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View Structure Prediction Details

Protein: gi|60817675, gi|...
Organism: synthetic construct
Length: 194 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|60817675, gi|....

Description E-value Query
Range		 Subject
Range
KAD1_RAT - Adenylate kinase isoenzyme 1 OS=Rattus norvegicus GN=Ak1 PE=1 SV=3
 1.0E-44 [1..194] [1..194]
gi|230801 - gi|230801|pdb|3ADK| Chain , Adenylate Kinase (E.C.2.7.4.3)
 1.0E-44 [1..194] [2..195]
gi|109112204 - gi|109112204|ref|XP_001094708.1| PREDICTED: adenylate kinase 1 [Macaca mulatta]
 2.0E-44 [1..194] [1..194]
gi|61365690 - gi|61365690|gb|AAX42747.1| adenylate kinase 1 [synthetic construct]
 2.0E-44 [1..194] [1..194]
KAD1_BOVIN - Adenylate kinase isoenzyme 1 OS=Bos taurus GN=AK1 PE=1 SV=2
 3.0E-44 [1..194] [1..194]
KAD1_RABIT - Adenylate kinase isoenzyme 1 OS=Oryctolagus cuniculus GN=AK1 PE=1 SV=1
 5.0E-44 [1..194] [1..194]

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Predicted Domain #1
Region A:
Residues: [1-194] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEKLKKTKI IFVVGGPGSG KGTQCEKIVQ KYGYTHLSTG DLLRSEVSSG SARGKKLSEI  60
   61 MEKGQLVPLE TVLDMLRDAM VAKVNTSKGF LIDGYPREVQ QGEEFERRIG QPTLLLYVDA 120
  121 GPETMTQRLL KRGETSGRVD DNEETIKKRL ETYYKATEPV IAFYEKRGIV RKVNAEGSVD 180
  181 SVFSQVCTHL DALK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 3adkA
Description: REFINED STRUCTURE OF PORCINE CYTOSOLIC ADENYLATE KINASE AT 2.1 ANGSTROMS RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 5.63633783771436 bayes_pls_golite062009
nucleotide kinase activity 4.87013305162694 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 4.71956130169341 bayes_pls_golite062009
adenylate kinase activity 3.67594732794865 bayes_pls_golite062009
transporter activity 3.06347241703095 bayes_pls_golite062009
transmembrane transporter activity 2.92178249124988 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.72471277217637 bayes_pls_golite062009
pyrophosphatase activity 2.65178178494722 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.6324074638534 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.62930532133361 bayes_pls_golite062009
active transmembrane transporter activity 2.47371672314006 bayes_pls_golite062009
primary active transmembrane transporter activity 2.36656376979386 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.36628513972722 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.33101326378731 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.32956222649229 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.32729839766053 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 2.29455092461489 bayes_pls_golite062009
ATPase activity 2.23432662573776 bayes_pls_golite062009
ATPase activity, coupled 2.22021172695288 bayes_pls_golite062009
nucleic acid binding 2.11222585187695 bayes_pls_golite062009
DNA binding 1.7904783386531 bayes_pls_golite062009
transcription regulator activity 1.68903321260301 bayes_pls_golite062009
substrate-specific transporter activity 1.62497652645669 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 1.39044805677656 bayes_pls_golite062009
hydrolase activity 1.32740066346416 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.28936854749141 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.27520023113176 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
guanylate kinase activity 0.98934362137863 bayes_pls_golite062009
purine nucleotide binding 0.912853112793192 bayes_pls_golite062009
nucleotide binding 0.905342574142397 bayes_pls_golite062009
purine ribonucleotide binding 0.904115761720541 bayes_pls_golite062009
ribonucleotide binding 0.904053997411779 bayes_pls_golite062009
GTPase activity 0.83849854735032 bayes_pls_golite062009
structural constituent of ribosome 0.738234102557832 bayes_pls_golite062009
protein transporter activity 0.712797684532763 bayes_pls_golite062009
motor activity 0.70874549510465 bayes_pls_golite062009
ion transmembrane transporter activity 0.678463776360409 bayes_pls_golite062009
transcription factor activity 0.603758349693077 bayes_pls_golite062009
CTP synthase activity 0.554689818807922 bayes_pls_golite062009
microtubule motor activity 0.48522137429998 bayes_pls_golite062009
ATP binding 0.38929752840764 bayes_pls_golite062009
adenyl ribonucleotide binding 0.364108656344062 bayes_pls_golite062009
adenyl nucleotide binding 0.356069365520539 bayes_pls_golite062009
translation regulator activity 0.29096092258568 bayes_pls_golite062009
translation factor activity, nucleic acid binding 0.274994961137851 bayes_pls_golite062009
cation transmembrane transporter activity 0.256834704602307 bayes_pls_golite062009
formate-tetrahydrofolate ligase activity 0.21533099279384 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
structural molecule activity 0.0558641287316701 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle