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Protein Overview: Syt7-PB

General Information:
Name(s) found: Syt7-PB / FBpp0088202 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • The gene Syt7 is referred to in FlyBase by the symbol Dmel\Syt7 (CG2381, FBgn0039900). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:299303..327107. It has the cytological map location 102B3. It is reported to have molecular function</span>: calcium-dependent phospholipid binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: synaptic vesicle exocytosis. 9 alleles are reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 327 amino acids

    Gene Ontology:
    Cellular Component: synaptic vesicle [IEA][ISS]
    membrane [IEA]
    Biological Process: vesicle-mediated transport [NAS]
    synaptic vesicle exocytosis [ISS]
    transport [IEA]
    neurotransmitter secretion [NAS]
    Molecular Function: transporter activity [IEA]
    calcium-dependent phospholipid binding [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASIVLIACL AILGLIITIA LFLAGGYLWW RHKRSQLQFI EPNEDEESSS YSLRAAQDIV  60
   61 DSGNPPTKPQ VPVAHAITTP LQNNINRKLN GFLSLRTPLI GGSGASQTKP QIISSVGNPG 120
  121 DGTTKDSANK SISMTDMYLD STDPSENVGQ IHFSLEYDFQ NTTLILKVLQ GKELPAKDLS 180
  181 GTSDPYVRVT LLPDKKHRLE TKIKRRTLNP RWNETFYFEG FPIQKLQSRV LHLHVFDYDR 240
  241 FSRDDSIGEV FLPLCQVDFA GKQSFWKALK PPAKDKCGEL LSSLCYHPSN SILTLTLIKA 300
  301 RNLKAKDING KSDPYVKVWL QFGDKRF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..262] PSI-BLAST 19.69897 Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!); PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain; Phospholipase C isozyme D1 (PLC-D1)
    2 View Details [263..327] PSI-BLAST 50.045757 Synaptogamin I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphoric diester hydrolase activity
    		•  1.67362368676764 bayes_pls_golite062009
  • hydrolase activity
    		•  1.32787318513099 bayes_pls_golite062009
  • binding
    		•  1.05707455695416 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.965274488318818 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.443779188608755 bayes_pls_golite062009
  • phospholipase C activity
    		•  0.357805917517475 bayes_pls_golite062009
  • protein binding
    		•  0.290051687524339 bayes_pls_golite062009
  • phospholipase activity
    		•  0.199167464219565 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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