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Protein Overview: gi|45445606, gi|...

General Information:
Name(s) found: gi|45552041 [NCBI NR]
gi|45445606 [NCBI NR]
Description(s) found:
Found 6 descriptions.
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  • gi|45552041|ref|NP_788300.2| KCNQ potassium channel, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|45445606|gb|AAF58829.4| KCNQ potassium channel, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 992 amino acids

    Gene Ontology:
    Cellular Component: voltage-gated potassium channel complex [IEA]
    integral to membrane [ISS]
    Biological Process: potassium ion transport [ISS]
    regulation of heart rate [IMP]
    transmembrane transport [IEA]
    embryonic development via the syncytial blastoderm [IMP]
    cardiac muscle contraction [IMP]
    Molecular Function: voltage-gated potassium channel activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPDNDIYAF YDIRGYKGKC RPGRPNSERI LQPRMSLLGK PLNYNRGTRR DVRYRRLQSR  60
   61 LYNFLERPRG LHAIFYHVMV FLMVFTCLAL SVFSTIKEYE EDAVYILFRM EILVVIWFTM 120
  121 EFGARLWSSG CRSRYQGCLG RLKFVKRPFC IIDIVTILAS IVVLGMGTSG QVFATSALRG 180
  181 LRFFQILRMV RMDRRGGTWK LLGSVVYAHR QELITTMYIG FLGLIFASFL VYMWEKDVND 240
  241 KFSNFAQALW WGITLCTVGY GDMVPITWQG KLIASCCALL GISFFALPAG ILGSGFALKV 300
  301 QQQQRQKHMI RRRQPAATLI QAVWRCYAAD EHSVSVATWN IHRVALPSPP ASRASSSFKH 360
  361 NTSFVARLPT IRRHKSQTIQ TPGGGDGGGV SKPPGSSRAS TRYTRTIRDI NASVENLEVV 420
  421 QNGKSMNPSF SEDSVAETTC LKNIKNSDAS QPATLANCKL SSSAGSLAQF PDRNRDRDQD 480
  481 RRGHGEGEGD QAEEQAKAGG SRRNLTIPVV LYGFLHGNFL GSTLSLRNPR VAPANDRDLE 540
  541 AGRDEDEVHK DTCQRSNTLP LPVKPDSPSG SPGSGRTGRF FAAASHFLET GFSSPNPIID 600
  601 VANEEDEPRC TQLTNRHKTA IRFIRKLKYF VARRKFKEAL KPYDVKDVME QYAAGHVDLL 660
  661 GRVKMLHLRL DQILGKQGSK AKDVYASKIS LASRVVKVER QVADIEEKLD ILIKAYMEDR 720
  721 DRFLALPLPA KPKIHSISPS HKPLHHAHNL AMIDVWKRTA ALSVHPEQVT TTPLLNPSAP 780
  781 DSSELRSLTA TQTPTTTTDA IATQTPMPPH VQHTATNTKS SVLNSYQLGS EKQQHNDVFM 840
  841 TELENRTKKR VTLSLHRSTS EPYSKQEQRI TIPDEGADSL DSSAKPTPPD SSIILIDEYE 900
  901 DFEEEDLNCE GEMDHFPTWE IDSDIGVEVD VDADADGDCD ESTEDTALLQ CATRTAIVIT 960
  961 PISPVSSAHN LQQLNDQTTT LNKSNLLPPD SG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..379] PSI-BLAST 74.69897 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [380..497] deduced N/A No confident structure predictions are available.
    3 View Details [498..688] deduced N/A No confident structure predictions are available.
    4 View Details [689..755] deduced N/A No confident structure predictions are available.
    5 View Details [756..992] MSA 5.259997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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