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View Structure Prediction Details

Protein: ELP2
Organism: Saccharomyces cerevisiae
Length: 788 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ELP2.

Description E-value Query
Range
Subject
Range
YY46_NOSS1 - Uncharacterized WD repeat-containing protein alr3466 OS=Nostoc sp. (strain PCC 7120 / UTEX 2576) GN=...
gi|25530855 - pir||AC2239 WD-40 repeat protein [imported] - Nostoc sp. (strain PCC 7120)
0.0 [60..744] [865..1491]
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain ATCC 27184 / PCC 6...
Y163_SYNY3 - Uncharacterized WD repeat-containing protein sll0163 OS=Synechocystis sp. (strain PCC 6803 / Kazusa)...
gi|7446132 - pir||S76086 beta transducin-like protein, 190K - Synechocystis sp. (strain PCC 6803)
0.0 [5..705] [1045..1683]

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Predicted Domain #1
Region A:
Residues: [1-542]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVECITPEAI FIGANKQTQV SDIHKVKKIV AFGAGKTIAL WDPIEPNNKG VYATLKGHEA  60
   61 EVTCVRFVPD SDFMVSASED HHVKIWKFTD YSHLQCIQTI QHYSKTIVAL SALPSLISVG 120
  121 CADGTISIWR QNIQNDEFGL AHEFTIKKGF FYPLCLSLSK VEEKKYLLAI GGTNVNVFIA 180
  181 SFILSDSGIE KCRVVAELEG HEDWVKSLAF RHQETPGDYL LCSGSQDRYI RLWRIRINDL 240
  241 IDDSEEDSKK LTLLSNKQYK FQIDDELRVG INFEALIMGH DDWISSLQWH ESRLQLLAAT 300
  301 ADTSLMVWEP DETSGIWVCS LRLGEMSSKG ASTATGSSGG FWSCLWFTHE RMDFFLTNGK 360
  361 TGSWRMWATK DNIICDQRLG ISGATKDVTD IAWSPSGEYL LATSLDQTTR LFAPWIYDAS 420
  421 GRKREIATWH EFSRPQIHGY DMICVETVTD TRFVSGGDEK ILRSFDLPKG VAGMLQKFVG 480
  481 IQFEEKSEMP DSATVPVLGL SNKAGEDDAN EDDEEEEGGN KETPDITDPL SLLECPPMED 540
  541 QL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1k32A_
Description: Tricorn protease; Tricorn protease N-terminal domain; Tricorn protease domain 2
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [543-634]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QRHLLWPEVE KLYGHGFEIT CLDISPDQKL IASACRSNNV QNAVIRIFST ENWLEIKPAL  60
   61 PFHSLTITRL KFSKDGKFLL SVCRDRKWAL WE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 90.927757
Match: 1gg2B_
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
actin binding 3.31804728298431 bayes_pls_golite062009
small conjugating protein ligase activity 3.13054264433898 bayes_pls_golite062009
cytoskeletal protein binding 3.1056443224755 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.00646122159505 bayes_pls_golite062009
tubulin binding 2.76945430061825 bayes_pls_golite062009
microtubule binding 2.72684103222924 bayes_pls_golite062009
dynein binding 2.54821997913979 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
2.40807791198019 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
acid-amino acid ligase activity 2.17819869145391 bayes_pls_golite062009
dynactin binding 1.85146647785657 bayes_pls_golite062009
snoRNA binding 1.76991421703041 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
actin filament binding 1.5197243426595 bayes_pls_golite062009
RNA binding 1.50295916950465 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.4866444894826 bayes_pls_golite062009
hydrolase activity 1.36960741137363 bayes_pls_golite062009
protein binding 1.21879977456466 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.21305848427711 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
microtubule plus-end binding 1.01166033978052 bayes_pls_golite062009
ligase activity 0.93058496790047 bayes_pls_golite062009
transporter activity 0.692270256454453 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.676924760416604 bayes_pls_golite062009
transcription repressor activity 0.658573452658359 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
dynein intermediate chain binding 0.443846546939402 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.426429095658617 bayes_pls_golite062009
kinase activity 0.387572734234845 bayes_pls_golite062009
molecular transducer activity 0.367729389382533 bayes_pls_golite062009
signal transducer activity 0.367729389382533 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
structural molecule activity 0.254012051644049 bayes_pls_golite062009
protein kinase activity 0.229242350006544 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.226335610368636 bayes_pls_golite062009
transcription corepressor activity 0.182612389752591 bayes_pls_golite062009
histone binding 0.166694897714113 bayes_pls_golite062009
chromatin binding 0.151977098745772 bayes_pls_golite062009
substrate-specific transporter activity 0.121183207943714 bayes_pls_golite062009
structural constituent of cytoskeleton 0.118975415284669 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.00585398682921312 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [635-711]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RNMEDNTFEL RFKNEKPHTR IIWDADWAPL EFGNVFVTAS RDKTVKVWRH QKEPADDYVL  60
   61 EASIKHTKAV TAISIHD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 136.9897
Match: 1erjA_
Description: Tup1, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [712-788]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SMIREKILIS VGLENGEIYL YSYTLGKFEL ITQLNEDITP ADKITRLRWS HLKRNGKLFL  60
   61 GVGSSDLSTR IYSLAYE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.897 0.479 regulation of transcription from RNA polymerase II promoter b.1.1 Immunoglobulin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle