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Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate. Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
Acc: GO:0008764
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.
Synonyms:
  • MurD synthetase activity
  • uridine diphospho-N-acetylmuramoylalanyl-D-glutamate synthetase activity
  • D-glutamate ligase activity
  • D-glutamate-adding enzyme activity
  • UDP-N-acetylmuramoyl-L-alanine:glutamate ligase (ADP-forming)
  • UDP-Mur-NAC-L-Ala:D-Glu ligase activity
  • UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase activity
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008764 - UDP-N-acetylmuramoylalanine-D-glutamate ligase activity (interactive image map)
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