTG NSNEVLQDPH IGDMYGSVTP LRPQVTRMLG KYAKEKEDML SLRQVLANAE 60
61 RSYNQLMDRA ANAHISPPVP GPALYAGMTH ANNTPVMPPQ RQSYQSNEYS PYPSNLPIQH 120
121 PTNSANNTPQ YGYDLGYSVV SQPPPGYEQ
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| Detection Method: | |
| Confidence: | 137.94696 |
| Match: | 1griA_ |
| Description: | Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains; Growth factor receptor-bound protein 2 (GRB2) |
| Matching Structure (courtesy of the PDB): |
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