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View Protein Complex Details

Complex Overview

From Publication: Gavin A.C. et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature. 2006 Mar 30;440(7084):631-6. Epub 2006 Jan 22.
Notes: From the published set of protein complexes (core proteins only)
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CFT1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mitochondrion
  • mRNA cleavage factor complex
  • termination of RNA polymerase II transcription
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • CFT2
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • FIP1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • protein binding
  • MPE1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • PAP1
  • mRNA cleavage and polyadenylation specificity factor complex
  • nucleoplasm
  • mRNA export from nucleus
  • mRNA polyadenylation
  • polynucleotide adenylyltransferase activity
  • PFS2
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • PTA1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • termination of RNA polymerase II transcription, poly(A)-coupled
  • tRNA processing
  • termination of RNA polymerase II transcription, poly(A)-independent
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • YSH1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA cleavage factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • endoribonuclease activity
  • YTH1
  • mRNA cleavage and polyadenylation specificity factor complex
  • mRNA polyadenylation
  • mRNA cleavage
  • RNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA cleavage and polyadenylation specificity factor complex 1.1818E-25 9 15 9 6292
    mRNA cleavage factor complex 3.966E-24 9 20 9 6292
    nucleoplasm part 1.7837E-13 9 245 9 6292
    nucleoplasm 3.5315E-13 9 264 9 6292
    nuclear lumen 4.8255E-11 9 453 9 6292
    organelle lumen 1.4638E-9 9 660 9 6292
    intracellular organelle lumen 1.4638E-9 9 660 9 6292
    membrane-enclosed lumen 2.4937E-9 9 700 9 6292
    nuclear part 1.5218E-7 9 1103 9 6292
    protein complex 2.0019E-7 9 1137 9 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    nucleus 3.9292E-5 9 2041 9 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    mRNA polyadenylation 2.1813E-24 9 19 9 6292
    RNA polyadenylation 7.378E-23 9 26 9 6292
    mRNA 3'-end processing 4.7604E-22 9 31 9 6292
    RNA 3'-end processing 1.0529E-20 9 42 9 6292
    mRNA cleavage 1.601E-19 9 25 8 6292
    nucleic acid phosphodiester bond hydrolysis 3.851E-17 9 46 8 6292
    mRNA processing 2.8146E-15 9 156 9 6292
    mRNA metabolic process 4.9477E-14 9 213 9 6292
    RNA processing 9.7721E-12 9 380 9 6292
    RNA metabolic process 4.101E-8 9 954 9 6292
    gene expression 5.9596E-7 9 1283 9 6292
    nucleic acid metabolic process 1.4425E-6 9 1415 9 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.6017E-6 9 1566 9 6292
    cellular nitrogen compound metabolic process 1.0872E-5 9 1770 9 6292
    nitrogen compound metabolic process 1.2092E-5 9 1791 9 6292
    cellular macromolecule metabolic process 1.0877E-4 9 2285 9 6292
    macromolecule metabolic process 1.3953E-4 9 2349 9 6292
    termination of RNA polymerase II transcription 3.0714E-4 9 19 2 6292
    transcription termination 3.7663E-4 9 21 2 6292
    primary metabolic process 9.2081E-4 9 2896 9 6292
    cellular protein complex disassembly 1.3113E-3 9 39 2 6292
    protein complex disassembly 1.3113E-3 9 39 2 6292
    cellular macromolecular complex disassembly 1.3793E-3 9 40 2 6292
    macromolecular complex disassembly 1.3793E-3 9 40 2 6292
    cellular metabolic process 1.3966E-3 9 3033 9 6292
    cellular component disassembly 1.6679E-3 9 44 2 6292
    metabolic process 2.004E-3 9 3157 9 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 1.0646E-9 9 367 8 6292
    nucleic acid binding 1.2385E-7 9 666 8 6292
    binding 2.3159E-5 9 1294 8 6292
    polynucleotide adenylyltransferase activity 8.5551E-3 9 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle