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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Msi1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromatin assembly complex 1.9966E-5 4 12 2 6292
chromatin silencing complex 5.7106E-3 4 9 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nucleosome assembly 3.6271E-5 4 16 2 6292
chromatin assembly 5.1654E-5 4 19 2 6292
nucleosome organization 1.2238E-4 4 29 2 6292
DNA packaging 1.4941E-4 4 32 2 6292
chromatin assembly or disassembly 1.7912E-4 4 35 2 6292
protein-DNA complex assembly 2.2288E-4 4 39 2 6292
DNA conformation change 4.952E-4 4 58 2 6292
negative regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
gene silencing 1.4697E-3 4 100 2 6292
regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
chromatin silencing 1.4697E-3 4 100 2 6292
negative regulation of transcription, DNA-dependent 3.5916E-3 4 157 2 6292
negative regulation of RNA metabolic process 3.6369E-3 4 158 2 6292
negative regulation of transcription 3.9142E-3 4 164 2 6292
negative regulation of gene expression 3.9142E-3 4 164 2 6292
negative regulation of macromolecule biosynthetic process 4.4481E-3 4 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.7016E-3 4 180 2 6292
negative regulation of nitrogen compound metabolic process 4.7016E-3 4 180 2 6292
cellular macromolecular complex assembly 4.8049E-3 4 182 2 6292
negative regulation of biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of cellular biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of macromolecule metabolic process 5.3374E-3 4 192 2 6292
chromatin organization 5.954E-3 4 203 2 6292
negative regulation of cellular metabolic process 6.3039E-3 4 209 2 6292
negative regulation of metabolic process 6.3631E-3 4 210 2 6292
negative regulation of cellular process 8.9471E-3 4 250 2 6292
negative regulation of biological process 9.1576E-3 4 253 2 6292
cellular macromolecular complex subunit organization 9.5855E-3 4 259 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

carnitine:acyl carnitine antiporter activity 6.3573E-4 4 1 1 6292
solute:solute antiporter activity 5.0773E-3 4 8 1 6292
antiporter activity 5.7106E-3 4 9 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle