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Protein Overview: gi|45550395, gi|...

General Information:
Name(s) found: gi|45550395 [NCBI NR]
gi|45445621 [NCBI NR]
Description(s) found:
Found 8 descriptions.
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  • gi|45550395|ref|NP_610511.2| matrix metalloproteinase 2, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|45445621|gb|AAF58911.5| matrix metalloproteinase 2, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1136 amino acids

    Gene Ontology:
    Cellular Component: dendrite [IMP]
    extracellular matrix [IEA]
    plasma membrane [IDA]
    Biological Process: imaginal disc fusion, thorax closure [IMP]
    oogenesis [IMP]
    imaginal disc eversion [IMP]
    proteolysis [IEA]
    basement membrane disassembly [IMP]
    Molecular Function: zinc ion binding [IEA]
    metalloendopeptidase activity [IDA][ISS][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSKYVLATL LALFAQSMCI QELSLPPEGS HSTAATRSKK AKTAISEDIM YNYLMQFDYL  60
   61 PKSDLETGAL RTEDQLKEAI RSLQSFGNIT VTGEIDSATA RLIQKPRCGV GDRRSADSFS 120
  121 PDNLYHEIGS NVRVRRFALQ GPKWSRTDLT WSCGRTEFEP SNPRLLGLGF RGTEPIENPF 180
  181 ANRPLTQPQQ QQLAGANEQL QLTIFGCLCS SVASKPSKRD DAAIEATKAI AFCHFCDLTP 240
  241 KVAQQNFISS SQYIERNYRA HIYIAMRIYK CVALIDMKES RKKKMGNAKR KEQDHRVQPA 300
  301 EKDVRLLMSA RQSGAFLMGM YLLMGAHRVG KRQRSKKGAI FRCRGRALIF PFGSGKVRGE 360
  361 RGASQHAVVM AKATVFRCSS LAPFRLHLVF SPCHSTRCNF LAFIFVLSAV PDPRAHRISP 420
  421 AFRTHGCCYV TLAVTGAKIC YGHNSEQAKR NGGEDASGKI LKSSDFYACI YELRELGNDI 480
  481 NDIYVTELQH KRRRNGRALT ANRQKVNMQQ TIALYNLKCT SLLQQLHNCH MVNRSMPDAS 540
  541 KVERMVQTAL DVWANHSKLT FREVYSDQAD IQILFARRAH GDGYKFDGPG QVLAHAFYPG 600
  601 EGRGGDAHFD ADETWNFDGE SDDSHGTNFL NVALHELGHS LGLAHSAIPD AVMFPWYQNN 660
  661 EVAGNLPDDD RYGIQQLYGT KEKTWGPYKP QTTTTTTTTT TMRAMIYRAD KPAYWPWNNP 720
  721 SNNPNNDRNR ARERQEEERR RQEKERRRQE EERRHQEEER RRQVEERQRQ EEERWRQEQE 780
  781 RQEEENRRRK IEHKSQWERN PSKERNRPRE RQEMERRRQE QERQEQERQE QEDRRRERER 840
  841 DRQLEWERRN RNGAREPVTP TANTTPRPTN KPYPTVHRQH HHHNKPRKPK PDSCMTYYDA 900
  901 ISIIRGELFI FRGPYLWRIG TSGLYNGYPT EIRRHWSALP ENLTKVDAVY ENKQRQIVFF 960
  961 IGREYYVFNS VMLAPGFPKP LASLGLPPTL THIDASFVWG HNNRTYMTSG TLYWRIDDYT1020
 1021 GQVELDYPRD MSIWSGVGYN IDAAFQYLDG KTYFFKNLGY WEFNDDRMKV AHARAKLSAR1080
 1081 RWMQCARSAN EVDDEQRWTA SLVSEGEETG RSGSRELRIN HFILSILLLA IANWRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] FFAS03 3.63 Gelatinase A (MMP-2); Gelatinase A; Gelatinase A (MMP-2) type II modules
    2 View Details [415..1136] PSI-BLAST 134.0 Gelatinase A (MMP-2); Gelatinase A (MMP-2), C-terminal domain; Gelatinase A; Gelatinase A (MMP-2) type II modules

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • peptidase activity
    		•  0.23695590197447 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  0.0341081586881899 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle