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The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent. A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule. Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. The process by which a cellular component is synthesized, aggregates, and bonds together. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin. The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA. Any process by which DNA and associated proteins are formed into a compact, orderly structure. The formation or destruction of chromatin structures. The assembly of chromatin into the specialized structure characteristic of the centromeric core region, defined by the presence of the variant histone CENP-A. The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus. The aggregation, arrangement and bonding together of a cellular component. Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: chromatin assembly
Acc: GO:0031497
Aspect: Biological Process
Desc: The assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
Synonyms:
  • establishment of chromatin architecture
Proteins in PDR annotated with:
   This term: 8 [Search]
   Term or descendants: 379 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0031497 - chromatin assembly (interactive image map)
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