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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 6 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ESCRT II complex 4.8197E-10 6 3 3 6292
endosomal part 8.4748E-7 6 23 3 6292
endosome membrane 8.4748E-7 6 23 3 6292
endosome 6.2526E-5 6 94 3 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of transcription by carbon catabolites 1.6845E-8 6 7 3 6292
negative regulation of transcription by glucose 1.6845E-8 6 7 3 6292
negative regulation of transcription from RNA polymerase II promoter by carbon catabolites 1.6845E-8 6 7 3 6292
negative regulation of transcription from RNA polymerase II promoter by glucose 1.6845E-8 6 7 3 6292
regulation of transcription from RNA polymerase II promoter by carbon catabolites 1.6845E-8 6 7 3 6292
regulation of transcription from RNA polymerase II promoter by glucose 1.6845E-8 6 7 3 6292
regulation of transcription by glucose 2.6942E-8 6 8 3 6292
cellular response to nutrient 1.3735E-7 6 13 3 6292
regulation of transcription by carbon catabolites 1.3735E-7 6 13 3 6292
response to nutrient 2.6865E-7 6 16 3 6292
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 3.9118E-7 6 18 3 6292
cellular response to external stimulus 3.1185E-6 6 35 3 6292
cellular response to extracellular stimulus 3.1185E-6 6 35 3 6292
cellular response to nutrient levels 3.1185E-6 6 35 3 6292
response to extracellular stimulus 4.0152E-6 6 38 3 6292
response to nutrient levels 4.0152E-6 6 38 3 6292
response to external stimulus 4.0152E-6 6 38 3 6292
cell communication 8.7346E-6 6 49 3 6292
negative regulation of transcription from RNA polymerase II promoter 1.6159E-5 6 60 3 6292
regulation of transcription from RNA polymerase II promoter 2.3796E-5 6 228 4 6292
protein targeting to vacuole 2.4661E-5 6 69 3 6292
anatomical structure homeostasis 5.8338E-5 6 286 4 6292
telomere organization 5.8338E-5 6 286 4 6292
telomere maintenance 5.8338E-5 6 286 4 6292
cellular response to chemical stimulus 9.2151E-5 6 107 3 6292
transcription from RNA polymerase II promoter 1.0874E-4 6 335 4 6292
vacuolar transport 1.143E-4 6 115 3 6292
regulation of transcription, DNA-dependent 1.4112E-4 6 358 4 6292
regulation of RNA metabolic process 1.4901E-4 6 363 4 6292
regulation of transcription 1.8573E-4 6 384 4 6292
homeostatic process 2.354E-4 6 408 4 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.5156E-4 6 415 4 6292
regulation of nitrogen compound metabolic process 2.5394E-4 6 416 4 6292
modification-dependent protein catabolic process 2.8306E-4 6 156 3 6292
ubiquitin-dependent protein catabolic process 2.8306E-4 6 156 3 6292
negative regulation of transcription, DNA-dependent 2.8847E-4 6 157 3 6292
negative regulation of RNA metabolic process 2.9395E-4 6 158 3 6292
proteolysis involved in cellular protein catabolic process 2.9949E-4 6 159 3 6292
modification-dependent macromolecule catabolic process 3.2824E-4 6 164 3 6292
negative regulation of transcription 3.2824E-4 6 164 3 6292
negative regulation of gene expression 3.2824E-4 6 164 3 6292
regulation of gene expression 3.3024E-4 6 445 4 6292
regulation of macromolecule biosynthetic process 3.6316E-4 6 456 4 6292
cellular protein catabolic process 3.7142E-4 6 171 3 6292
negative regulation of macromolecule biosynthetic process 3.9768E-4 6 175 3 6292
regulation of cellular biosynthetic process 4.1527E-4 6 472 4 6292
regulation of biosynthetic process 4.187E-4 6 473 4 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3217E-4 6 180 3 6292
negative regulation of nitrogen compound metabolic process 4.3217E-4 6 180 3 6292
regulation of macromolecule metabolic process 4.7266E-4 6 488 4 6292
proteolysis 4.9131E-4 6 188 3 6292
negative regulation of biosynthetic process 4.9905E-4 6 189 3 6292
negative regulation of cellular biosynthetic process 4.9905E-4 6 189 3 6292
protein catabolic process 4.9905E-4 6 189 3 6292
negative regulation of macromolecule metabolic process 5.2276E-4 6 192 3 6292
transcription, DNA-dependent 5.3154E-4 6 503 4 6292
RNA biosynthetic process 5.5231E-4 6 508 4 6292
regulation of primary metabolic process 5.7801E-4 6 514 4 6292
negative regulation of cellular metabolic process 6.7096E-4 6 209 3 6292
regulation of cellular metabolic process 6.7976E-4 6 536 4 6292
negative regulation of metabolic process 6.8043E-4 6 210 3 6292
regulation of metabolic process 7.3526E-4 6 547 4 6292
regulation of biological quality 7.5624E-4 6 551 4 6292
transcription 7.6155E-4 6 552 4 6292
chromosome organization 7.7766E-4 6 555 4 6292
protein targeting 9.4628E-4 6 235 3 6292
DNA metabolic process 9.5262E-4 6 585 4 6292
negative regulation of cellular process 1.1339E-3 6 250 3 6292
negative regulation of biological process 1.1741E-3 6 253 3 6292
intracellular protein transport 1.2014E-3 6 255 3 6292
cellular macromolecule catabolic process 1.344E-3 6 265 3 6292
protein transport 1.404E-3 6 269 3 6292
establishment of protein localization 1.4346E-3 6 271 3 6292
cellular protein localization 1.4813E-3 6 274 3 6292
cellular macromolecule localization 1.644E-3 6 284 3 6292
macromolecule catabolic process 1.8178E-3 6 294 3 6292
regulation of transcription involved in S-phase of mitotic cell cycle 1.9064E-3 6 2 1 6292
protein localization 1.984E-3 6 303 3 6292
regulation of cellular process 3.0881E-3 6 796 4 6292
regulation of biological process 3.5191E-3 6 824 4 6292
cellular response to stimulus 3.7823E-3 6 379 3 6292
response to chemical stimulus 3.8687E-3 6 382 3 6292
macromolecule localization 4.3197E-3 6 397 3 6292
cellular catabolic process 4.9029E-3 6 415 3 6292
RNA metabolic process 6.0989E-3 6 954 4 6292
catabolic process 8.1296E-3 6 496 3 6292
S phase 9.5019E-3 6 10 1 6292
S phase of mitotic cell cycle 9.5019E-3 6 10 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulator of G-protein signaling activity 9.5359E-4 6 1 1 6292
alcohol dehydrogenase (NADP+) activity 2.8585E-3 6 3 1 6292
aldo-keto reductase activity 8.5551E-3 6 9 1 6292

YRC Informatics Platform - Version 3.0
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