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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Shs1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ACC1
  • endoplasmic reticulum membrane
  • mitochondrion
  • cytosol
  • nuclear envelope organization
  • protein import into nucleus
  • fatty acid biosynthetic process
  • acetyl-CoA carboxylase activity
  • biotin carboxylase activity
  • ARC35
  • cytosol
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • microtubule cytoskeleton organization
  • actin cytoskeleton organization
  • structural molecule activity
  • ARP2
  • mitochondrion
  • Arp2/3 protein complex
  • mitochondrion inheritance
  • actin filament organization
  • ATP binding
  • actin binding
  • structural constituent of cytoskeleton
  • BGL2
  • fungal-type cell wall
  • cellular cell wall organization
  • glucan 1,3-beta-glucosidase activity
  • KGD2
  • mitochondrial matrix
  • mitochondrial oxoglutarate dehydrogenase complex
  • mitochondrion
  • mitochondrial nucleoid
  • tricarboxylic acid cycle
  • 2-oxoglutarate metabolic process
  • dihydrolipoyllysine-residue succinyltransferase activity
  • LIA1
  • nucleus
  • cytoplasm
  • ribosome biogenesis
  • microtubule cytoskeleton organization
  • protein binding
  • deoxyhypusine monooxygenase activity
  • RPT4
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • ubiquitin-dependent protein catabolic process
  • ATPase activity
  • endopeptidase activity
  • RVB2
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • nuclear outer membrane
  • chromatin remodeling complex
  • chromatin remodeling
  • snoRNA metabolic process
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • SHS1
  • septin ring
  • cell morphogenesis
  • cytokinesis
  • structural constituent of cytoskeleton
  • YHR033W
  • cytoplasm
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    Arp2/3 protein complex 4.7546E-5 10 7 2 6292
    cytoskeletal part 3.2643E-3 10 201 3 6292
    cytoskeleton 4.004E-3 10 216 3 6292
    mitochondrial oxoglutarate dehydrogenase complex 4.7611E-3 10 3 1 6292
    oxoglutarate dehydrogenase complex 4.7611E-3 10 3 1 6292
    actin cytoskeleton 7.565E-3 10 85 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mitochondrion distribution 9.0222E-4 10 29 2 6292
    mitochondrion inheritance 9.0222E-4 10 29 2 6292
    mitochondrion localization 9.6584E-4 10 30 2 6292
    organelle inheritance 2.0756E-3 10 44 2 6292
    2-oxoglutarate metabolic process 3.1764E-3 10 2 1 6292
    cellular component organization 3.6048E-3 10 1582 7 6292
    cytoskeleton organization 4.8399E-3 10 231 3 6292
    organelle localization 7.565E-3 10 85 2 6292
    microtubule cytoskeleton organization 9.7663E-3 10 97 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    biotin carboxylase activity 1.5893E-3 10 1 1 6292
    dihydrolipoyllysine-residue succinyltransferase activity 1.5893E-3 10 1 1 6292
    S-succinyltransferase activity 1.5893E-3 10 1 1 6292
    deoxyhypusine monooxygenase activity 1.5893E-3 10 1 1 6292
    structural constituent of cytoskeleton 3.0005E-3 10 53 2 6292
    succinyltransferase activity 3.1764E-3 10 2 1 6292
    acetyl-CoA carboxylase activity 3.1764E-3 10 2 1 6292
    CoA carboxylase activity 3.1764E-3 10 2 1 6292
    ligase activity, forming carbon-carbon bonds 6.3436E-3 10 4 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle