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Protein Overview: CG8036-PC, CG8036-PB

General Information:
Name(s) found: CG8036-PC / FBpp0081371 [FlyBase]
CG8036-PB / FBpp0081370 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8036 (CG8036, FBgn0037607). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4493726..4499453. It has the cytological map location 85A5. Based on sequence similarity, it is predicted to have molecular function</span>: transketolase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 24 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8036 (CG8036, FBgn0037607). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4493726..4499453. It has the cytological map location 85A5. Based on sequence similarity, it is predicted to have molecular function</span>: transketolase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 24 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 626 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    Biological Process: metabolic process [IEA]
    Molecular Function: transketolase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYHKPEAKT VQDLKDLAQK LRIHSINATQ ASKSGHPTSC ASIAEIMSVL FFQQLRLNLK  60
   61 HPRDPSSDRF ILSKGHAAPI LYAAWAEAGL FPIADLNNLR KIDSDLEGHP TPRLNFIDVG 120
  121 TGSLGQGVAV GAGMAYVGKN FDKADYRTYV VVGDGESAEG SIWESLHFAG HYKLDNLCVI 180
  181 FDVNRLGQSE ATSLQHKLDV YRDRLEAFGF NAVVVDGHDV EELSKAFHCA AITKNKPTAI 240
  241 IAKTFKGRDF PNIEDLDNWH GKPLGDKAAE VVKHLEGLIV NKNVKLTPKP VPKTGAAPDV 300
  301 DINNIKLSSP PAYKLGDSIA TRLAYGTALA KIGQNNLRVV ALDGDTKNST FSDKLKNLDP 360
  361 QRYIECFIAE QNLVGVAVGA ACRRRTVAFV STFATFFTRA FDQIRMGAIS QTNVNFVGSH 420
  421 CGCSIGEDGP SQMGLEDIAM FRTIPGSTIF YPSDAVSTER AVELAANTKG VCFIRTSRPN 480
  481 TCVIYDNEEP FTIGRGKVVR QKSSDEVLLI GAGITLYECL AAADQLEKNC ITVRVIDPFT 540
  541 VKPLDAELII EHGKQCGGRV VVVEDHYQQG GLGEAVLSAL AGERNFVVKH LYVPTVPRSG 600
  601 PPSVLIDMFG ISARHVVNAV NEILKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..626] PSI-BLAST 162.0 Transketolase (TK), Pyr module; Transketolase (TK), PP module; Transketolase (TK), C-domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transketolase activity
    		•  6.17852985073866 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
    		•  2.93250853993668 bayes_pls_golite062009
  • pyruvate dehydrogenase activity
    		•  2.81702263447118 bayes_pls_golite062009
  • pyruvate dehydrogenase (acetyl-transferring) activity
    		•  2.6977837113283 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.21959520697519 bayes_pls_golite062009
  • binding
    		•  0.980920092099572 bayes_pls_golite062009
  • catalytic activity
    		•  0.545407789079971 bayes_pls_golite062009
  • thiamin pyrophosphate binding
    		•  0.297191393111081 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  0.173822256668691 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle