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View Structure Prediction Details

Protein: gi|190689465, gi...
Organism: synthetic construct
Length: 346 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|190689465, gi....

Description E-value Query
Range		 Subject
Range
gi|109130943 - gi|109130943|ref|XP_001094192.1| PREDICTED: similar to Ras-related GTP binding B short isoform isofo...
 4.0E-75 [1..346] [1..346]
gi|74007059 - gi|74007059|ref|XP_549027.2| PREDICTED: similar to Ras-related GTP binding B short isoform isoform 1...
 1.0E-74 [1..345] [1..345]
gi|114688826 - gi|114688826|ref|XP_529001.2| PREDICTED: hypothetical protein isoform 2 [Pan troglodytes]
 2.0E-74 [1..346] [1..346]
RRAGB - Ras-related GTP binding B
 1.0E-71 [1..346] [1..374]
gi|115497160, gi... - gi|115497160|ref|NP_001068747.1| Ras-related GTP binding B [Bos taurus], gi|109658285|gb|AAI18273.1|...
 9.0E-71 [1..346] [1..374]
RRAGB_MOUSE - Ras-related GTP-binding protein B OS=Mus musculus GN=Rragb PE=2 SV=1
RRAGB_RAT - Ras-related GTP-binding protein B OS=Rattus norvegicus GN=RragB PE=1 SV=1
 2.0E-70 [1..346] [1..374]

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Predicted Domain #1
Region A:
Residues: [1-346] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEESDSEKTT EKENLGPRMD PPLGEPEGSL GWVLPNTAMK KKVLLMGKSG SGKTSMRSII  60
   61 FANYIARDTR RLGATIDVEH SHVRFLGNLV LNLWDCGGQD TFMENYFTSQ RDNIFRNVEV 120
  121 LIYVFDVESR ELEKDMHYYQ SCLEAILQNS PDAKIFCLVH KMDLVQEDQR DLIFKEREED 180
  181 LRRLSRPLEC SCFRTSIWDE TLYKAWSSIV YQLIPNVQQL EMNLRNFAEI IEADEVLLFE 240
  241 RATFLVISHY QCKEQRDAHR FEKISNIIKQ FKLSCSKLAA SFQSMEVRNS NFAAFIDIFT 300
  301 SNTYVMVVMS DPSIPSAATL INIRNARKHF EKLERVDGPK QCLLMR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1g7rA
Description: Initiation factor IF2/eIF5b, domains 2 and 4; Initiation factor IF2/eIF5b, domain 3; Initiation factor IF2/eIF5b, N-terminal (G) domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
substrate-specific transmembrane transporter activity 3.23874001886507 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
ion transmembrane transporter activity 3.0820581259376 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
anion transmembrane transporter activity 2.9347445186951 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
hydrolase activity 2.65461298232951 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
nucleic acid binding 2.51683451033161 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
primary active transmembrane transporter activity 2.39629638016861 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.39600931083427 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
cation transmembrane transporter activity 2.37050194124695 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.36051733655256 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.35906629925754 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.35679406876731 bayes_pls_golite062009
ATPase activity, coupled 2.24901251684901 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 2.13337723998035 bayes_pls_golite062009
DNA binding 2.12258000781149 bayes_pls_golite062009
transcription regulator activity 2.09345198747025 bayes_pls_golite062009
guanyl nucleotide binding 1.89320355239381 bayes_pls_golite062009
guanyl ribonucleotide binding 1.88721318481223 bayes_pls_golite062009
GTP binding 1.87900088157196 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 1.84325261964383 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 1.83918646305011 bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism 1.68007728466043 bayes_pls_golite062009
substrate-specific transporter activity 1.65609907941094 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions 1.23799860254751 bayes_pls_golite062009
GTPase activity 1.23010905798386 bayes_pls_golite062009
protein binding 1.22129154759482 bayes_pls_golite062009
metal ion transmembrane transporter activity 1.05000823625983 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 1.02454765232944 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
phosphate transmembrane transporter activity 0.984780040772665 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
transcription factor activity 0.887108427603557 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 0.875516896523362 bayes_pls_golite062009
transcription repressor activity 0.862685397469217 bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity 0.85084700517845 bayes_pls_golite062009
cation-transporting ATPase activity 0.479313416848205 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
transmembrane receptor activity 0.253362378952397 bayes_pls_golite062009
signal transducer activity 0.235197013475539 bayes_pls_golite062009
molecular transducer activity 0.235197013475539 bayes_pls_golite062009
receptor activity 0.199649668891818 bayes_pls_golite062009
copper ion transmembrane transporter activity 0.194557482955115 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
motor activity 0.0492636236578701 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle