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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.558390905347]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
GPB1
  • cytoplasm
  • plasma membrane
    		•
  • filamentous growth
  • negative regulation of Ras protein signal transduction
  • signal transduction
  • invasive growth in response to glucose limitation
  • negative regulation of phosphorylation
    		•
  • GTPase activating protein binding
  • protein kinase inhibitor activity
  • signal transducer activity
    		•
    GPB2
  • cytoplasm
  • mitochondrion
  • plasma membrane
    		•
  • ascospore formation
  • filamentous growth
  • negative regulation of Ras protein signal transduction
  • signal transduction
  • telomere maintenance
  • invasive growth in response to glucose limitation
  • positive regulation of transcription from RNA polymerase II promoter
  • negative regulation of phosphorylation
    		•
  • GTPase activating protein binding
  • protein kinase inhibitor activity
  • signal transducer activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    plasma membrane 1.8077E-3 2 268 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    negative regulation of phosphate metabolic process 5.0527E-7 2 5 2 6292
    negative regulation of phosphorylation 5.0527E-7 2 5 2 6292
    negative regulation of phosphorus metabolic process 5.0527E-7 2 5 2 6292
    regulation of Ras protein signal transduction 7.579E-7 2 6 2 6292
    negative regulation of Ras protein signal transduction 7.579E-7 2 6 2 6292
    negative regulation of cell communication 7.579E-7 2 6 2 6292
    negative regulation of small GTPase mediated signal transduction 7.579E-7 2 6 2 6292
    regulation of small GTPase mediated signal transduction 7.579E-7 2 6 2 6292
    negative regulation of signaling pathway 7.579E-7 2 6 2 6292
    regulation of cell communication 4.5979E-6 2 14 2 6292
    regulation of signaling pathway 1.9099E-5 2 28 2 6292
    regulation of phosphorylation 2.3495E-5 2 31 2 6292
    regulation of phosphate metabolic process 3.552E-5 2 38 2 6292
    regulation of phosphorus metabolic process 3.552E-5 2 38 2 6292
    Ras protein signal transduction 4.1432E-5 2 41 2 6292
    invasive growth in response to glucose limitation 5.4619E-5 2 47 2 6292
    cell communication 5.9419E-5 2 49 2 6292
    small GTPase mediated signal transduction 1.0186E-4 2 64 2 6292
    filamentous growth of a population of unicellular organisms 2.0236E-4 2 90 2 6292
    growth of unicellular organism as a thread of attached cells 2.0236E-4 2 90 2 6292
    filamentous growth 2.8118E-4 2 106 2 6292
    intracellular signal transduction 3.312E-4 2 115 2 6292
    intracellular signaling pathway 5.2022E-4 2 144 2 6292
    growth 5.275E-4 2 145 2 6292
    phosphorylation 8.0494E-4 2 179 2 6292
    signaling pathway 8.5067E-4 2 184 2 6292
    negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
    negative regulation of metabolic process 1.1088E-3 2 210 2 6292
    signal transduction 1.1516E-3 2 214 2 6292
    signal transmission 1.1841E-3 2 217 2 6292
    signaling process 1.1841E-3 2 217 2 6292
    phosphorus metabolic process 1.3191E-3 2 229 2 6292
    phosphate metabolic process 1.3191E-3 2 229 2 6292
    negative regulation of cellular process 1.5726E-3 2 250 2 6292
    signaling 1.598E-3 2 252 2 6292
    negative regulation of biological process 1.6107E-3 2 253 2 6292
    regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
    regulation of metabolic process 7.5452E-3 2 547 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    GTPase activating protein binding 1.5158E-7 2 3 2 6292
    protein kinase inhibitor activity 2.779E-6 2 11 2 6292
    kinase inhibitor activity 2.779E-6 2 11 2 6292
    enzyme inhibitor activity 1.7735E-5 2 27 2 6292
    protein kinase regulator activity 5.2295E-5 2 46 2 6292
    kinase regulator activity 5.9419E-5 2 49 2 6292
    molecular transducer activity 1.5966E-4 2 80 2 6292
    signal transducer activity 1.5966E-4 2 80 2 6292
    enzyme regulator activity 1.0773E-3 2 207 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
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