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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.0749965632]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF ubiquitin ligase complex 2.779E-6 2 11 2 6292
cullin-RING ubiquitin ligase complex 4.5979E-6 2 14 2 6292
ubiquitin ligase complex 4.5626E-5 2 43 2 6292
cellular bud neck contractile ring 5.7138E-3 2 18 1 6292
actomyosin contractile ring 5.7138E-3 2 18 1 6292
contractile ring 5.7138E-3 2 18 1 6292
nuclear ubiquitin ligase complex 7.2981E-3 2 23 1 6292
cell division site 8.5646E-3 2 27 1 6292
cell division site part 8.5646E-3 2 27 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
cellular protein catabolic process 7.3441E-4 2 171 2 6292
proteolysis 8.8816E-4 2 188 2 6292
protein catabolic process 8.9766E-4 2 189 2 6292
response to DNA damage stimulus 1.4011E-3 2 236 2 6292
cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
cellular response to stress 2.1173E-3 2 290 2 6292
macromolecule catabolic process 2.1762E-3 2 294 2 6292
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 2.224E-3 2 7 1 6292
cell cycle arrest in response to pheromone 2.5415E-3 2 8 1 6292
cell cycle arrest 3.4937E-3 2 11 1 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
cellular catabolic process 4.3405E-3 2 415 2 6292
catabolic process 6.2027E-3 2 496 2 6292
response to stress 6.2277E-3 2 497 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ubiquitin-protein ligase activity 8.0641E-5 2 57 2 6292
small conjugating protein ligase activity 9.5546E-5 2 62 2 6292
acid-amino acid ligase activity 1.2556E-4 2 71 2 6292
ligase activity, forming carbon-nitrogen bonds 2.2085E-4 2 94 2 6292
ligase activity 5.6464E-4 2 150 2 6292
protein binding 9.4468E-3 2 612 2 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle