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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc3. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AAT2
  • peroxisome
  • cytoplasm
  • glutamate metabolic process
  • nitrogen compound metabolic process
  • asparagine biosynthetic process from oxaloacetate
  • aspartate biosynthetic process
  • aspartate catabolic process
  • L-aspartate:2-oxoglutarate aminotransferase activity
  • CDC10
  • cellular bud neck septin ring
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • cell morphogenesis involved in conjugation with cellular fusion
  • ascospore wall assembly
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC11
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC12
  • cellular bud neck septin ring
  • cytoplasm
  • axial cellular bud site selection
  • bipolar cellular bud site selection
  • cell morphogenesis
  • conjugation with cellular fusion
  • cellular cell wall organization
  • cytokinesis
  • GTPase activity
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • CDC3
  • cellular bud neck septin ring
  • prospore membrane
  • ascospore wall
  • mating projection base
  • axial cellular bud site selection
  • cell morphogenesis
  • cellular cell wall organization
  • cytokinesis
  • structural constituent of cytoskeleton
  • phosphatidylinositol binding
  • HOM2
  • nucleus
  • cytoplasm
  • response to drug
  • methionine metabolic process
  • threonine metabolic process
  • homoserine biosynthetic process
  • aspartate-semialdehyde dehydrogenase activity
  • SHS1
  • septin ring
  • cell morphogenesis
  • cytokinesis
  • structural constituent of cytoskeleton
  • THR4
  • nucleus
  • cytoplasm
  • endocytosis
  • threonine metabolic process
  • threonine synthase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    septin ring 2.0415E-12 8 15 5 6292
    septin cytoskeleton 2.0415E-12 8 15 5 6292
    cellular bud neck septin structure 1.3484E-10 8 9 4 6292
    cellular bud neck septin ring 1.3484E-10 8 9 4 6292
    cleavage apparatus septin structure 1.3484E-10 8 9 4 6292
    cell division site 1.861E-8 8 27 4 6292
    cell division site part 1.861E-8 8 27 4 6292
    cell cortex part 4.0227E-8 8 96 5 6292
    cell cortex 7.6486E-8 8 109 5 6292
    cytoskeletal part 1.6401E-6 8 201 5 6292
    cytoskeleton 2.3444E-6 8 216 5 6292
    cellular bud neck 1.1079E-5 8 129 4 6292
    mating projection base 2.9615E-5 8 7 2 6292
    cellular bud 3.0119E-5 8 166 4 6292
    site of polarized growth 3.1578E-5 8 168 4 6292
    spore wall 6.3341E-5 8 10 2 6292
    ascospore wall 6.3341E-5 8 10 2 6292
    prospore membrane 2.3932E-4 8 19 2 6292
    intracellular immature spore 2.3932E-4 8 19 2 6292
    ascospore-type prospore 2.3932E-4 8 19 2 6292
    cell projection part 1.1875E-3 8 42 2 6292
    cell projection 1.6147E-3 8 49 2 6292
    mating projection 1.6147E-3 8 49 2 6292
    non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    intracellular non-membrane-bounded organelle 3.0487E-3 8 959 5 6292
    fungal-type cell wall 7.2337E-3 8 105 2 6292
    cell wall 7.3681E-3 8 106 2 6292
    external encapsulating structure 7.3681E-3 8 106 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    axial cellular bud site selection 2.516E-8 8 29 4 6292
    cytokinesis 8.7723E-8 8 112 5 6292
    cell morphogenesis 1.5256E-7 8 125 5 6292
    cellular component morphogenesis 2.5081E-7 8 138 5 6292
    cell division 3.2145E-7 8 145 5 6292
    cellular bud site selection 1.1912E-6 8 74 4 6292
    cytokinesis, site selection 1.1912E-6 8 74 4 6292
    cell cycle cytokinesis 1.6323E-6 8 80 4 6292
    establishment of cell polarity 1.9872E-6 8 84 4 6292
    establishment or maintenance of cell polarity 2.0843E-6 8 85 4 6292
    cell budding 2.6235E-6 8 90 4 6292
    asexual reproduction 2.6235E-6 8 90 4 6292
    cytokinetic process 2.866E-6 8 92 4 6292
    anatomical structure morphogenesis 5.5383E-6 8 257 5 6292
    anatomical structure development 5.8646E-6 8 260 5 6292
    cellular developmental process 7.8712E-6 8 276 5 6292
    aspartate family amino acid metabolic process 1.8675E-5 8 45 3 6292
    developmental process 1.9205E-5 8 331 5 6292
    cell wall organization 3.5454E-5 8 173 4 6292
    external encapsulating structure organization 3.5454E-5 8 173 4 6292
    cellular cell wall organization 3.5454E-5 8 173 4 6292
    threonine metabolic process 5.0705E-5 8 9 2 6292
    cell wall organization or biogenesis 7.3181E-5 8 208 4 6292
    cellular cell wall organization or biogenesis 7.3181E-5 8 208 4 6292
    reproduction of a single-celled organism 8.6392E-5 8 217 4 6292
    conjugation with cellular fusion 3.9856E-4 8 125 3 6292
    conjugation 4.0804E-4 8 126 3 6292
    reproduction 4.2948E-4 8 328 4 6292
    multi-organism process 5.9209E-4 8 143 3 6292
    bipolar cellular bud site selection 7.7767E-4 8 34 2 6292
    cellular amino acid metabolic process 1.5517E-3 8 199 3 6292
    cell cycle process 1.9742E-3 8 490 4 6292
    cellular amine metabolic process 2.1278E-3 8 222 3 6292
    sexual reproduction 2.4452E-3 8 233 3 6292
    cell cycle 2.5551E-3 8 525 4 6292
    amine metabolic process 2.7583E-3 8 243 3 6292
    cellular amino acid and derivative metabolic process 2.7583E-3 8 243 3 6292
    dicarboxylic acid catabolic process 3.8101E-3 8 3 1 6292
    homoserine biosynthetic process 3.8101E-3 8 3 1 6292
    aspartate metabolic process 3.8101E-3 8 3 1 6292
    aspartate biosynthetic process 3.8101E-3 8 3 1 6292
    aspartate catabolic process 3.8101E-3 8 3 1 6292
    asparagine biosynthetic process from oxaloacetate 3.8101E-3 8 3 1 6292
    oxaloacetate metabolic process 3.8101E-3 8 3 1 6292
    cellular component organization 4.336E-3 8 1582 6 6292
    asparagine biosynthetic process 6.3431E-3 8 5 1 6292
    carboxylic acid metabolic process 6.741E-3 8 333 3 6292
    organic acid metabolic process 6.741E-3 8 333 3 6292
    oxoacid metabolic process 6.741E-3 8 333 3 6292
    cellular ketone metabolic process 7.5041E-3 8 346 3 6292
    cellular amino acid biosynthetic process 8.4845E-3 8 114 2 6292
    homoserine metabolic process 8.8705E-3 8 7 1 6292
    asparagine metabolic process 8.8705E-3 8 7 1 6292
    amine biosynthetic process 9.6731E-3 8 122 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    phosphatidylinositol binding 2.2463E-10 8 10 4 6292
    structural constituent of cytoskeleton 1.9215E-9 8 53 5 6292
    phosphoinositide binding 6.9679E-8 8 37 4 6292
    phospholipid binding 1.298E-7 8 43 4 6292
    lipid binding 2.4136E-7 8 50 4 6292
    structural molecule activity 2.1584E-5 8 339 5 6292
    aspartate-semialdehyde dehydrogenase activity 1.2715E-3 8 1 1 6292
    threonine synthase activity 1.2715E-3 8 1 1 6292
    GTPase activity 2.4935E-3 8 61 2 6292
    L-aspartate:2-oxoglutarate aminotransferase activity 3.8101E-3 8 3 1 6292
    carbon-oxygen lyase activity, acting on phosphates 3.8101E-3 8 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle