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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromatin assembly complex 2.1184E-8 4 12 3 6292
chromosome, centromeric region 6.6109E-4 4 67 2 6292
chromatin silencing complex 5.7106E-3 4 9 1 6292
chromosomal part 8.0617E-3 4 237 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

nucleosome assembly 5.3897E-8 4 16 3 6292
chromatin assembly 9.3228E-8 4 19 3 6292
nucleosome organization 3.5113E-7 4 29 3 6292
DNA packaging 4.7646E-7 4 32 3 6292
chromatin assembly or disassembly 6.2849E-7 4 35 3 6292
protein-DNA complex assembly 8.7717E-7 4 39 3 6292
DNA conformation change 2.9548E-6 4 58 3 6292
negative regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
gene silencing 1.5407E-5 4 100 3 6292
regulation of gene expression, epigenetic 1.5407E-5 4 100 3 6292
chromatin silencing 1.5407E-5 4 100 3 6292
negative regulation of transcription, DNA-dependent 5.987E-5 4 157 3 6292
negative regulation of RNA metabolic process 6.1021E-5 4 158 3 6292
negative regulation of transcription 6.8238E-5 4 164 3 6292
negative regulation of gene expression 6.8238E-5 4 164 3 6292
negative regulation of macromolecule biosynthetic process 8.2896E-5 4 175 3 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 9.0195E-5 4 180 3 6292
negative regulation of nitrogen compound metabolic process 9.0195E-5 4 180 3 6292
cellular macromolecular complex assembly 9.3229E-5 4 182 3 6292
negative regulation of biosynthetic process 1.0438E-4 4 189 3 6292
negative regulation of cellular biosynthetic process 1.0438E-4 4 189 3 6292
negative regulation of macromolecule metabolic process 1.0942E-4 4 192 3 6292
chromatin organization 1.2926E-4 4 203 3 6292
negative regulation of cellular metabolic process 1.4102E-4 4 209 3 6292
negative regulation of metabolic process 1.4305E-4 4 210 3 6292
negative regulation of cellular process 2.4072E-4 4 250 3 6292
negative regulation of biological process 2.4943E-4 4 253 3 6292
cellular macromolecular complex subunit organization 2.6748E-4 4 259 3 6292
macromolecular complex assembly 3.4098E-4 4 281 3 6292
macromolecular complex subunit organization 6.9425E-4 4 357 3 6292
regulation of transcription, DNA-dependent 7.0003E-4 4 358 3 6292
regulation of RNA metabolic process 7.294E-4 4 363 3 6292
regulation of transcription 8.6159E-4 4 384 3 6292
cellular component assembly 8.6824E-4 4 385 3 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 1.084E-3 4 415 3 6292
regulation of nitrogen compound metabolic process 1.0917E-3 4 416 3 6292
regulation of gene expression 1.3321E-3 4 445 3 6292
regulation of macromolecule biosynthetic process 1.4316E-3 4 456 3 6292
regulation of cellular biosynthetic process 1.5848E-3 4 472 3 6292
regulation of biosynthetic process 1.5947E-3 4 473 3 6292
regulation of macromolecule metabolic process 1.7483E-3 4 488 3 6292
transcription, DNA-dependent 1.9112E-3 4 503 3 6292
RNA biosynthetic process 1.9676E-3 4 508 3 6292
regulation of primary metabolic process 2.0368E-3 4 514 3 6292
regulation of cellular metabolic process 2.3038E-3 4 536 3 6292
regulation of metabolic process 2.4454E-3 4 547 3 6292
transcription 2.5116E-3 4 552 3 6292
chromosome organization 2.5518E-3 4 555 3 6292
cellular component biogenesis 4.9063E-3 4 694 3 6292
DNA repair 5.3374E-3 4 192 2 6292
regulation of cellular process 7.309E-3 4 796 3 6292
response to DNA damage stimulus 7.9954E-3 4 236 2 6292
regulation of biological process 8.0789E-3 4 824 3 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

transcription regulator activity 5.9551E-4 4 339 3 6292
oxidoreductase activity, oxidizing metal ions, oxygen as acceptor 1.2712E-3 4 2 1 6292
ferroxidase activity 1.2712E-3 4 2 1 6292
oxidoreductase activity, oxidizing metal ions 7.6087E-3 4 12 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle