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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Dmc1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 7 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ACC1
  • endoplasmic reticulum membrane
  • mitochondrion
  • cytosol
  • nuclear envelope organization
  • protein import into nucleus
  • fatty acid biosynthetic process
  • acetyl-CoA carboxylase activity
  • biotin carboxylase activity
  • DMC1
  • nucleus
  • condensed nuclear chromosome
  • meiotic joint molecule formation
  • reciprocal meiotic recombination
  • meiosis
  • double-stranded DNA binding
  • single-stranded DNA binding
  • DPM1
  • mitochondrion
  • nuclear membrane-endoplasmic reticulum network
  • endoplasmic reticulum
  • mitochondrial outer membrane
  • GPI anchor biosynthetic process
  • protein amino acid O-linked glycosylation
  • protein amino acid N-linked glycosylation
  • transferase activity, transferring glycosyl groups
  • dolichyl-phosphate beta-D-mannosyltransferase activity
  • MDJ1
  • mitochondrion
  • mitochondrial inner membrane
  • proteolysis
  • protein folding
  • chaperone binding
  • unfolded protein binding
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • RVB2
  • nucleus
  • Swr1 complex
  • Ino80 complex
  • nuclear outer membrane
  • chromatin remodeling complex
  • chromatin remodeling
  • snoRNA metabolic process
  • regulation of transcription from RNA polymerase II promoter
  • ATPase activity
  • ATP-dependent 5'-3' DNA helicase activity
  • TRP3
  • cytoplasm
  • anthranilate synthase complex
  • tryptophan biosynthetic process
  • indole-3-glycerol-phosphate synthase activity
  • anthranilate synthase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nuclear membrane-endoplasmic reticulum network 5.7767E-5 7 232 4 6292
    organelle membrane 2.7567E-4 7 692 5 6292
    endomembrane system 4.7362E-4 7 398 4 6292
    outer membrane 7.1655E-4 7 178 3 6292
    organelle outer membrane 7.1655E-4 7 178 3 6292
    envelope 1.1796E-3 7 505 4 6292
    organelle envelope 1.1796E-3 7 505 4 6292
    anthranilate synthase complex 2.224E-3 7 2 1 6292
    Noc4p-Nop14p complex 2.224E-3 7 2 1 6292
    membrane part 3.276E-3 7 662 4 6292
    membrane 3.7029E-3 7 1198 5 6292
    nuclear outer membrane 3.7089E-3 7 86 2 6292
    nuclear membrane 4.6971E-3 7 97 2 6292
    Noc complex 5.552E-3 7 5 1 6292
    preribosome, small subunit precursor 6.6592E-3 7 6 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    meiotic joint molecule formation 2.224E-3 7 2 1 6292
    primary metabolic process 4.3588E-3 7 2896 7 6292
    cellular metabolic process 6.026E-3 7 3033 7 6292
    nuclear envelope organization 7.7654E-3 7 7 1 6292
    metabolic process 7.9792E-3 7 3157 7 6292
    lipid biosynthetic process 8.3115E-3 7 130 2 6292
    organic acid biosynthetic process 9.4614E-3 7 139 2 6292
    carboxylic acid biosynthetic process 9.4614E-3 7 139 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    dolichyl-phosphate beta-D-mannosyltransferase activity 1.1125E-3 7 1 1 6292
    biotin carboxylase activity 1.1125E-3 7 1 1 6292
    indole-3-glycerol-phosphate synthase activity 1.1125E-3 7 1 1 6292
    anthranilate synthase activity 2.224E-3 7 2 1 6292
    acetyl-CoA carboxylase activity 2.224E-3 7 2 1 6292
    CoA carboxylase activity 2.224E-3 7 2 1 6292
    oxo-acid-lyase activity 4.4437E-3 7 4 1 6292
    ligase activity, forming carbon-carbon bonds 4.4437E-3 7 4 1 6292
    ATP-dependent 5'-3' DNA helicase activity 7.7654E-3 7 7 1 6292
    5'-3' DNA helicase activity 8.8705E-3 7 8 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle