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Protein Overview: BRPF1

General Information:
Name(s) found: BRPF1 [HGNC (HUGO)]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • bromodomain and PHD finger containing, 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 1214 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDNP PPPQQTPLRK  60
   61 HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE VDLHGRVHRI SIFDNLDVVS 120
  121 EDEEAPEEAP ENGSNKENTE TPAATPKSGK HKNKEKRKDS NHHHHHNVSA STTPKLPEVV 180
  181 YRELEQDTPD APPRPTSYYR YIEKSAEELD EEVEYDMDEE DYIWLDIMNE RRKTEGVSPI 240
  241 PQEIFEYLMD RLEKESYFES HNKGDPNALV DEDAVCCICN DGECQNSNVI LFCDMCNLAV 300
  301 HQECYGVPYI PEGQWLCRRC LQSPSRAVDC ALCPNKGGAF KQTDDGRWAH VVCALWIPEV 360
  361 CFANTVFLEP IDSIEHIPPA RWKLTCYICK QRGSGACIQC HKANCYTAFH VTCAQQAGLY 420
  421 MKMEPVRETG ANGTSFSVRK TAYCDIHTPP GSARRLPALS HSEGEEDEDE EEDEGKGWSS 480
  481 EKVKKAKAKS RIKMKKARKI LAEKRAAAPV VSVPCIPPHR LSKITNRLTI QRKSQFMQRL 540
  541 HSYWTLKRQS RNGVPLLRRL QTHLQSQRNC DQVGRDSEDK NWALKEQLKS WQRLRHDLER 600
  601 ARLLVELIRK REKLKRETIK VQQIAMEMQL TPFLILLRKT LEQLQEKDTG NIFSEPVPLS 660
  661 EVPDYLDHIK KPMDFFTMKQ NLEAYRYLNF DDFEEDFNLI VSNCLKYNAK DTIFYRAAVR 720
  721 LREQGGAVLR QARRQAEKMG IDFETGMHIP HSLAGDEATH HTEDAAEEER LVLLENQKHL 780
  781 PVEEQLKLLL ERLDEVNASK QSVGRSRRAK MIKKEMTALR RKLAHQRETG RDGPERHGPS 840
  841 SRGSLTPHPA ACDKDGQTDS AAEESSSQET SKGLGPNMSS TPAHEVGRRT SVLFSKKNPK 900
  901 TAGPPKRPGR PPKNRESQMT PSHGGSPVGP PQLPIMSSLR QRKRGRSPRP SSSSDSDSDK 960
  961 STEDPPMDLP ANGFSGGNQP VKKSFLVYRN DCSLPRSSSD SESSSSSSSS AASDRTSTTP1020
 1021 SKQGRGKPSF SRGTFPEDSS EDTSGTENEA YSVGTGRGVG HSMVRKSLGR GAGWLSEDED1080
 1081 SPLDALDLVW AKCRGYPSYP ALIIDPKMPR EGMFHHGVPI PVPPLEVLKL GEQMTQEARE1140
 1141 HLYLVLFFDN KRTWQWLPRT KLVPLGVNQD LDKEKMLEGR KSNIRKSVQI AYHRALQHRS1200
 1201 KVQGEQSSET SDSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..116] FFAS03 2.02 No description for 2ghfA was found.
    2 View Details [117..260] deduced N/A No confident structure predictions are available.
    3 View Details [261..454] PSI-BLAST 8.69897 No description for 2ysmA was found.
    4 View Details [455..624] deduced N/A No confident structure predictions are available.
    5 View Details [625..752] PSI-BLAST 25.045757 No description for 2d9eA was found.
    6 View Details [753..873] deduced N/A No confident structure predictions are available.
    7 View Details [874..1076] MSA 3.324995 View MSA. No confident structure predictions are available.
    8 View Details [1077..1214] PSI-BLAST 19.522879 No description for 2gfuA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.56065593409893 bayes_pls_golite062009
  • DNA binding
    		•  2.12670364830465 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.03166503403228 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.89798946190385 bayes_pls_golite062009
  • transcription factor activity
    		•  1.25050641170057 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.983792216045634 bayes_pls_golite062009
  • protein binding
    		•  0.975412203442928 bayes_pls_golite062009
  • transcription activator activity
    		•  0.682903516955242 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.343953984757786 bayes_pls_golite062009
  • chromatin binding
    		•  0.187378781886193 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.0838352585191493 bayes_pls_golite062009
  • transcription factor binding
    		•  0.059503646600688 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle