YRC Public Data Repository - Protein Complex GO Analysis

Complex Overview

From Publication:	Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes:	Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size:	13 proteins

Complex Member Proteins

Protein	GO Cellular Component	GO Biological Process	GO Molecular Function
FUN12	mitochondrion	translational initiation	translation initiation factor activity GTPase activity
RPL15A	ribonucleoprotein complex cytoplasm cytosolic large ribosomal subunit ribosome intracellular	translation	RNA binding structural constituent of ribosome
RPL20B		ribosome biogenesis translation	structural constituent of ribosome
RPL4B	cytoplasm	translation	structural constituent of ribosome
RPS11A, RPS11B	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm ribosome 90S preribosome intracellular	regulation of translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosomal small subunit assembly translation	RNA binding structural constituent of ribosome rRNA binding
RPS1A	ribonucleoprotein complex cytoplasm cytosolic small ribosomal subunit ribosome 90S preribosome intracellular	translation	structural constituent of ribosome
RPS1B	ribonucleoprotein complex cytoplasm cytosolic small ribosomal subunit ribosome 90S preribosome intracellular	translation	structural constituent of ribosome
RPS3	preribosome, small subunit precursor	response to DNA damage stimulus translation	structural constituent of ribosome
RPS4B, RPS4A	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm ribosome 90S preribosome intracellular	regulation of translation translation	RNA binding structural constituent of ribosome rRNA binding
RPS6A, RPS6B	small-subunit processome nucleus ribonucleoprotein complex cytoplasm cytosolic small ribosomal subunit ribosome nucleolus 90S preribosome intracellular	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis rRNA processing translation	structural constituent of ribosome
RPS7A	small nucleolar ribonucleoprotein complex	translation	structural constituent of ribosome
RPS8B, RPS8A	ribonucleoprotein complex cytosolic small ribosomal subunit cytoplasm 90S preribosome ribosome intracellular	regulation of translation maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) translation	structural constituent of ribosome
UTP22	nucleus nuclear outer membrane nucleolus small nucleolar ribonucleoprotein complex	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) ribosome biogenesis rRNA processing	snoRNA binding

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
preribosome	1.169E-13	13	34	7	6292
90S preribosome	2.4444E-13	13	17	6	6292
cytosolic small ribosomal subunit	5.3441E-11	13	38	6	6292
cytosolic ribosome	3.5324E-10	13	101	7	6292
cytosolic part	1.3515E-9	13	122	7	6292
ribonucleoprotein complex	2.7819E-9	13	514	10	6292
small ribosomal subunit	3.1863E-9	13	73	6	6292
ribosomal subunit	2.3258E-8	13	183	7	6292
cytosol	4.8191E-7	13	284	7	6292
ribosome	5.5583E-7	13	290	7	6292
macromolecular complex	1.7639E-4	13	1635	10	6292
non-membrane-bounded organelle	1.7806E-4	13	959	8	6292
intracellular non-membrane-bounded organelle	1.7806E-4	13	959	8	6292
small nucleolar ribonucleoprotein complex	9.2843E-3	13	72	2	6292

Biological Process Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
translation	2.1597E-14	13	376	12	6292
gene expression	1.0037E-9	13	1283	13	6292
cellular protein metabolic process	6.3767E-9	13	1074	12	6292
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	7.7554E-9	13	13	4	6292
protein metabolic process	1.2412E-8	13	1136	12	6292
cellular macromolecule biosynthetic process	2.0887E-8	13	1187	12	6292
macromolecule biosynthetic process	2.1308E-8	13	1189	12	6292
cellular biosynthetic process	5.5313E-7	13	1567	12	6292
biosynthetic process	7.1688E-7	13	1602	12	6292
cellular macromolecule metabolic process	1.8698E-6	13	2285	13	6292
macromolecule metabolic process	2.6802E-6	13	2349	13	6292
maturation of SSU-rRNA	4.6825E-6	13	59	4	6292
primary metabolic process	4.1002E-5	13	2896	13	6292
cellular metabolic process	7.4867E-5	13	3033	13	6292
rRNA processing	1.0135E-4	13	128	4	6292
metabolic process	1.2617E-4	13	3157	13	6292
rRNA metabolic process	1.3204E-4	13	137	4	6292
regulation of translation	1.8907E-4	13	57	3	6292
posttranscriptional regulation of gene expression	2.3144E-4	13	61	3	6292
regulation of cellular protein metabolic process	3.1959E-4	13	68	3	6292
regulation of protein metabolic process	4.1043E-4	13	74	3	6292
ribosome biogenesis	4.3563E-4	13	346	5	6292
ribonucleoprotein complex biogenesis	6.2467E-4	13	374	5	6292
ncRNA processing	7.4339E-4	13	215	4	6292
ncRNA metabolic process	1.4518E-3	13	257	4	6292
RNA processing	6.0507E-3	13	380	4	6292
cellular component biogenesis	9.7186E-3	13	694	5	6292

Molecular Function Analysis

Only showing terms with a p-value less than or equal to 0.01.

GO Term	P-value	A	B	I	T
structural constituent of ribosome	3.618E-15	13	212	11	6292
structural molecule activity	6.7238E-13	13	339	11	6292
rRNA binding	4.6527E-4	13	16	2	6292
RNA binding	5.3427E-3	13	367	4	6292
nucleic acid binding	8.1613E-3	13	666	5	6292

View Protein Complex Details

Complex Overview

Complex Member Proteins

Cellular Component Analysis

Biological Process Analysis

Molecular Function Analysis