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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Ufo1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 3 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF ubiquitin ligase complex 3.9763E-9 3 11 3 6292
cullin-RING ubiquitin ligase complex 8.7719E-9 3 14 3 6292
ubiquitin ligase complex 2.974E-7 3 43 3 6292
RAVE complex 1.4299E-3 3 3 1 6292
CBF3 complex 1.9063E-3 3 4 1 6292
protein complex 5.8881E-3 3 1137 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process 3.1815E-6 3 7 2 6292
protein ubiquitination during ubiquitin-dependent protein catabolic process 8.329E-6 3 11 2 6292
modification-dependent protein catabolic process 1.4956E-5 3 156 3 6292
ubiquitin-dependent protein catabolic process 1.4956E-5 3 156 3 6292
proteolysis involved in cellular protein catabolic process 1.5841E-5 3 159 3 6292
modification-dependent macromolecule catabolic process 1.7394E-5 3 164 3 6292
cellular protein catabolic process 1.9732E-5 3 171 3 6292
proteolysis 2.6264E-5 3 188 3 6292
protein catabolic process 2.6687E-5 3 189 3 6292
G2/M transition of mitotic cell cycle 6.1366E-5 3 29 2 6292
cellular macromolecule catabolic process 7.39E-5 3 265 3 6292
macromolecule catabolic process 1.0103E-4 3 294 3 6292
G1/S transition of mitotic cell cycle 1.8474E-4 3 50 2 6292
cellular catabolic process 2.85E-4 3 415 3 6292
protein ubiquitination 3.1318E-4 3 65 2 6292
proteasomal protein catabolic process 3.5308E-4 3 69 2 6292
proteasomal ubiquitin-dependent protein catabolic process 3.5308E-4 3 69 2 6292
catabolic process 4.8714E-4 3 496 3 6292
protein modification by small protein conjugation 5.4909E-4 3 86 2 6292
interphase of mitotic cell cycle 6.9865E-4 3 97 2 6292
interphase 6.9865E-4 3 97 2 6292
protein modification by small protein conjugation or removal 9.6474E-4 3 114 2 6292
centromere complex assembly 1.4299E-3 3 3 1 6292
kinetochore assembly 1.4299E-3 3 3 1 6292
kinetochore organization 1.4299E-3 3 3 1 6292
protein neddylation 3.3344E-3 3 7 1 6292
mitotic cell cycle 4.7773E-3 3 255 2 6292
cellular protein metabolic process 4.9618E-3 3 1074 3 6292
regulation of protein complex assembly 5.2364E-3 3 11 1 6292
protein metabolic process 5.8726E-3 3 1136 3 6292
regulation of cellular component biogenesis 8.5592E-3 3 18 1 6292
post-translational protein modification 9.2699E-3 3 357 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ubiquitin-protein ligase activity 7.0513E-7 3 57 3 6292
small conjugating protein ligase activity 9.1141E-7 3 62 3 6292
acid-amino acid ligase activity 1.3774E-6 3 71 3 6292
ligase activity, forming carbon-nitrogen bonds 3.2303E-6 3 94 3 6292
DNA replication origin binding 1.1809E-5 3 13 2 6292
ligase activity 1.3286E-5 3 150 3 6292
sequence-specific DNA binding 1.8474E-4 3 50 2 6292
protein binding 9.1614E-4 3 612 3 6292
DNA binding 4.8144E-3 3 256 2 6292
binding 8.6823E-3 3 1294 3 6292
protein binding, bridging 9.5071E-3 3 20 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle