Protein Overview: DLDH_RAT

General Information:
Name(s) found:	DLDH_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81885266\|sp\|Q6P6R2.1\|DLDH_RAT RecName: Full=Dihydrolipoyl dehydrogenase, mitochondrial; AltName: Full=Dihydrolipoamide dehydrogenase; Flags: Precursor [NCBI NR] gi\|40786469\|ref\|NP_955417.1\| dihydrolipoamide dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|38303871\|gb\|AAH62069.1\| Dihydrolipoamide dehydrogenase [Rattus norvegicus] [NCBI NR] gi\|149051077\|gb\|EDM03250.1\| dihydrolipoamide dehydrogenase, isoform CRA_b [Rattus norvegicus] [NCBI NR] Dihydrolipoyl dehydrogenase, mitochondrial OS=Rattus norvegicus GN=Dld PE=1 SV=1 [Swiss-Prot] dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) [HMR_022704-rand.fasta] dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) [Rattus norvegicus]gi\|38303871\|gb\|AAH62069.1\| Dihydrolipoamide dehydrogenase (E3 component of pyruvat [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Dihydrolipoamide dehydrogenase [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] dihydrolipoamide dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dihydrolipoyl dehydrogenase, mitochondrial precursor (Dihydrolipoamide dehydrogenase) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] dihydrolipoamide dehydrogenase, isoform CRA_b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Dihydrolipoamide dehydrogenase [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 DIHYDROLIPOAMIDE DEHYDROGENASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex) [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Dld Dihydrolipoyl dehydrogenase, mitochondrial [rat-ipi-250309-contam.fasta] Dihydrolipoyl dehydrogenase, mitochondrial OS=Rattus norvegicus GN=Dld [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	509 amino acids
Gene Ontology:
Cellular Component:	pyruvate dehydrogenase complex [IDA] cytoplasm [IEA] mitochondrial matrix [IEA] oxoglutarate dehydrogenase complex [IDA] mitochondrion [UNKNOWN][IDA] flagellum [UNKNOWN][IEA] acrosomal matrix [UNKNOWN][IEA]
Biological Process:	acetyl-CoA biosynthetic process from pyruvate [IDA] mitochondrial electron transport, NADH to ubiquinone [UNKNOWN][IEA] cell redox homeostasis [IEA] aging [IEP] 2-oxoglutarate metabolic process [IDA] gastrulation [UNKNOWN][IEA] lipoate metabolic process [IDA] dihydrolipoamide metabolic process [IDA] regulation of membrane potential [UNKNOWN][IEA] sperm capacitation [UNKNOWN][IEA] proteolysis [UNKNOWN][IEA] oxidation reduction [IEA] regulation of acetyl-CoA biosynthetic process from pyruvate [UNKNOWN]
Molecular Function:	oxidoreductase activity [IEA] FAD binding [IDA][IEA] NAD or NADH binding [IDA] electron carrier activity [IEA] lipoamide binding [IDA] dihydrolipoyl dehydrogenase activity [UNKNOWN][IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSWSRVYCS LAKKGHFNRL SHGLQGASSV PLRTYSDQPI DADVTVIGSG PGGYVAAIKA  60
   61 AQLGFKTVCI EKNETLGGTC LNVGCIPSKA LLNNSHYYHL AHGKDFASRG IEIPEVRLNL 120
  121 EKMMEQKRSA VKALTGGIAH LFKQNKVVHV NGFGKITGKN QVTATTADGS TQVIGTKNIL 180
  181 IATGSEVTPF PGITIDEDTI VSSTGALSLK KVPEKLVVIG AGVIGVELGS VWQRLGADVT 240
  241 AVEFLGHVGG IGIDMEISKN FQRILQKQGF KFKLNTKVTG ATKKSDGKID VSVEAASGGK 300
  301 AEVITCDVLL VCIGRRPFTQ NLGLEELGIE LDPKGRIPVN TRFQTKIPNI FAIGDVVAGP 360
  361 MLAHKAEDEG IICVEGMAGG AVHIDYNCVP SVIYTHPEVA WVGKSEEQLK EEGVEFKVGK 420
  421 FPFAANSRAK TNADTDGMVK ILGHKSTDRI LGAHILGPGA GEMVNEAALA LEYGASCEDV 480
  481 ARVCHAHPTL SEAFREANLA ASFGKPINF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.97

Protein Overview: DLDH_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: