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A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors. The series of molecular events whereby information is sent from one location to another within a living organism or between living organisms. Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals. The series of molecular events whereby information is sent from one location to another within a cell. The process whereby a signal is released and/or conveyed from one location to another. The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1. A series of reactions, mediated by the intracellular phosphoinositide 3-kinase (PI3K). PI3K cascades lie downstream of many cell surface receptor linked signaling pathways and regulate numerous cellular functions. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound. The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. The process whereby an activated receptor conveys information down the signaling pathway, resulting in a change in the function or state of a cell. The process whereby a signal is passed on from a receptor at the cell surface to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. A series of molecular signals in which an ion or small molecule is formed or released into the cytosol, thereby helping relay the signal within the cell.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: intracellular signal transduction
Acc: GO:0035556
Aspect: Biological Process
Desc: The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
Synonyms:
  • signal transduction via intracellular signaling cascade
  • intracellular signaling chain
  • intracellular signaling cascade
Proteins in PDR annotated with:
   This term: 0
   Term or descendants: 3800 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0035556 - intracellular signal transduction (interactive image map)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle