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Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine. Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate. Catalysis of the ligation of two substances via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: UDP-N-acetylmuramate-L-alanine ligase activity
Acc: GO:0008763
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl + L-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanine.
Synonyms:
  • UDP-N-acetylmuramoylalanine synthetase activity
  • MurC synthetase activity
  • UDP-N-acetylmuramoyl-L-alanine synthetase activity
  • UDP-N-acetylmuramyl:L-alanine ligase activity
  • UDP-N-acetylmuramate:L-alanine ligase (ADP-forming)
  • uridine diphosphate N-acetylmuramate:L-alanine ligase activity
  • alanine-adding enzyme activity
  • uridine 5'-diphosphate-N-acetylmuramyl-L-alanine synthetase activity
  • uridine-diphosphate-N-acetylmuramate:L-alanine ligase activity
  • L-alanine-adding enzyme activity
  • UDP-acetylmuramyl-L-alanine synthetase activity
  • uridine diphospho-N-acetylmuramoylalanine synthetase activity
  • L-Ala ligase activity
  • UDP-MurNAc:L-alanine ligase activity
  • UDPMurNAc-L-alanine synthetase activity
Proteins in PDR annotated with:
   This term: 9 [Search]
   Term or descendants: 9 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008763 - UDP-N-acetylmuramate-L-alanine ligase activity (interactive image map)
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