Protein Overview: PKHG5_RAT

General Information:
Name(s) found:	PKHG5_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81911547\|sp\|Q6RFZ7.1\|PKHG5_RAT RecName: Full=Pleckstrin homology domain-containing family G member 5; AltName: Full=Neuronal RhoA GEF protein; AltName: Full=Transcript highly enriched in cortex and hippocampus [NCBI NR] gi\|41152499\|ref\|NP_958429.1\| neuronal RhoA GEF protein [Rattus norvegicus] [NCBI NR] gi\|40786869\|gb\|AAR89949.1\| neuronal RhoA GEF protein [Rattus norvegicus] [NCBI NR] Pleckstrin homology domain-containing family G member 5 OS=Rattus norvegicus GN=Plekhg5 PE=1 SV=1 [Swiss-Prot] neuronal RhoA GEF protein [HMR_022704-rand.fasta] neuronal RhoA GEF protein [Rattus norvegicus]gi\|40786869\|gb\|AAR89949.1\| neuronal RhoA GEF protein [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Neuronal RhoA GEF protein [EBI-IPI_rat_3.08_07-12-2005_origrev_con.fasta] Pleckstrin homology domain-containing family G member 5 (Neuronal RhoA GEF protein) (Transcript highly enriched in cortex and hippocampus) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] neuronal RhoA GEF protein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 NEURONAL RHOA GEF PROTEIN [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Plekhg5 Pleckstrin homology domain-containing family G member 5 [rat-ipi-250309-contam.fasta] pleckstrin homology domain-containing family G member 5 [Rattus norvegicus] [NCBI-RefSeq_Human_na_04-23-2010_reversed.fasta] Pleckstrin homology domain-containing family G member 5 OS=Rattus norvegicus GN=Plekhg5 [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	1039 amino acids
Gene Ontology:
Cellular Component:	perinuclear region of cytoplasm [IEA] cytoplasm [UNKNOWN][IEA] cytosol [UNKNOWN] intracellular [IEA] plasma membrane [UNKNOWN]
Biological Process:	regulation of Rho protein signal transduction [IEA] apoptosis [UNKNOWN] positive regulation of I-kappaB kinase/NF-kappaB cascade [UNKNOWN] endothelial cell migration [UNKNOWN] induction of apoptosis by extracellular signals [UNKNOWN]
Molecular Function:	protein binding [UNKNOWN] guanyl-nucleotide exchange factor activity [UNKNOWN] Rho guanyl-nucleotide exchange factor activity [UNKNOWN][IEA] signal transducer activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDKGRAAKVC HHADCQQLHH RGPLNLCEIC DSKFHNTTHY DGHVRFDLPP QGSVLARNVS  60
   61 TRSCPPRTSP AGDLEEEDEG YTNGKGDRKS AGLKISKKKA RRRHTDDPSK ECFTLKFDLN 120
  121 VDIETEIVPA MKKKSLGEVL LPVFERKGIA LGKVDIYLDQ SNTPLSLTFE AYRFGGHYLR 180
  181 VKAKPGDEGK VEQGVKDSKS LSLPALRPSG AGTPVLERVD PQSRRESSLD ILAPGRRRKN 240
  241 MSEFLGDTSI PGQESPAPSS CSLPVGSSVG SSGSSESWKN RAASRFSGFF SSSPSTGAFG 300
  301 REVDKMEQLE SKLHAYSLFG LPRMPRRLRF DHDSWEEEED DEEEEDNSGL RLEDSWRELI 360
  361 DGHEKLTRRQ CHQQEAVWEL LHTEVSYIRK LRVITNLFLC CLLNLQESGL LCEVEAERLF 420
  421 SNIPELARLH RGLWSSVMVP VLEKARRTRA LLQPSDFLKG FKMFGSLFKP YIRYCMEEEG 480
  481 CMEYMRSLLR DNDLFRAYVT WAEKHQQCQR LKLSDMLAKP HQRLTKYPLL LKSVLRKTDE 540
  541 PRAKEAIITM ISSVERFIHH VNTCMRQRQE RQRLAGVVSR IDAYEVVEGS NDEVDKFLKE 600
  601 FLHLDLTAPM PGTSPEETRQ LLLEGSLRMK EGKDSKMDVY CFLFTDLLLV TKAVKKAERT 660
  661 KVIRPPLLVD KIVCRELRDP GSFLLIHLNE FHSAVGAYTF QASSQALCRS WVDTLYNAQN 720
  721 QLQQLRAQLL CAQEHPGTQH LQSLEEEEDE QEEEGEESGT SAASSPTILR KSSNSLDSEH 780
  781 CASDGSTETL AMVVVEPGET LSSPEFDRGP FSSQSDEASL SNTTSSITPT SELLPLGPVD 840
  841 GRSCSMDSAY GTLSPTSLQD FAAPHPVVEP VPVPQTLSPQ PSPRLRRRTP VQLLPRLPHL 900
  901 LKSKSEASLL QLLSGTTTSV SPPAPSRSLS ELCLITMAPG VRTQSSLQEG GPGWNCPGAC 960
  961 GPCQGPPLSE SENRPSHKAG GPADSARRKC REMPCGTVPR VQPEPSPGIS AQHRKLTLAQ1020
 1021 LYRIRTTLLL NSTLTASEV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PKHG5_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: