Protein Overview: SCN9A_RAT

General Information:
Name(s) found:	SCN9A_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|55976160\|sp\|O08562.1\|SCN9A_RAT RecName: Full=Sodium channel protein type 9 subunit alpha; AltName: Full=Sodium channel protein type IX subunit alpha; AltName: Full=Voltage-gated sodium channel subunit alpha Nav1.7; AltName: Full=Peripheral sodium chann [NCBI NR] gi\|2501838\|gb\|AAB80701.1\| voltage-gated sodium channel [Rattus norvegicus] [NCBI NR] gi\|1906594\|gb\|AAB50403.1\| PN1 [Rattus norvegicus] [NCBI NR] gi\|18959222\|ref\|NP_579823.1\| sodium channel, voltage-gated, type IX, alpha [Rattus norvegicus] [NCBI NR] Sodium channel protein type 9 subunit alpha OS=Rattus norvegicus GN=Scn9a PE=1 SV=1 [Swiss-Prot] sodium channel 25; sodium channel, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha polypeptide; sodium channel type IX alpha polypeptide; sodium channel voltage-gated type IX alpha polypeptide [HMR_022704-rand.fasta] sodium channel 25 [Rattus norvegicus]gi\|2501838\|gb\|AAB80701.1\| voltage-gated sodium channel [Rattus norvegicus]gi\|1906594\|gb\|AAB50403.1\| PN1 [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Sodium channel protein type 9 alpha subunit [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Sodium channel protein type IX alpha subunit [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta] (NM_133289) sodium channel 25; sodium channel, type IX, alpha polypeptide; sodium channel, voltage-gated, type IX, alpha polypeptide [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] Sodium channel protein type 9 subunit alpha (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7) (Peripheral sodium channel 1) (PN1) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sodium channel, voltage-gated, type IX, alpha [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] voltage-gated sodium channel [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] PN1 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] sodium channel 25 [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Scn9a Sodium channel protein type 9 subunit alpha [rat-ipi-250309-contam.fasta] Sodium channel protein type 9 subunit alpha OS=Rattus norvegicus GN=Scn9a [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1984 amino acids
Gene Ontology:
Cellular Component:	membrane [IEA] integral to membrane [IEA] voltage-gated sodium channel complex [IDA]
Biological Process:	sodium ion transport [IEA] ion transport [IEA] inflammatory response [UNKNOWN][IEA] transmembrane transport [IEA] post-embryonic development [UNKNOWN][IEA] behavioral response to pain [UNKNOWN][IEA] rhythmic excitation [NAS] regulation of action potential in neuron [IDA]
Molecular Function:	voltage-gated ion channel activity [IEA] sodium ion binding [IDA] voltage-gated sodium channel activity [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMLPPPGPQ SFVHFTKQSL ALIEQRISEE KAKEHKDEKK DDEEEGPKPS SDLEAGKQLP  60
   61 FIYGDIPPGM VSEPLEDLDP YYADKKTFIV LNKGKAIFRF NATPALYMLS PFSPLRRISI 120
  121 KILVHSLFSM LIMCTILTNC IFMTLSNPPE WTKNVEYTFT GIYTFESLIK ILARGFCVGE 180
  181 FTFLRDPWNW LDFVVIVFAY LTEFVNLGNV SALRTFRVLR ALKTISVIPG LKTIVGALIQ 240
  241 SVKKLSDVMI LTVFCLSVFA LIGLQLFMGN LKHKCFRKEL EENETLESIM NTAESEEELK 300
  301 KYFYYLEGSK DALLCGFSTD SGQCPEGYIC VKAGRNPDYG YTSFDTFSWA FLALFRLMTQ 360
  361 DYWENLYQQT LRAAGKTYMI FFVVVIFLGS FYLINLILAV VAMAYEEQNQ ANIEEAKQKE 420
  421 LEFQQMLDRL KKEQEEAEAI AAAAAEFTSI GRSRIMGLSE SSSETSRLSS KSAKERRNRR 480
  481 KKKKQKMSSG EEKGDDEKLS KSGSEESIRK KSFHLGVEGH HRTREKRLST PNQSPLSIRG 540
  541 SLFSARRSSR TSLFSFKGRG RDLGSETEFA DDEHSIFGDN ESRRGSLFVP HRPRERRSSN 600
  601 ISQASRSPPV LPVNGKMHSA VDCNGVVSLV DGPSALMLPN GQLLPEVIID KATSDDSGTT 660
  661 NQMRKKRLSS SYFLSEDMLN DPHLRQRAMS RASILTNTVE ELEESRQKCP PWWYRFAHTF 720
  721 LIWNCSPYWI KFKKLIYFIV MDPFVDLAIT ICIVLNTLFM AMEHHPMTEE FKNVLAVGNL 780
  781 IFTGIFAAEM VLKLIAMDPY EYFQVGWNIF DSLIVTLSLI ELFLADVEGL SVLRSFRLLR 840
  841 VFKLAKSWPT LNMLIKIIGN SVGALGNLTL VLAIIVFIFA VVGMQLFGKS YKECVCKINV 900
  901 DCKLPRWHMN DFFHSFLIVF RVLCGEWIET MWDCMEVAGQ TMCLIVYMMV MVIGNLVVLN 960
  961 LFLALLLSSF SSDNLTAIEE DTDANNLQIA VARIKRGINY VKQTLREFIL KSFSKKPKGS1020
 1021 KDTKRTADPN NKKENYISNR TLAEMSKDHN FLKEKDRISG YGSSLDKSFM DENDYQSFIH1080
 1081 NPSLTVTVPI APGESDLEIM NTEELSSDSD SDYSKEKRNR SSSSECSTVD NPLPGEEEAE1140
 1141 AEPVNADEPE ACFTDGCVRR FPCCQVNVDS GKGKVWWTIR KTCYRIVEHS WFESFIVLMI1200
 1201 LLSSGALAFE DIYIEKKKTI KIILEYADKI FTYIFILEML LKWVAYGYKT YFTNAWCWLD1260
 1261 FLIVDVSLVT LVANTLGYSD LGPIKSLRTL RALRPLRALS RFEGMRVVVN ALIGAIPSIM1320
 1321 NVLLVCLIFW LIFSIMGVNL FAGKFYECVN TTDGSRFPTS QVANRSECFA LMNVSGNVRW1380
 1381 KNLKVNFDNV GLGYLSLLQV ATFKGWMDIM YAAVDSVNVN EQPKYEYSLY MYIYFVIFII1440
 1441 FGSFFTLNLF IGVIIDNFNQ QKKKLGGQDI FMTEEQKKYY NAMKKLGSKK PQKPIPRPGN1500
 1501 KFQGCIFDLV TNQAFDITIM VLICLNMVTM MVEKEGQTEY MDYVLHWINM VFIILFTGEC1560
 1561 VLKLISLRHY YFTVGWNIFD FVVVILSIVG MFLAEMIEKY FVSPTLFRVI RLARIGRILR1620
 1621 LIKGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG MSNFAYVKKE AGINDMFNFE1680
 1681 TFGNSMICLF QITTSAGWDG LLAPILNSAP PDCDPKKVHP GSSVEGDCGN PSVGIFYFVS1740
 1741 YIIISFLVVV NMYIAVILEN FSVATEESTE PLSEDDFEMF YEVWEKFDPD ATQFIEFCKL1800
 1801 SDFAAALDPP LLIAKPNKVQ LIAMDLPMVS GDRIHCLDIL FAFTKRVLGE GGEMDSLRSQ1860
 1861 MEERFMSANP SKVSYEPITT TLKRKQEEVS ATIIQRAYRR YRLRQHVKNI SSIYIKDGDR1920
 1921 DDDLPNKEDT VFDNVNENSS PEKTDVTAST ISPPSYDSVT KPDQEKYETD KTEKEDKEKD1980
 1981 ESRK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SCN9A_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: