Protein Overview: GRIA1_RAT

General Information:
Name(s) found:	GRIA1_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|97536283\|sp\|P19490.2\|GRIA1_RAT RecName: Full=Glutamate receptor 1; Short=GluR-1; AltName: Full=GluR-A; AltName: Full=GluR-K1; AltName: Full=Glutamate receptor ionotropic, AMPA 1; AltName: Full=AMPA-selective glutamate receptor 1; Flags: Precursor [NCBI NR] gi\|84373698\|gb\|AAA41243.2\| glutamate receptor GluR-A [Rattus norvegicus] [NCBI NR] gi\|3402257\|emb\|CAA35050.1\| glutamate receptor, AMPA subtype, GluR1 [Rattus norvegicus] [NCBI NR] gi\|29789269\|ref\|NP_113796.1\| glutamate receptor, ionotropic, AMPA 1 [Rattus norvegicus] [NCBI NR] gi\|149052676\|gb\|EDM04493.1\| glutamate receptor, ionotropic, AMPA1 (alpha 1), isoform CRA_a [Rattus norvegicus] [NCBI NR] Glutamate receptor 1 OS=Rattus norvegicus GN=Gria1 PE=1 SV=2 [Swiss-Prot] glutamate receptor, ionotropic, AMPA1 (alpha 1) [HMR_022704-rand.fasta] glutamate receptor, ionotropic, AMPA1 (alpha 1) [Rattus norvegicus]gi\|3402257\|emb\|CAA35050.1\| glutamate receptor, AMPA subtype, GluR1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform Flop of Glutamate receptor 1 precursor [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] glutamate receptor, ionotropic, AMPA1 (alpha 1) [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Glutamate receptor 1 precursor (GluR-1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1) (AMPA-selective glutamate receptor 1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor, ionotropic, AMPA1 (alpha 1), isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor GluR-A [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor, AMPA subtype, GluR1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] glutamate receptor, ionotropic, AMPA 1 [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Gria1 Isoform Flop of Glutamate receptor 1 [rat-ipi-250309-contam.fasta] Isoform Flop of Glutamate receptor 1 OS=Rattus norvegicus GN=Gria1 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	907 amino acids
Gene Ontology:
Cellular Component:	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex [UNKNOWN] postsynaptic density [IDA] synaptosome [IDA] endoplasmic reticulum [IEA] neuronal cell body [IDA] protein complex [IDA] synapse [IDA][IMP] ionotropic glutamate receptor complex [TAS] plasma membrane [UNKNOWN][IEA] membrane fraction [UNKNOWN] endoplasmic reticulum membrane [IEA] early endosome [IDA] postsynaptic membrane [IEA] dendritic shaft [IDA] dendritic spine [IDA] integral to membrane [IEA] cell junction [IEA] asymmetric synapse [IDA] endocytic vesicle membrane [UNKNOWN]
Biological Process:	ion transport [IEA] regulation of synaptic plasticity [IMP][NAS] positive regulation of synaptic transmission [IMP] response to lithium ion [IEP] regulation of synaptic transmission [IDA] receptor internalization [IDA] regulation of receptor recycling [IMP] regulation of action potential in neuron [IMP] synaptic transmission, glutamatergic [NAS]
Molecular Function:	ion channel activity [IEA] protein kinase binding [IPI] protein domain specific binding [IPI] protein binding [IPI] protein homodimerization activity [TAS] PDZ domain binding [IPI] small GTPase binding [IPI] receptor activity [IEA] ionotropic glutamate receptor activity [IEA] extracellular-glutamate-gated ion channel activity [IEA] myosin V binding [IPI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPYIFAFFCT GFLGAVVGAN FPNNIQIGGL FPNQQSQEHA AFRFALSQLT EPPKLLPQID  60
   61 IVNISDSFEM TYRFCSQFSK GVYAIFGFYE RRTVNMLTSF CGALHVCFIT PSFPVDTSNQ 120
  121 FVLQLRPELQ EALISIIDHY KWQTFVYIYD ADRGLSVLQR VLDTAAEKNW QVTAVNILTT 180
  181 TEEGYRMLFQ DLEKKKERLV VVDCESERLN AILGQIVKLE KNGIGYHYIL ANLGFMDIDL 240
  241 NKFKESGANV TGFQLVNYTD TIPARIMQQW RTSDSRDHTR VDWKRPKYTS ALTYDGVKVM 300
  301 AEAFQSLRRQ RIDISRRGNA GDCLANPAVP WGQGIDIQRA LQQVRFEGLT GNVQFNEKGR 360
  361 RTNYTLHVIE MKHDGIRKIG YWNEDDKFVP AATDAQAGGD NSSVQNRTYI VTTILEDPYV 420
  421 MLKKNANQFE GNDRYEGYCV ELAAEIAKHV GYSYRLEIVS DGKYGARDPD TKAWNGMVGE 480
  481 LVYGRADVAV APLTITLVRE EVIDFSKPFM SLGISIMIKK PQKSKPGVFS FLDPLAYEIW 540
  541 MCIVFAYIGV SVVLFLVSRF SPYEWHSEEF EEGRDQTTSD QSNEFGIFNS LWFSLGAFMQ 600
  601 QGCDISPRSL SGRIVGGVWW FFTLIIISSY TANLAAFLTV ERMVSPIESA EDLAKQTEIA 660
  661 YGTLEAGSTK EFFRRSKIAV FEKMWTYMKS AEPSVFVRTT EEGMIRVRKS KGKYAYLLES 720
  721 TMNEYIEQRK PCDTMKVGGN LDSKGYGIAT PKGSALRNPV NLAVLKLNEQ GLLDKLKNKW 780
  781 WYDKGECGSG GGDSKDKTSA LSLSNVAGVF YILIGGLGLA MLVALIEFCY KSRSESKRMK 840
  841 GFCLIPQQSI NEAIRTSTLP RNSGAGASGG GGSGENGRVV SQDFPKSMQS IPCMSHSSGM 900
  901 PLGATGL

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: GRIA1_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: