| Protein: | CDC13 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 924 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC13.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..924] | [1..924] |
|
Region A: Residues: [1-490] |
1 11 21 31 41 51
| | | | | |
1 MDTLEEPECP PHKNRIFVSS SKDFEGYPSK AIVPVQFVAL LTSIHLTETK CLLGFSNFER 60
61 RGDQSQEDQY LIKLKFKDRG SERLARITIS LLCQYFDIEL PDLDSDSGAS PTVILRDIHL 120
121 ERLCFSSCKA LYVSKHGNYT LFLEDIKPLD LVSVISTIST KSTNSSKHSS SELISECDLN 180
181 NSLVDIFNNL IEMNRDEKNR FKFVKLIHYD IELKKFVQDQ QKVLSQKSKA AAINPFFVPN 240
241 RLGIPYIESQ NEFNSQLMTL NVDEPTTDIS NMGEEMHDSA DPIEDSDSST TSSTGKYFSS 300
301 KSYIQSQTPE RKTSVPNNWH DDDSGSKRKR KLSFHSPNAS SIRKAISYEQ LSLASVGSVE 360
361 RLEGKIVGMN PPQFASINEF KYCTLKLYFT QLLPNVPDKV LVPGVNCIEI VIPTRERICE 420
421 LFGVLNCQSD KISDILLLEK PDRISVEVER ILWDNDKTAS PGMAVWSLKN ISTDTQAQAQ 480
481 VQVPAQSSAS
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [491-641] |
1 11 21 31 41 51
| | | | | |
1 IDPSRTRMSK MARKDPTIEF CQLGLDTFET KYITMFGMLV SCSFDKPAFI SFVFSDFTKN 60
61 DIVQNYLYDR YLIDYENKLE LNEGFKAIMY KNQFETFDSK LRKIFNNGLR DLQNGRDENL 120
121 SQYGIVCKMN IKVKMYNGKL NAIVRECEPV P
|
| Detection Method: | |
| Confidence: | 1276.0 |
| Match: | 1kxlA_ |
| Description: | CDC13 ssDNA-binding domain |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [642-744] |
1 11 21 31 41 51
| | | | | |
1 HSQISSIASP SQCEHLRLFY QRAFKRIGES AISRYFEEYR RFFPIHRNGS HLAKLRFDEV 60
61 KHEPKKSPTT PALAEHIPDL NADVSSFDVK FTDISSLLDS SAR
|
| Detection Method: | |
| Confidence: | 1276.0 |
| Match: | 1kxlA_ |
| Description: | CDC13 ssDNA-binding domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [745-924] |
1 11 21 31 41 51
| | | | | |
1 LPRPQQTHKS NTLYSCEGRI IAIEYHASDL CFHITNELPL LQTRGLAPER VLQLHIITSK 60
61 NFAYFFNRSS AYLQRQPLEE KYTQLAQFLG HSFKFNITSS LTLFPDTTVA LQIWCPIECT 120
121 FRELQQQLAH PKVAAAPDSG SLDCAINATV NPLRLLAAQN GVTVKKEEDN DDDAGAVPTS 180
181
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| telomerase inhibitor activity | 8.08322438894165 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 7.13197590913268 | bayes_pls_golite062009 |
| telomeric DNA binding | 7.07761964836826 | bayes_pls_golite062009 |
| nucleic acid binding | 3.99127970564994 | bayes_pls_golite062009 |
| DNA binding | 3.53568546959418 | bayes_pls_golite062009 |
| structure-specific DNA binding | 3.06066809614422 | bayes_pls_golite062009 |
| single-stranded DNA binding | 3.0183551365402 | bayes_pls_golite062009 |
| DEAD/H-box RNA helicase binding | 2.8741276864403 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.13063800565247 | bayes_pls_golite062009 |
| structural molecule activity | 1.9177190829469 | bayes_pls_golite062009 |
| transcription regulator activity | 1.84350127337404 | bayes_pls_golite062009 |
| DNA helicase activity | 1.12203697857261 | bayes_pls_golite062009 |
| transcription factor activity | 0.952569279670437 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.85691075793641 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.638831894247026 | bayes_pls_golite062009 |
| ribonuclease activity | 0.62994126331969 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| translation regulator activity | 0.515576958825022 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.491028860958185 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.468402630523277 | bayes_pls_golite062009 |
| exonuclease activity | 0.28313884527829 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.2080607201312 | bayes_pls_golite062009 |
| protein binding | 0.152645195799531 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 0.10868826895563 | bayes_pls_golite062009 |
| RNA polymerase activity | 0.10868826895563 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0179535526984695 | bayes_pls_golite062009 |
| helicase activity | 0.0121541775159524 | bayes_pls_golite062009 |
|
Region A: Residues: [706-924] |
1 11 21 31 41 51
| | | | | |
1 KKSPTTPALA EHIPDLNADV SSFDVKFTDI SSLLDSSARL PRPQQTHKSN TLYSCEGRII 60
61 AIEYHASDLC FHITNELPLL QTRGLAPERV LQLHIITSKN FAYFFNRSSA YLQRQPLEEK 120
121 YTQLAQFLGH SFKFNITSSL TLFPDTTVAL QIWCPIECTF RELQQQLAHP KVAAAPDSGS 180
181 LDCAINATVN PLRLLAAQNG VTVKKEEDND DDAGAVPTS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
