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View Structure Prediction Details

Protein: CE38104
Organism: Caenorhabditis elegans
Length: 492 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CE38104.

Description E-value Query
Range
Subject
Range
gi|186464325, gi... - gi|23128981|ref|ZP_00110817.1| COG2319: FOG: WD40 repeat [Nostoc punctiforme PCC 73102], gi|18668187...
563.0 [0..9] [491..1160]

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Predicted Domain #1
Region A:
Residues: [1-67]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFVCGISGE LTEDPVVSQV SGHIFDRRLI VKFIAENGTD PISHGELSED QLVSLKSGGT  60
   61 GSAPRNV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.522879
Match: 1n87A
Description: Pre-mRNA splicing factor Prp19
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 10.2497392096259 bayes_pls_golite062009
small conjugating protein ligase activity 10.0460587929138 bayes_pls_golite062009
acid-amino acid ligase activity 8.99384576623969 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 7.6988425139962 bayes_pls_golite062009
4.77196423114965 bayes_pls_golite062009
ligase activity 4.65189154176918 bayes_pls_golite062009
RNA binding 3.04658201081989 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
transcription regulator activity 2.72498741013971 bayes_pls_golite062009
protein binding 2.64803540957326 bayes_pls_golite062009
nucleic acid binding 2.32387297115017 bayes_pls_golite062009
DNA binding 2.00904221080834 bayes_pls_golite062009
transcription repressor activity 1.98209395225978 bayes_pls_golite062009
SMAD binding 1.93335489484338 bayes_pls_golite062009
ubiquitin-ubiquitin ligase activity 1.37401357060257 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 1.34503687064945 bayes_pls_golite062009
transcription factor activity 1.22579085356684 bayes_pls_golite062009
small conjugating protein-specific protease activity 1.2126425713931 bayes_pls_golite062009
transcription factor binding 1.11842175076436 bayes_pls_golite062009
ubiquitin-specific protease activity 1.03469202541773 bayes_pls_golite062009
copper ion binding 0.649716953783871 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
cysteine-type peptidase activity 0.50197530717959 bayes_pls_golite062009
transcription corepressor activity 0.384990496120483 bayes_pls_golite062009
SUMO polymer binding 0.33041248422054 bayes_pls_golite062009
cation binding 0.27118370366296 bayes_pls_golite062009
metal ion binding 0.27118370366296 bayes_pls_golite062009
ubiquitin thiolesterase activity 0.265769062717221 bayes_pls_golite062009
ion binding 0.265633945008889 bayes_pls_golite062009
transcription cofactor activity 0.233838999434784 bayes_pls_golite062009
transition metal ion binding 0.219773564054437 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
transcription activator activity 0.126093965701234 bayes_pls_golite062009
enzyme binding 0.104373352314595 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [68-156]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTSIPSLLK MLQDEWDTVM LNSFSLRQQL QIARQELSHS LYQHDAACRV ISRLSKELTA  60
   61 AREALSTLKP HTSAKVDDDV SIDESEDQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 34.221849
Match: 2pm7B
Description: No description for 2pm7B was found.

Predicted Domain #3
Region A:
Residues: [157-492]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSEAILAKL EEKSKSLTAE RKQRGKNLPE GLAKTEELAE LKQTASHTGI HSTGTPGITA  60
   61 LDIKGNLSLT GGIDKTVVLY DYEKEQVMQT FKGHNKKINA VVLHPDNITA ISASADSHIR 120
  121 VWSATDSSSK AIIDVHQAPV TDISLNASGD YILSASDDSY WAFSDIRSGK SLCKVSVEPG 180
  181 SQIAVHSIEF HPDGLIFGTG AADAVVKIWD LKNQTVAAAF PGHTAAVRSI AFSENGYYLA 240
  241 TGSEDGEVKL WDLRKLKNLK TFANEEKQPI NSLSFDMTGT FLGIGGQKVQ VLHVKSWSEV 300
  301 VSLSDHSGPV TGVRFGENAR SLVTCSLDKS LRVFSF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 74.0
Match: 1gg2B
Description: beta1-subunit of the signal-transducing G protein heterotrimer
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ubiquitin-protein ligase activity 7.6976390971701 bayes_pls_golite062009
small conjugating protein ligase activity 7.38724968585043 bayes_pls_golite062009
6.67009948605948 bayes_pls_golite062009
acid-amino acid ligase activity 6.41826641115519 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 5.36089569430187 bayes_pls_golite062009
GTPase activity 4.02994814377904 bayes_pls_golite062009
RNA binding 3.77273677738815 bayes_pls_golite062009
snoRNA binding 2.69983094099712 bayes_pls_golite062009
structural molecule activity 2.6914565031145 bayes_pls_golite062009
ligase activity 2.55043310798974 bayes_pls_golite062009
binding 2.42570478946173 bayes_pls_golite062009
transcription regulator activity 2.3610959773142 bayes_pls_golite062009
nucleic acid binding 2.30918780727915 bayes_pls_golite062009
translation initiation factor activity 2.29806492548141 bayes_pls_golite062009
transcription repressor activity 2.29049708962212 bayes_pls_golite062009
protein binding 2.26925404328312 bayes_pls_golite062009
dynactin binding 2.07556426531897 bayes_pls_golite062009
DNA binding 1.71685536470455 bayes_pls_golite062009
transcription corepressor activity 1.41752877005447 bayes_pls_golite062009
cytoskeletal protein binding 1.26395898062853 bayes_pls_golite062009
transporter activity 1.17433526848815 bayes_pls_golite062009
receptor activity 1.12819778129653 bayes_pls_golite062009
G-protein-coupled receptor binding 1.11754260203517 bayes_pls_golite062009
actin binding 1.08902852052152 bayes_pls_golite062009
transcription factor activity 1.08768505897883 bayes_pls_golite062009
mRNA binding 1.05053985350578 bayes_pls_golite062009
actin filament binding 0.976656531652978 bayes_pls_golite062009
molecular transducer activity 0.974380908248463 bayes_pls_golite062009
signal transducer activity 0.974380908248463 bayes_pls_golite062009
type 1 angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
angiotensin receptor binding 0.920323565472959 bayes_pls_golite062009
kinase activity 0.807669232329985 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.805273887494167 bayes_pls_golite062009
substrate-specific transporter activity 0.703671430935754 bayes_pls_golite062009
dynein binding 0.67053085134802 bayes_pls_golite062009
protein transporter activity 0.644350648477191 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.634547834947756 bayes_pls_golite062009
protein kinase activity 0.544118712921054 bayes_pls_golite062009
transcription factor binding 0.489473003915035 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 0.446034974847705 bayes_pls_golite062009
tubulin binding 0.418259033722167 bayes_pls_golite062009
microtubule binding 0.360612852884949 bayes_pls_golite062009
transcription cofactor activity 0.30761651528651 bayes_pls_golite062009
hydrolase activity 0.181211933860468 bayes_pls_golite062009
enzyme regulator activity 0.161639372576406 bayes_pls_golite062009
protein serine/threonine kinase activity 0.0803897416817422 bayes_pls_golite062009
receptor binding 0.0390635451962911 bayes_pls_golite062009
kinase binding 0.0366162235750993 bayes_pls_golite062009
protein kinase binding 0.00858004043229577 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle