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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Las17. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 11 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
AAC3
  • mitochondrion
  • mitochondrial inner membrane
  • anaerobic respiration
  • ATP:ADP antiporter activity
  • BZZ1
  • cytoplasm
  • actin cortical patch
  • response to salt stress
  • actin filament organization
  • endocytosis
  • molecular_function
  • HXT6
  • mitochondrion
  • plasma membrane
  • hexose transport
  • fructose transmembrane transporter activity
  • glucose transmembrane transporter activity
  • mannose transmembrane transporter activity
  • LAS17
  • cytoplasm
  • actin cortical patch
  • bipolar cellular bud site selection
  • actin polymerization or depolymerization
  • response to osmotic stress
  • cytokinesis
  • actin filament organization
  • endocytosis
  • cytoskeletal protein binding
  • MYO4
  • cellular bud
  • mitochondrion
  • myosin V complex
  • filamentous actin
  • intracellular mRNA localization
  • endoplasmic reticulum inheritance
  • gene conversion at mating-type locus
  • actin filament binding
  • microfilament motor activity
  • PEP1
  • Golgi apparatus
  • vacuolar transport
  • protein targeting to vacuole
  • signal sequence binding
  • RPN1
  • nucleus
  • proteasome regulatory particle, base subcomplex
  • cytoplasm
  • endoplasmic reticulum
  • ubiquitin-dependent protein catabolic process
  • endopeptidase activity
  • protein binding, bridging
  • RVS167
  • actin cortical patch
  • vesicle-mediated transport
  • bipolar cellular bud site selection
  • response to osmotic stress
  • endocytosis
  • cytoskeletal protein binding
  • SLA1
  • actin cortical patch
  • bipolar cellular bud site selection
  • cellular cell wall organization
  • actin filament organization
  • endocytosis
  • actin cortical patch assembly
  • ubiquitin binding
  • cytoskeletal protein binding
  • protein binding, bridging
  • VRP1
  • actin cortical patch
  • bipolar cellular bud site selection
  • response to osmotic stress
  • actin filament organization
  • endocytosis
  • actin binding
  • YNR065C
  • cellular_component
  • biological_process
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    actin cytoskeleton 2.2264E-9 11 85 6 6292
    actin cortical patch 4.1003E-9 11 41 5 6292
    cortical actin cytoskeleton 1.4096E-8 11 52 5 6292
    cortical cytoskeleton 1.4096E-8 11 52 5 6292
    cell cortex part 3.2002E-7 11 96 5 6292
    cytoskeletal part 3.9897E-7 11 201 6 6292
    cell cortex 6.053E-7 11 109 5 6292
    cytoskeleton 6.1126E-7 11 216 6 6292
    cytoplasmic part 6.3747E-4 11 2482 10 6292
    non-membrane-bounded organelle 2.8626E-3 11 959 6 6292
    intracellular non-membrane-bounded organelle 2.8626E-3 11 959 6 6292
    myosin V complex 3.4937E-3 11 2 1 6292
    filamentous actin 3.4937E-3 11 2 1 6292
    unconventional myosin complex 3.4937E-3 11 2 1 6292
    myosin complex 5.2364E-3 11 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    endocytosis 2.0643E-7 11 88 5 6292
    bipolar cellular bud site selection 2.2838E-7 11 34 4 6292
    membrane invagination 2.8785E-7 11 94 5 6292
    actin filament organization 3.8902E-6 11 68 4 6292
    cellular bud site selection 5.4669E-6 11 74 4 6292
    cytokinesis, site selection 5.4669E-6 11 74 4 6292
    response to osmotic stress 6.4125E-6 11 77 4 6292
    cell cycle cytokinesis 7.4742E-6 11 80 4 6292
    establishment of cell polarity 9.0857E-6 11 84 4 6292
    establishment or maintenance of cell polarity 9.5258E-6 11 85 4 6292
    cellular membrane organization 1.162E-5 11 198 5 6292
    membrane organization 1.162E-5 11 198 5 6292
    cell budding 1.1967E-5 11 90 4 6292
    asexual reproduction 1.1967E-5 11 90 4 6292
    cytokinetic process 1.3063E-5 11 92 4 6292
    reproduction of a single-celled organism 1.8172E-5 11 217 5 6292
    cytokinesis 2.8519E-5 11 112 4 6292
    actin cytoskeleton organization 2.9539E-5 11 113 4 6292
    actin filament-based process 3.3889E-5 11 117 4 6292
    response to abiotic stimulus 3.3889E-5 11 117 4 6292
    cell morphogenesis 4.3983E-5 11 125 4 6292
    cellular developmental process 5.8213E-5 11 276 5 6292
    localization 6.4656E-5 11 1060 8 6292
    cellular component morphogenesis 6.4873E-5 11 138 4 6292
    cell division 7.8741E-5 11 145 4 6292
    reproduction 1.3298E-4 11 328 5 6292
    developmental process 1.3886E-4 11 331 5 6292
    vesicle-mediated transport 1.5775E-4 11 340 5 6292
    transport 4.5033E-4 11 997 7 6292
    cytoskeleton organization 4.7654E-4 11 231 4 6292
    establishment of localization 4.8298E-4 11 1008 7 6292
    anatomical structure morphogenesis 7.1489E-4 11 257 4 6292
    anatomical structure development 7.4702E-4 11 260 4 6292
    endoplasmic reticulum inheritance 3.4937E-3 11 2 1 6292
    anaerobic respiration 3.4937E-3 11 2 1 6292
    cell cycle process 7.7055E-3 11 490 4 6292
    response to stress 8.1037E-3 11 497 4 6292
    cell cycle 9.8359E-3 11 525 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytoskeletal protein binding 2.7001E-8 11 59 5 6292
    protein binding 2.4899E-4 11 612 6 6292
    protein binding, bridging 5.1901E-4 11 20 2 6292
    actin binding 5.731E-4 11 21 2 6292
    binding 2.3113E-3 11 1294 7 6292
    ATP:ADP antiporter activity 5.2364E-3 11 3 1 6292
    microfilament motor activity 8.7135E-3 11 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle