Protein Overview: SPRC_RAT

General Information:
Name(s) found:	SPRC_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|6981574\|ref\|NP_036788.1\| secreted protein, acidic, cysteine-rich (osteonectin) [Rattus norvegicus] [NCBI NR] gi\|38197690\|gb\|AAH61777.1\| Secreted protein, acidic, cysteine-rich (osteonectin) [Rattus norvegicus] [NCBI NR] gi\|2196884\|emb\|CAA74042.1\| osteonectin [Rattus norvegicus] [NCBI NR] gi\|149052664\|gb\|EDM04481.1\| secreted acidic cysteine rich glycoprotein, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149052661\|gb\|EDM04478.1\| secreted acidic cysteine rich glycoprotein, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149052658\|gb\|EDM04475.1\| secreted acidic cysteine rich glycoprotein, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149052657\|gb\|EDM04474.1\| secreted acidic cysteine rich glycoprotein, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|146345514\|sp\|P16975.4\|SPRC_RAT RecName: Full=SPARC; AltName: Full=Secreted protein acidic and rich in cysteine; AltName: Full=Osteonectin; Short=ON; AltName: Full=Basement-membrane protein 40; Short=BM-40; Flags: Precursor [NCBI NR] SPARC OS=Rattus norvegicus GN=Sparc PE=1 SV=4 [Swiss-Prot] secreted acidic cysteine rich glycoprotein; Secreted acidic cystein-rich glycoprotein (osteonectin) [HMR_022704-rand.fasta] secreted acidic cysteine rich glycoprotein [Rattus norvegicus]gi\|38197690\|gb\|AAH61777.1\| Secreted acidic cysteine rich glycoprotein [Rattus norvegicus]gi\|2196884\|emb\|CAA74042.1\| osteonectin [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Secreted acidic cysteine rich glycoprotein [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] (NM_012656) secreted acidic cystein-rich glycoprotein (osteonectin) [Rattus norvegicus] [NCBI-RefSeq_human-mouse-rat_na_10-18-2006_con_reversed.fasta] SPARC precursor (Secreted protein acidic and rich in cysteine) (Osteonectin) (ON) (Basement-membrane protein 40) (BM-40) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] secreted acidic cysteine rich glycoprotein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] secreted acidic cysteine rich glycoprotein, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Secreted acidic cysteine rich glycoprotein [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] osteonectin [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] secreted protein, acidic, cysteine-rich (osteonectin) [Rattus norvegicus] [NCBI-RefSeq_human-rat_na_04-07-2009_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Sparc SPARC [rat-ipi-250309-contam.fasta] SPARC OS=Rattus norvegicus GN=Sparc [011711_HMR.fasta]
Organism:	Rattus norvegicus
Length:	301 amino acids
Gene Ontology:
Cellular Component:	platelet alpha granule lumen [UNKNOWN] nucleus [IDA] basement membrane [IEA] extracellular space [IDA] membrane-bounded vesicle [IDA] cytoplasm [IDA] extracellular matrix [UNKNOWN] extracellular region [UNKNOWN][IEA] proteinaceous extracellular matrix [IEA] intracellular [IDA]
Biological Process:	response to L-ascorbic acid [IEP] response to cytokine stimulus [IEP] inner ear development [IEP] signal transduction [IEA] response to cAMP [IEP] response to cadmium ion [IEP] response to peptide hormone stimulus [IEP] regulation of cell proliferation [UNKNOWN] heart development [IEP] response to gravity [IEP] response to ethanol [IEP] wound healing [IEP] ossification [IEP] response to calcium ion [IEP] cellular response to growth factor stimulus [UNKNOWN] response to glucocorticoid stimulus [IEP] response to lipopolysaccharide [IEP] response to lead ion [IEP] lung development [IMP]
Molecular Function:	extracellular matrix binding [UNKNOWN] protein binding [UNKNOWN] calcium ion binding [IDA][IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRAWIFFLLC LAGRALAAPQ TEAAEEMVAE ETVVEETGLP VGANPVQVEM GEFEEGAEET  60
   61 VEEVVAENPC QNHHCKHGKV CELDESNTPM CVCQDPTSCP APIGEFEKVC SNDNKTFDSS 120
  121 CHFFATKCTL EGTKKGHKLH LDYIGPCKYI APCLDSELTE FPLRMRDWLK NVLVTLYERD 180
  181 EGNNLLTEKQ KLRVKKIHEN EKRLEAGDHP VELLARDFEK NYNMYIFPVH WQFGQLDQHP 240
  241 IDGYLSHTEL APLRAPLIPM EHCTTRFFET CDLDNDKYIA LEEWAGCFGI KEQDINKDLV 300
  301 I

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: SPRC_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: