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Protein Overview: gi|45445605, gi|...

General Information:
Name(s) found: gi|45552039 [NCBI NR]
gi|45445605 [NCBI NR]
Description(s) found:
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  • gi|45552039|ref|NP_788299.2| KCNQ potassium channel, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|45445605|gb|AAF58830.3| KCNQ potassium channel, isoform B [Drosophila melanogaster] [NCBI NR]
  • (AAF58830) CG33135-PB [DrosMelano7227.FASTAC.txt]
  • CG33135-PB, isoform B [Drosophila melanogaster]gi|45552039|ref|NP_788299.2| CG33135-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • CG33135-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • KCNQ potassium channel CG33135-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
    • Organism: Drosophila melanogaster
    Length: 807 amino acids

    Gene Ontology:
    Cellular Component: voltage-gated potassium channel complex [IEA]
    integral to membrane [ISS]
    Biological Process: potassium ion transport [ISS]
    regulation of heart rate [IMP]
    transmembrane transport [IEA]
    embryonic development via the syncytial blastoderm [IMP]
    cardiac muscle contraction [IMP]
    Molecular Function: voltage-gated potassium channel activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDPDNDIYAF YDIRGYKGKC RPGRPNSERI LQPRMSLLGK PLNYNRGTRR DVRYRRLQSR  60
   61 LYNFLERPRG LHAIFYHVMV FLMVFTCLAL SVFSTIKEYE EDAVYILFRM EILVVIWFTM 120
  121 EFGARLWSSG CRSRYQGCLG RLKFVKRPFC IIDIVTILAS IVVLGMGTSG QVFATSALRG 180
  181 LRFFQILRMV RMDRRGGTWK LLGSVVYAHR QELITTMYIG FLGLIFASFL VYMWEKDVND 240
  241 KFSNFAQALW WGITLCTVGY GDMVPITWQG KLIASCCALL GISFFALPAG ILGSGFALKV 300
  301 QQQQRQKHMI RRRQPAATLI QAVWRCYAAD EHSVSVATWN IHRVALPSPP ASRASSSFKH 360
  361 NTSFVARLPT IRRHKSQTIQ TPGGGDGGGV SKPPGSSRAS TRYTRTIRDI NASVENLDEE 420
  421 DEPRCTQLTN RHKTAIRFIR KLKYFVARRK FKEALKPYDV KDVMEQYAAG HVDLLGRVKM 480
  481 LHLRLDQILG KQGSKAKDVY ASKISLASRV VKVERQVADI EEKLDILIKA YMEDRDRFLA 540
  541 LPLPAKPKIH SISPSHKPLH HAHNLAMIDV WKRTAALSVH PEQVTTTPLL NPSAPDSSEL 600
  601 RSLTATQTPT TTTDAIATQT PMPPHVQHTA TNTKSSVLNS YQLGSEKQQH NDVFMTELEN 660
  661 RTKKRVTLSL HRSTSEPYSK QEQRITIPDE GADSLDSSAK PTPPDSSIIL IDEYEDFEEE 720
  721 DLNCEGEMDH FPTWEIDSDI GVEVDVDADA DGDCDESTED TALLQCATRT AIVITPISPV 780
  781 SSAHNLQQLN DQTTTLNKSN LLPPDSG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..327] PSI-BLAST 69.39794 Mammalian Shaker Kv1.2 potassium channel- beta subunit complex
    2 View Details [328..496] PSI-BLAST 5.154902 No description for 2qksA was found.
    3 View Details [497..590] deduced N/A No confident structure predictions are available.
    4 View Details [591..807] MSA 4.277993 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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