YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30263916, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	491 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30263916, gi|....

Description	E-value	Query Range	Subject Range
gi\|229129192, gi... - gi\|229129192\|ref\|ZP_04258165.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|228637119, gi... - gi\|229146486\|ref\|ZP_04274857.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|228723846, gi... - gi\|229047599\|ref\|ZP_04193189.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... MURE_BACCR - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase OS=Bacillus cereus (strain ATC...	0.0	[1..491]	[1..491]
gi\|51975043, gi\|... - gi\|52141574\|ref\|YP_085255.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Bac...	0.0	[1..491]	[1..491]
gi\|228660204, gi... - gi\|229123428\|ref\|ZP_04252632.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|228947634, gi... - gi\|228947634\|ref\|ZP_04109924.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|228830770, gi... - gi\|228928963\|ref\|ZP_04091995.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|228843131, gi... - gi\|228916552\|ref\|ZP_04080118.1\| UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate liga... gi\|49481794, gi\|... - gi\|49481794\|ref\|YP_037976.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [Bac... gi\|254721449 - gi\|254721449\|ref\|ZP_05183238.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [... gi\|218535272, gi... - gi\|218905045\|ref\|YP_002452879.1\| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate ligase [B... gi\|196035932, gi... - gi\|196035932\|ref\|ZP_03103334.1\| UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate ligase [Ba...	0.0	[1..491]	[1..491]
gi\|42781669, gi\|... - gi\|42781669\|ref\|NP_978916.1\| UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate ligase [Baci...	0.0	[1..486]	[1..492]
gi\|21401899, gi\|... - gi\|65321241\|ref\|ZP_00394200.1\| COG0769: UDP-N-acetylmuramyl tripeptide synthase [Bacillus anthracis ...	0.0	[1..491]	[1..491]
gi\|47565786, gi\|... - gi\|47565786\|ref\|ZP_00236825.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [B...	0.0	[1..491]	[1..491]
MURE1_CLOAB - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 1 OS=Clostridium acetobutylicu... MURE1_CLOAB, MUE... - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase 1 OS=Clostridium acetobutylicu...	0.0	[1..487]	[1..482]
gi\|221318640 - gi\|221318640\|ref\|ZP_03599934.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [... gi\|221313717 - gi\|221313717\|ref\|ZP_03595522.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [... MURE_BACSU - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase OS=Bacillus subtilis GN=murE P... MURE_BACSU - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase OS=Bacillus subtilis (strain 1... gi\|221322914 - gi\|221322914\|ref\|ZP_03604208.1\| UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase [...	0.0	[18..490]	[19..491]

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Predicted Domain #1

Region A:
Residues: [1-491]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLHTLVSCL HDFPVVPKEN PEITSIEADS RKVKEGSLFV CMKGYTVDSH DFAKQAAAQG  60
   61 AAAIVAERPI DVDVPVVLVK NTFRSLAVLA DYFYGQPTHK LHLIGITGTN GKTTTSHIMD 120
  121 EIMRAHGHKT GLIGTINMKI GDETFEVKNT TPDALTLQQT FAKMVEHGVD STVMEVSSHA 180
  181 LDLGRVHGCD YDVAVFTNLT QDHLDYHKTM EEYKHAKGLL FAQLGNSYNH NREKYAVLNN 240
  241 DDAVTVEYMR STAATVVTYG IDTTSDVMAK DIAMTSGGTT FTLVTPYESV NVTMKLIGKF 300
  301 NVYNVLAATA AGLVSGVSLE TIIDVIKELA GVPGRFEVVD GGQNYTVIVD YAHTPDSLEN 360
  361 VLKTAKQFAK GDVYCIVGCG GDRDRTKRPI MASVATQYAT HAIYTSDNPR SEDPAAILDD 420
  421 MVHGANGNNY EVIIDRKEAI HHAITKAKAD DIIIIAGKGH ETYQIIGKDV HHFDDREVAK 480
  481 EAITERLNNE E

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	82.0
Match:	1e8cA
Description:	UDP-N-acetylmuramyl tripeptide synthetase MurE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acid-amino acid ligase activity	4.86493054281191	bayes_pls_golite062009
catalytic activity	3.03081854683329	bayes_pls_golite062009
UDP-N-acetylmuramate-L-alanine ligase activity	2.62956763198067	bayes_pls_golite062009
UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	2.38541436302257	bayes_pls_golite062009
ligase activity	2.2556848409907	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	2.19206014001612	bayes_pls_golite062009
UDP-N-acetylmuramoylalanine-D-glutamate ligase activity	1.471039191151	bayes_pls_golite062009
UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	1.15437935952018	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: