Protein Overview: PHO5

General Information:
Name(s) found:	PHO5 / YBR093C [SGD]
Description(s) found: Found 30 descriptions. SHOW ALL	Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2 [SGD]
Organism:	Saccharomyces cerevisiae
Length:	467 amino acids
Gene Ontology:
Cellular Component:	fungal-type cell wall [IDA] cell wall-bounded periplasmic space [NAS]
Biological Process:	regulation of cell size [IMP] cellular response to phosphate starvation [IEP][IMP][TAS] phosphate metabolic process [IMP][TAS]
Molecular Function:	nucleoside-triphosphatase activity [IGI][IMP] nucleoside-triphosphate diphosphatase activity [IGI][IMP] acid phosphatase activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFKSVVYSIL AASLANAGTI PLGKLADVDK IGTQKDIFPF LGGAGPYYSF PGDYGISRDL  60
   61 PEGCEMKQLQ MVGRHGERYP TVSLAKTIKS TWYKLSNYTR QFNGSLSFLN DDYEFFIRDD 120
  121 DDLEMETTFA NSDDVLNPYT GEMNAKRHAR DFLAQYGYMV ENQTSFAVFT SNSKRCHDTA 180
  181 QYFIDGLGDQ FNITLQTVSE AESAGANTLS ACNSCPAWDY DANDDIVNEY DTTYLDDIAK 240
  241 RLNKENKGLN LTSTDASTLF SWCAFEVNAK GYSDVCDIFT KDELVHYSYY QDLHTYYHEG 300
  301 PGYDIIKSVG SNLFNASVKL LKQSEIQDQK VWLSFTHDTD ILNFLTTAGI IDDKNNLTAE 360
  361 YVPFMGNTFH RSWYVPQGAR VYTEKFQCSN DTYVRYVIND AVVPIETCST GPGFSCEIND 420
  421 FYDYAEKRVA GTDFLKVCNV SSVSNSTELT FYWDWNTTHY NASLLRQ

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		BUD5 IRC7 PHO11 PHO5
View Details	Qiu et al. (2008)		ASP3-4, ASP3-1, ... PHO3 PHO5

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	SOG2	PHO5	2	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	PHO5	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..44] [77..141] [230..288]	PSI-BLAST	693.36704	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)
2	View Details	[45..76] [142..229] [289..467]	PSI-BLAST	693.36704	Phytase (myo-inositol-hexakisphosphate-3-phosphohydrolase)

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

[View Details]

Source: Reynolds et al. 2008. Manuscript submitted

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2